Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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Validation data
Reference
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- Product number
- 10351-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10351-1-AP, RRID:AB_2100056
- Product name
- Emerin antibody
- Antibody type
- Polyclonal
- Description
- Emerin antibody (Cat. #10351-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Defects in Emerin-Nucleoskeleton Binding Disrupt Nuclear Structure and Promote Breast Cancer Cell Motility and Metastasis.
CDK1 controls CHMP7-dependent nuclear envelope reformation.
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation.
Off-the-shelf proximity biotinylation for interaction proteomics.
Cytoplasmic control of intranuclear polarity by human cytomegalovirus.
EDMD-Causing Emerin Mutant Myogenic Progenitors Exhibit Impaired Differentiation Using Similar Mechanisms.
Emerin Is Required for Proper Nucleus Reassembly after Mitosis: Implications for New Pathogenetic Mechanisms for Laminopathies Detected in EDMD1 Patients.
Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane.
Nuclear envelope assembly defects link mitotic errors to chromothripsis.
Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression.
The effect of the lamin A and its mutants on nuclear structure, cell proliferation, protein stability, and mobility in embryonic cells.
DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes.
Emery-Dreifuss muscular dystrophy mutations impair TRC40-mediated targeting of emerin to the inner nuclear membrane.
Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence.
MacroH2A1 associates with nuclear lamina and maintains chromatin architecture in mouse liver cells.
Liddane AG, McNamara CA, Campbell MC, Mercier I, Holaska JM
Molecular cancer research : MCR 2021 Jul;19(7):1196-1207
Molecular cancer research : MCR 2021 Jul;19(7):1196-1207
CDK1 controls CHMP7-dependent nuclear envelope reformation.
Gatta AT, Olmos Y, Stoten CL, Chen Q, Rosenthal PB, Carlton JG
eLife 2021 Jul 21;10
eLife 2021 Jul 21;10
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation.
Merta H, Carrasquillo Rodríguez JW, Anjur-Dietrich MI, Vitale T, Granade ME, Harris TE, Needleman DJ, Bahmanyar S
Developmental cell 2021 Dec 20;56(24):3364-3379.e10
Developmental cell 2021 Dec 20;56(24):3364-3379.e10
Off-the-shelf proximity biotinylation for interaction proteomics.
Santos-Barriopedro I, van Mierlo G, Vermeulen M
Nature communications 2021 Aug 18;12(1):5015
Nature communications 2021 Aug 18;12(1):5015
Cytoplasmic control of intranuclear polarity by human cytomegalovirus.
Procter DJ, Furey C, Garza-Gongora AG, Kosak ST, Walsh D
Nature 2020 Nov;587(7832):109-114
Nature 2020 Nov;587(7832):109-114
EDMD-Causing Emerin Mutant Myogenic Progenitors Exhibit Impaired Differentiation Using Similar Mechanisms.
Iyer A, Holaska JM
Cells 2020 Jun 15;9(6)
Cells 2020 Jun 15;9(6)
Emerin Is Required for Proper Nucleus Reassembly after Mitosis: Implications for New Pathogenetic Mechanisms for Laminopathies Detected in EDMD1 Patients.
Dubińska-Magiera M, Kozioł K, Machowska M, Piekarowicz K, Filipczak D, Rzepecki R
Cells 2019 Mar 13;8(3)
Cells 2019 Mar 13;8(3)
Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane.
Blenski M, Kehlenbach RH
International journal of molecular sciences 2019 Jan 15;20(2)
International journal of molecular sciences 2019 Jan 15;20(2)
Nuclear envelope assembly defects link mitotic errors to chromothripsis.
Liu S, Kwon M, Mannino M, Yang N, Renda F, Khodjakov A, Pellman D
Nature 2018 Sep;561(7724):551-555
Nature 2018 Sep;561(7724):551-555
Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression.
Smith ER, Meng Y, Moore R, Tse JD, Xu AG, Xu XX
BMC cell biology 2017 Jan 14;18(1):8
BMC cell biology 2017 Jan 14;18(1):8
The effect of the lamin A and its mutants on nuclear structure, cell proliferation, protein stability, and mobility in embryonic cells.
Piekarowicz K, Machowska M, Dratkiewicz E, Lorek D, Madej-Pilarczyk A, Rzepecki R
Chromosoma 2017 Aug;126(4):501-517
Chromosoma 2017 Aug;126(4):501-517
DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes.
Samwer M, Schneider MWG, Hoefler R, Schmalhorst PS, Jude JG, Zuber J, Gerlich DW
Cell 2017 Aug 24;170(5):956-972.e23
Cell 2017 Aug 24;170(5):956-972.e23
Emery-Dreifuss muscular dystrophy mutations impair TRC40-mediated targeting of emerin to the inner nuclear membrane.
Pfaff J, Rivera Monroy J, Jamieson C, Rajanala K, Vilardi F, Schwappach B, Kehlenbach RH
Journal of cell science 2016 Feb 1;129(3):502-16
Journal of cell science 2016 Feb 1;129(3):502-16
Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence.
Lenain C, Gusyatiner O, Douma S, van den Broek B, Peeper DS
Carcinogenesis 2015 Nov;36(11):1263-74
Carcinogenesis 2015 Nov;36(11):1263-74
MacroH2A1 associates with nuclear lamina and maintains chromatin architecture in mouse liver cells.
Fu Y, Lv P, Yan G, Fan H, Cheng L, Zhang F, Dang Y, Wu H, Wen B
Scientific reports 2015 Nov 25;5:17186
Scientific reports 2015 Nov 25;5:17186
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10351-1-AP(EMD antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using EMD antibody 10351-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of EMD antibody (10351-1-AP for IP and Detection) with mouse skeletal muscle tissue lysate.
- Sample type
- tissue