Antibody data
- Antibody Data
- Antigen structure
- References [39]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 13626-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13626-1-AP, RRID:AB_2102017
- Product name
- FABP1 antibody
- Antibody type
- Polyclonal
- Description
- FABP1 antibody (Cat. #13626-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Targeting metabolic dysregulation in HCC: Development and validation of a dual-biomarker diagnostic model integrating ADH1C and BHMT.
Multi-omics reveals that 4'-O-β-D-glucosyl-5-O-methylvisamminol ameliorates acute liver injury by modulating the miR-30e-3p/Tfrc axis and a multi-dimensional network of ferroptosis, inflammation, metabolism, and gut microbiota.
Imperatorin ameliorates metabolic dysfunction-associated fatty liver disease through modulating Suv39h1/Fabps/Cept1 signalling pathway.
Gut microbiota dysbiosis contributes to diabetic nephropathy via affecting renal lipid deposition and inflammatory responses.
Hyodeoxycholic Acid Ameliorates Metabolic Syndrome Through Pathways of Primary Bile Acid Synthesis and Fatty Acid Degradation: Insights From a Rat Model.
Decoding HuH-7: a comprehensive genetic and molecular portrait of a widely used hepatocellular carcinoma model.
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Effects of inflammation on hypoxic renal tubular epithelial cell injury under high-glucose conditions and the regulatory role of miR-125b.
Overexpression of Apolipoprotein A-I Alleviates Insulin Resistance in MASLD Mice Through the PPARα Pathway.
Syncytin-1 deficiency impairs placental nutrient transport via PI3K/Akt/mTOR signaling.
Urinary fatty acid-binding protein 4 is a promising biomarker for glomerular damage in patients with diabetes mellitus.
Astragaloside IV attenuates renal tubule injury in DKD rats via suppression of CD36-mediated NLRP3 inflammasome activation.
Upregulation of Hepatic Glutathione S-Transferase Alpha 1 Ameliorates Metabolic Dysfunction-Associated Steatosis by Degrading Fatty Acid Binding Protein 1.
Sesamin alleviates lipid accumulation induced by oleic acid via PINK1/Parkin-mediated mitophagy in HepG2 cells.
Hepatocellular Carcinoma LINC01116 Outcompetes T Cells for Linoleic Acid and Accelerates Tumor Progression.
Hepatocyte-Specific PEX16 Abrogation in Mice Leads to Hepatocyte Proliferation, Alteration of Hepatic Lipid Metabolism, and Resistance to High-Fat Diet (HFD)-Induced Hepatic Steatosis and Obesity.
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling.
Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation.
Derlin-1 ameliorates nonalcoholic hepatic steatosis by promoting ubiquitylation and degradation of FABP1.
Structure-Activity Relationship Studies of Venglustat on NTMT1 Inhibition.
Millet Bran Protein Hydrolysate Displays the Anti-non-alcoholic Fatty Liver Disease Effect via Activating Peroxisome Proliferator-Activated Receptor γ to Restrain Fatty Acid Uptake.
α-Lactalbumin Peptide Asp-Gln-Trp Ameliorates Hepatic Steatosis and Oxidative Stress in Free Fatty Acids-Treated HepG2 Cells and High-Fat Diet-Induced NAFLD Mice by Activating the PPARα Pathway.
Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma.
Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells.
Adenosine-rich extract of Ganoderma lucidum: A safe and effective lipid-lowering substance.
Multi-Omics Analysis of Fatty Acid Metabolism in Thyroid Carcinoma.
Proteome analysis identified proteins associated with mitochondrial function and inflammation activation crucially regulating the pathogenesis of fatty liver disease.
PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1.
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
N(1)-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism.
PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Short hairpin RNA attenuates liver fibrosis by regulating the PPAR‑γ and NF‑κB pathways in HBV‑induced liver fibrosis in mice.
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
GLP-1 receptor agonist ameliorates obesity-induced chronic kidney injury via restoring renal metabolism homeostasis.
The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death.
A novel transgenic mouse model of lysosomal storage disorder.
Cao Z, Chen Z, Zhang Y, Tan Y, Shu Y, Bu K, Zeng H, Shu H, Huang J
Clinics and research in hepatology and gastroenterology 2026 May;50(5):102814
Clinics and research in hepatology and gastroenterology 2026 May;50(5):102814
Multi-omics reveals that 4'-O-β-D-glucosyl-5-O-methylvisamminol ameliorates acute liver injury by modulating the miR-30e-3p/Tfrc axis and a multi-dimensional network of ferroptosis, inflammation, metabolism, and gut microbiota.
Zhang T, Zou R, Chen Z, Li Y, Sun X, Sun X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158022
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158022
Imperatorin ameliorates metabolic dysfunction-associated fatty liver disease through modulating Suv39h1/Fabps/Cept1 signalling pathway.
Sun Y, Wang C, Wang Y, Hao R, Liu L, Jin Y, Sun H
British journal of pharmacology 2026 Mar;183(5):1104-1121
British journal of pharmacology 2026 Mar;183(5):1104-1121
Gut microbiota dysbiosis contributes to diabetic nephropathy via affecting renal lipid deposition and inflammatory responses.
Liu P, Hu P, Jin M, Wan Y, Wu J, Sun W, Tang Y, Huang L, Zhang D, Shi D, Xie T, Tong Y, Zheng H, Wang L, He H, Xu X
Journal of translational medicine 2026 Feb 23;24(1)
Journal of translational medicine 2026 Feb 23;24(1)
Hyodeoxycholic Acid Ameliorates Metabolic Syndrome Through Pathways of Primary Bile Acid Synthesis and Fatty Acid Degradation: Insights From a Rat Model.
Chen M, Huang K, Luo W, Zhang F, Gan H, Yang Z
Drug design, development and therapy 2025;19:3611-3630
Drug design, development and therapy 2025;19:3611-3630
Decoding HuH-7: a comprehensive genetic and molecular portrait of a widely used hepatocellular carcinoma model.
Luis DD, Liehr T, Kankel S, Weise A, Pentzold C, Buhl EM, Hardt KS, Keller DT, Schröder-Lange SK, Weiskirchen R
Frontiers in cell and developmental biology 2025;13:1648639
Frontiers in cell and developmental biology 2025;13:1648639
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Tao X, Gao Y, Jin Z, Lu S, Li Z, Guo S, Fan Q, Li J, Qiao C, Lei H, Zhang Z, Zhao C, Wu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Effects of inflammation on hypoxic renal tubular epithelial cell injury under high-glucose conditions and the regulatory role of miR-125b.
Shen X, Liu Y, Zhao J, Cheng Q, Yang G
Scientific reports 2025 Jul 1;15(1):21248
Scientific reports 2025 Jul 1;15(1):21248
Overexpression of Apolipoprotein A-I Alleviates Insulin Resistance in MASLD Mice Through the PPARα Pathway.
Wang Y, Zhang Y, Wang Y
International journal of molecular sciences 2025 Jan 26;26(3)
International journal of molecular sciences 2025 Jan 26;26(3)
Syncytin-1 deficiency impairs placental nutrient transport via PI3K/Akt/mTOR signaling.
Chen XL, Gong XX, Xiong ZL, Zhou D, Yang J, Zhang HF, Xue YS, Wang YN, Chen HB
The Journal of nutritional biochemistry 2025 Dec;146:110060
The Journal of nutritional biochemistry 2025 Dec;146:110060
Urinary fatty acid-binding protein 4 is a promising biomarker for glomerular damage in patients with diabetes mellitus.
Tanaka M, Sato T, Gohda T, Kamei N, Murakoshi M, Ishiwata E, Endo K, Kawaharata W, Aida H, Nakata K, Akiyama Y, Kubota M, Sanuki M, Suzuki T, Suzuki Y, Furuhashi M
Journal of diabetes investigation 2025 Apr;16(4):670-679
Journal of diabetes investigation 2025 Apr;16(4):670-679
Astragaloside IV attenuates renal tubule injury in DKD rats via suppression of CD36-mediated NLRP3 inflammasome activation.
Li X, Dong X, Zhang L, Zhang S, Huang W, Wang C, Huo Z, Li X, Zhang X, Jia X, Chen G, Kuang B
Frontiers in pharmacology 2024;15:1285797
Frontiers in pharmacology 2024;15:1285797
Upregulation of Hepatic Glutathione S-Transferase Alpha 1 Ameliorates Metabolic Dysfunction-Associated Steatosis by Degrading Fatty Acid Binding Protein 1.
Jiang J, Li H, Tang M, Lei L, Li HY, Dong B, Li JR, Wang XK, Sun H, Li JY, Xu JC, Gong Y, Jiang JD, Peng ZG
International journal of molecular sciences 2024 May 7;25(10)
International journal of molecular sciences 2024 May 7;25(10)
Sesamin alleviates lipid accumulation induced by oleic acid via PINK1/Parkin-mediated mitophagy in HepG2 cells.
Dong M, Zhang T, Liang X, Cheng X, Shi F, Yuan H, Zhang F, Jiang Q, Wang X
Biochemical and biophysical research communications 2024 May 14;708:149815
Biochemical and biophysical research communications 2024 May 14;708:149815
Hepatocellular Carcinoma LINC01116 Outcompetes T Cells for Linoleic Acid and Accelerates Tumor Progression.
Ma K, Chu J, Liu Y, Sun L, Zhou S, Li X, Ji C, Zhang N, Guo X, Liang S, Cui T, Hu Q, Wang J, Liu Y, Liu L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(21):e2400676
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(21):e2400676
Hepatocyte-Specific PEX16 Abrogation in Mice Leads to Hepatocyte Proliferation, Alteration of Hepatic Lipid Metabolism, and Resistance to High-Fat Diet (HFD)-Induced Hepatic Steatosis and Obesity.
Chen X, Wang L, Denning KL, Mazur A, Xu Y, Wang K, Lawrence LM, Wang X, Lu Y
Biomedicines 2024 Apr 30;12(5)
Biomedicines 2024 Apr 30;12(5)
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling.
Zhong J, He X, Gao X, Liu Q, Zhao Y, Hong Y, Zhu W, Yan J, Li Y, Li Y, Zheng N, Bao Y, Wang H, Ma J, Huang W, Liu Z, Lyu Y, Ke X, Jia W, Xie C, Hu Y, Sheng L, Li H
Nature communications 2023 Sep 6;14(1):5451
Nature communications 2023 Sep 6;14(1):5451
Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation.
Roberts MA, Deol KK, Mathiowetz AJ, Lange M, Leto DE, Stevenson J, Hashemi SH, Morgens DW, Easter E, Heydari K, Nalls MA, Bassik MC, Kampmann M, Kopito RR, Faghri F, Olzmann JA
Developmental cell 2023 Sep 25;58(18):1782-1800.e10
Developmental cell 2023 Sep 25;58(18):1782-1800.e10
Derlin-1 ameliorates nonalcoholic hepatic steatosis by promoting ubiquitylation and degradation of FABP1.
You H, Wen X, Wang X, Zhu C, Chen H, Bu L, Zhang J, Qu S
Free radical biology & medicine 2023 Oct;207:260-271
Free radical biology & medicine 2023 Oct;207:260-271
Structure-Activity Relationship Studies of Venglustat on NTMT1 Inhibition.
Deng Y, Dong G, Meng Y, Noinaj N, Huang R
Journal of medicinal chemistry 2023 Jan 26;66(2):1601-1615
Journal of medicinal chemistry 2023 Jan 26;66(2):1601-1615
Millet Bran Protein Hydrolysate Displays the Anti-non-alcoholic Fatty Liver Disease Effect via Activating Peroxisome Proliferator-Activated Receptor γ to Restrain Fatty Acid Uptake.
Shan S, Zhou J, Yin R, Zhang L, Shi J, Qiao Q, Li Z
Journal of agricultural and food chemistry 2023 Jan 25;71(3):1628-1642
Journal of agricultural and food chemistry 2023 Jan 25;71(3):1628-1642
α-Lactalbumin Peptide Asp-Gln-Trp Ameliorates Hepatic Steatosis and Oxidative Stress in Free Fatty Acids-Treated HepG2 Cells and High-Fat Diet-Induced NAFLD Mice by Activating the PPARα Pathway.
Chen H, Ma Y, Qi X, Tian J, Ma Y, Niu T
Molecular nutrition & food research 2023 Aug;67(16):e2200499
Molecular nutrition & food research 2023 Aug;67(16):e2200499
Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma.
Zhou X, Li Y, Yang C, Chen D, Wang T, Liu T, Yan W, Su Z, Peng B, Ren X
Life sciences 2023 Aug 15;327:121698
Life sciences 2023 Aug 15;327:121698
Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells.
Chen H, Qi X, Guan K, Wang R, Li Q, Ma Y
Journal of dairy science 2023 Apr;106(4):2271-2288
Journal of dairy science 2023 Apr;106(4):2271-2288
Adenosine-rich extract of Ganoderma lucidum: A safe and effective lipid-lowering substance.
Li H, Du Y, Ji H, Yang Y, Xu C, Li Q, Ran L, Wu C, Zhou Q, Wu S
iScience 2022 Nov 18;25(11):105214
iScience 2022 Nov 18;25(11):105214
Multi-Omics Analysis of Fatty Acid Metabolism in Thyroid Carcinoma.
Lu J, Zhang Y, Sun M, Ding C, Zhang L, Kong Y, Cai M, Miccoli P, Ma C, Yue X
Frontiers in oncology 2021;11:737127
Frontiers in oncology 2021;11:737127
Proteome analysis identified proteins associated with mitochondrial function and inflammation activation crucially regulating the pathogenesis of fatty liver disease.
Zhang L, Liu T, Hu C, Zhang X, Zhang Q, Shi K
BMC genomics 2021 Sep 4;22(1):640
BMC genomics 2021 Sep 4;22(1):640
PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1.
Xu Y, Denning KL, Lu Y
Biochemical pharmacology 2021 Oct;192:114678
Biochemical pharmacology 2021 Oct;192:114678
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
Song M, Zhang S, Tao Z, Li J, Shi Y, Xiong Y, Zhang W, Liu C, Chen S
Biomaterials 2021 Nov;278:121183
Biomaterials 2021 Nov;278:121183
N(1)-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism.
Wang Y, Wang J, Li X, Xiong X, Wang J, Zhou Z, Zhu X, Gu Y, Dominissini D, He L, Tian Y, Yi C, Fan Z
Nature communications 2021 Nov 2;12(1):6314
Nature communications 2021 Nov 2;12(1):6314
PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
Chen X, Xu Y, Denning KL, Grigore A, Lu Y
Free radical biology & medicine 2021 Jun;169:283-293
Free radical biology & medicine 2021 Jun;169:283-293
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Wang Y, Zhu Y, Niu J, Deng Q, Guo S, Jiang H, Peng Z, Xue Y, Peng H, Xuan L, Pan G
Toxicology and applied pharmacology 2020 Oct 1;404:115169
Toxicology and applied pharmacology 2020 Oct 1;404:115169
Short hairpin RNA attenuates liver fibrosis by regulating the PPAR‑γ and NF‑κB pathways in HBV‑induced liver fibrosis in mice.
Ye L, Chen T, Cao J, Sun L, Li W, Zhang C
International journal of oncology 2020 Nov;57(5):1116-1128
International journal of oncology 2020 Nov;57(5):1116-1128
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Zhang Z, Zong C, Jiang M, Hu H, Cheng X, Ni J, Yi X, Jiang B, Tian F, Chang MW, Su W, Zhu L, Li J, Xiang X, Miao C, Gorospe M, de Cabo R, Dou Y, Ju Z, Yang J, Jiang C, Yang Z, Wang W
Nature communications 2020 Jun 16;11(1):3067
Nature communications 2020 Jun 16;11(1):3067
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
Zong X, Cao X, Wang H, Xiao X, Wang Y, Lu Z
Frontiers in immunology 2019;10:1674
Frontiers in immunology 2019;10:1674
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Zhang Y, Li C, Hu C, Wu Q, Cai Y, Xing S, Lu H, Wang L, Huang D, Sun L, Li T, He X, Zhong X, Wang J, Gao P, Smith ZJ, Jia W, Zhang H
EMBO reports 2019 Oct 4;20(10):e48115
EMBO reports 2019 Oct 4;20(10):e48115
GLP-1 receptor agonist ameliorates obesity-induced chronic kidney injury via restoring renal metabolism homeostasis.
Wang C, Li L, Liu S, Liao G, Li L, Chen Y, Cheng J, Lu Y, Liu J
PloS one 2018;13(3):e0193473
PloS one 2018;13(3):e0193473
The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death.
Liu G, Wang K, Kuang S, Cao R, Bao L, Liu R, Liu H, Sun C
Cell death & disease 2018 Jun 7;9(6):689
Cell death & disease 2018 Jun 7;9(6):689
A novel transgenic mouse model of lysosomal storage disorder.
Ortiz-Miranda S, Ji R, Jurczyk A, Aryee KE, Mo S, Fletcher T, Shaffer SA, Greiner DL, Bortell R, Gregg RG, Cheng A, Hennings LJ, Rittenhouse AR
American journal of physiology. Gastrointestinal and liver physiology 2016 Nov 1;311(5):G903-G919
American journal of physiology. Gastrointestinal and liver physiology 2016 Nov 1;311(5):G903-G919
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The FABP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FABP1. This antibody recognizes human, mouse, rat antigen. The FABP1 antibody has been validated for the following applications: ELISA, WB analysis.