AF377

antibody from R&D Systems

Targeting: NRG1 GGF, HGL, HRG, NDF, NRG1-IT2

Western blot (Data presented on provider website)

Antibody Data

Product number

AF377

Provider

R&D Systems

Product name

Human NRG1-beta 1/HRG1-beta 1 Extracellular Domain Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects human NRG1-beta 1/HRG1-beta 1 in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with the EGF domain of recombinant human (rh) NRG1-beta 1/HRG1-beta 1 is observed and less than 1% cross-reactivity with rhNRG-2 is observed.

Reactivity

Human

Host

Goat

Conjugate

Unconjugated

Antigen sequence

AAA58639


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer.

Zhou BB, Peyton M, He B, Liu C, Girard L, Caudler E, Lo Y, Baribaud F, Mikami I, Reguart N, Yang G, Li Y, Yao W, Vaddi K, Gazdar AF, Friedman SM, Jablons DM, Newton RC, Fridman JS, Minna JD, Scherle PA
Cancer cell 2006 Jul;10(1):39-50