AP26391PU-N

antibody from Acris Antibodies GmbH

Targeting: FABP1 L-FABP

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AP26391PU-N

Provider

Acris Antibodies GmbH

Proper citation

Acris Antibodies GmbH Cat#AP26391PU-N, RRID:AB_11214977

Product name

anti FABP1

Antibody type

Polyclonal

Antigen

The L-FABP protein is derived from the human FABP1 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. L-FABP is localized in hepatocytes and brush cells found in the biliary tract, in mucosa of small and large intestine and in intestinal metaplasia of the gastric mucosa. Furthermore, L-FABP is present in the epithelium of the proximal tubule of the kidney.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

0.1 mg

Concentration

0.1 mg/ml