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- Antigen structure
- References [8]
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- Product number
- MAB377 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human Neuregulin-1/NRG1 Monoclonal Antibody (Clone 147724)
- Antibody type
- Monoclonal
- Antigen
- E. coli-derived recombinant human Neuregulin‑1/NRG1, Ser2-Lys246
- Description
- Protein A or G purified from hybridoma culture supernatant
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
AAA58639- Isotype
- IgG
- Vial size
- 500 µg
Submitted references Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model.
BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer and confers sensitivity to BET inhibitors.
Expression of the neuroprotective protein aryl hydrocarbon receptor nuclear translocator 2 correlates with neuronal stress and disability in models of multiple sclerosis.
Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury.
Fibroblast-derived neuregulin 1 promotes compensatory ErbB3 receptor signaling in mutant BRAF melanoma.
BRCA1-IRIS inactivation sensitizes ovarian tumors to cisplatin.
The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene.
Fractalkine/CX3CL1 enhances GABA synaptic activity at serotonin neurons in the rat dorsal raphe nucleus.
Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, Shinohara M, Liu CC, Du D, Sun H, Wen L, Xu H, Bu G, Chen XF
Nature communications 2019 Mar 25;10(1):1365
Nature communications 2019 Mar 25;10(1):1365
BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer and confers sensitivity to BET inhibitors.
Rhyasen GW, Yao Y, Zhang J, Dulak A, Castriotta L, Jacques K, Zhao W, Gharahdaghi F, Hattersley MM, Lyne PD, Clark E, Zinda M, Fawell SE, Mills GB, Chen H
PloS one 2018;13(7):e0200826
PloS one 2018;13(7):e0200826
Expression of the neuroprotective protein aryl hydrocarbon receptor nuclear translocator 2 correlates with neuronal stress and disability in models of multiple sclerosis.
Rahim T, Becquart P, Baeva ME, Quandt J
Journal of neuroinflammation 2018 Sep 19;15(1):270
Journal of neuroinflammation 2018 Sep 19;15(1):270
Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury.
Choi YK, Maki T, Mandeville ET, Koh SH, Hayakawa K, Arai K, Kim YM, Whalen MJ, Xing C, Wang X, Kim KW, Lo EH
Nature medicine 2016 Nov;22(11):1335-1341
Nature medicine 2016 Nov;22(11):1335-1341
Fibroblast-derived neuregulin 1 promotes compensatory ErbB3 receptor signaling in mutant BRAF melanoma.
Capparelli C, Rosenbaum S, Berger AC, Aplin AE
The Journal of biological chemistry 2015 Oct 2;290(40):24267-77
The Journal of biological chemistry 2015 Oct 2;290(40):24267-77
BRCA1-IRIS inactivation sensitizes ovarian tumors to cisplatin.
Paul BT, Blanchard Z, Ridgway M, ElShamy WM
Oncogene 2015 Jun 4;34(23):3036-52
Oncogene 2015 Jun 4;34(23):3036-52
The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene.
Chua YL, Ito Y, Pole JC, Newman S, Chin SF, Stein RC, Ellis IO, Caldas C, O'Hare MJ, Murrell A, Edwards PA
Oncogene 2009 Nov 19;28(46):4041-52
Oncogene 2009 Nov 19;28(46):4041-52
Fractalkine/CX3CL1 enhances GABA synaptic activity at serotonin neurons in the rat dorsal raphe nucleus.
Heinisch S, Kirby LG
Neuroscience 2009 Dec 15;164(3):1210-23
Neuroscience 2009 Dec 15;164(3):1210-23
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