Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [28]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 10351-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10351-1-AP, RRID:AB_2100056
- Product name
- Emerin antibody
- Antibody type
- Polyclonal
- Description
- Emerin antibody (Cat. #10351-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references OrthoID: profiling dynamic proteomes through time and space using mutually orthogonal chemical tools.
Emerin deficiency drives MCF7 cells to an invasive phenotype.
A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope.
Nuclear lamin A-associated proteins are required for centromere assembly.
Improved in situ characterization of protein complex dynamics at scale with thermal proximity co-aggregation.
Chromatin remodeling and nucleoskeleton synergistically control osteogenic differentiation in different matrix stiffnesses.
LAP1 supports nuclear adaptability during constrained melanoma cell migration and invasion.
Emerin interacts with histone methyltransferases to regulate repressive chromatin at the nuclear periphery.
The BAF A12T mutation disrupts lamin A/C interaction, impairing robust repair of nuclear envelope ruptures in Nestor-Guillermo progeria syndrome cells.
BCAP31 is involved in modulating colorectal cancer cell proliferation via the Emerin/β-catenin axis.
Recruitment of DNA to tumor-derived microvesicles.
Collective analysis of the expression and prognosis for LEM-domain proteins in prostate cancer.
Reticulon-like REEP4 at the inner nuclear membrane promotes nuclear pore complex formation.
Defects in Emerin-Nucleoskeleton Binding Disrupt Nuclear Structure and Promote Breast Cancer Cell Motility and Metastasis.
CDK1 controls CHMP7-dependent nuclear envelope reformation.
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation.
Off-the-shelf proximity biotinylation for interaction proteomics.
Cytoplasmic control of intranuclear polarity by human cytomegalovirus.
EDMD-Causing Emerin Mutant Myogenic Progenitors Exhibit Impaired Differentiation Using Similar Mechanisms.
Emerin Is Required for Proper Nucleus Reassembly after Mitosis: Implications for New Pathogenetic Mechanisms for Laminopathies Detected in EDMD1 Patients.
Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane.
Nuclear envelope assembly defects link mitotic errors to chromothripsis.
Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression.
The effect of the lamin A and its mutants on nuclear structure, cell proliferation, protein stability, and mobility in embryonic cells.
DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes.
Emery-Dreifuss muscular dystrophy mutations impair TRC40-mediated targeting of emerin to the inner nuclear membrane.
Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence.
MacroH2A1 associates with nuclear lamina and maintains chromatin architecture in mouse liver cells.
Lee A, Sung G, Shin S, Lee SY, Sim J, Nhung TTM, Nghi TD, Park SK, Sathieshkumar PP, Kang I, Mun JY, Kim JS, Rhee HW, Park KM, Kim K
Nature communications 2024 Feb 29;15(1):1851
Nature communications 2024 Feb 29;15(1):1851
Emerin deficiency drives MCF7 cells to an invasive phenotype.
Hansen E, Rolling C, Wang M, Holaska JM
bioRxiv : the preprint server for biology 2024 Aug 7;
bioRxiv : the preprint server for biology 2024 Aug 7;
A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope.
Lee S, Carrasquillo Rodrı Guez JW, Merta H, Bahmanyar S
The Journal of cell biology 2023 Sep 4;222(9)
The Journal of cell biology 2023 Sep 4;222(9)
Nuclear lamin A-associated proteins are required for centromere assembly.
Landeros A, Wallace DA, Rahi A, Magdongon CB, Suraneni P, Amin MA, Chakraborty M, Adam SA, Foltz DR, Varma D
bioRxiv : the preprint server for biology 2023 Sep 26;
bioRxiv : the preprint server for biology 2023 Sep 26;
Improved in situ characterization of protein complex dynamics at scale with thermal proximity co-aggregation.
Sun S, Zheng Z, Wang J, Li F, He A, Lai K, Zhang S, Lu JH, Tian R, Tan CSH
Nature communications 2023 Nov 24;14(1):7697
Nature communications 2023 Nov 24;14(1):7697
Chromatin remodeling and nucleoskeleton synergistically control osteogenic differentiation in different matrix stiffnesses.
Xu X, Zhang H, Li Y, Liu F, Jing Z, Ren M, Chen T, Fu Y, Wu Y, Ji P, Yang S
Materials today. Bio 2023 Jun;20:100661
Materials today. Bio 2023 Jun;20:100661
LAP1 supports nuclear adaptability during constrained melanoma cell migration and invasion.
Jung-Garcia Y, Maiques O, Monger J, Rodriguez-Hernandez I, Fanshawe B, Domart MC, Renshaw MJ, Marti RM, Matias-Guiu X, Collinson LM, Sanz-Moreno V, Carlton JG
Nature cell biology 2023 Jan;25(1):108-119
Nature cell biology 2023 Jan;25(1):108-119
Emerin interacts with histone methyltransferases to regulate repressive chromatin at the nuclear periphery.
Marano N, Holaska JM
Frontiers in cell and developmental biology 2022;10:1007120
Frontiers in cell and developmental biology 2022;10:1007120
The BAF A12T mutation disrupts lamin A/C interaction, impairing robust repair of nuclear envelope ruptures in Nestor-Guillermo progeria syndrome cells.
Janssen A, Marcelot A, Breusegem S, Legrand P, Zinn-Justin S, Larrieu D
Nucleic acids research 2022 Sep 9;50(16):9260-9278
Nucleic acids research 2022 Sep 9;50(16):9260-9278
BCAP31 is involved in modulating colorectal cancer cell proliferation via the Emerin/β-catenin axis.
Han L, Shi J, Zhao L, Deng J, Li Y, Zhao H, Wang H, Yan Y, Zou F
Experimental cell research 2022 Sep 1;418(1):113265
Experimental cell research 2022 Sep 1;418(1):113265
Recruitment of DNA to tumor-derived microvesicles.
Clancy JW, Sheehan CS, Boomgarden AC, D'Souza-Schorey C
Cell reports 2022 Mar 1;38(9):110443
Cell reports 2022 Mar 1;38(9):110443
Collective analysis of the expression and prognosis for LEM-domain proteins in prostate cancer.
He T, Zhang Y, Li X, Liu C, Zhu G, Yin X, Zhang Z, Zhao K, Wang Z, Zhao P, Wang K
World journal of surgical oncology 2022 Jun 2;20(1):174
World journal of surgical oncology 2022 Jun 2;20(1):174
Reticulon-like REEP4 at the inner nuclear membrane promotes nuclear pore complex formation.
Golchoubian B, Brunner A, Bragulat-Teixidor H, Neuner A, Akarlar BA, Ozlu N, Schlaitz AL
The Journal of cell biology 2022 Feb 7;221(2)
The Journal of cell biology 2022 Feb 7;221(2)
Defects in Emerin-Nucleoskeleton Binding Disrupt Nuclear Structure and Promote Breast Cancer Cell Motility and Metastasis.
Liddane AG, McNamara CA, Campbell MC, Mercier I, Holaska JM
Molecular cancer research : MCR 2021 Jul;19(7):1196-1207
Molecular cancer research : MCR 2021 Jul;19(7):1196-1207
CDK1 controls CHMP7-dependent nuclear envelope reformation.
Gatta AT, Olmos Y, Stoten CL, Chen Q, Rosenthal PB, Carlton JG
eLife 2021 Jul 21;10
eLife 2021 Jul 21;10
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation.
Merta H, Carrasquillo Rodríguez JW, Anjur-Dietrich MI, Vitale T, Granade ME, Harris TE, Needleman DJ, Bahmanyar S
Developmental cell 2021 Dec 20;56(24):3364-3379.e10
Developmental cell 2021 Dec 20;56(24):3364-3379.e10
Off-the-shelf proximity biotinylation for interaction proteomics.
Santos-Barriopedro I, van Mierlo G, Vermeulen M
Nature communications 2021 Aug 18;12(1):5015
Nature communications 2021 Aug 18;12(1):5015
Cytoplasmic control of intranuclear polarity by human cytomegalovirus.
Procter DJ, Furey C, Garza-Gongora AG, Kosak ST, Walsh D
Nature 2020 Nov;587(7832):109-114
Nature 2020 Nov;587(7832):109-114
EDMD-Causing Emerin Mutant Myogenic Progenitors Exhibit Impaired Differentiation Using Similar Mechanisms.
Iyer A, Holaska JM
Cells 2020 Jun 15;9(6)
Cells 2020 Jun 15;9(6)
Emerin Is Required for Proper Nucleus Reassembly after Mitosis: Implications for New Pathogenetic Mechanisms for Laminopathies Detected in EDMD1 Patients.
Dubińska-Magiera M, Kozioł K, Machowska M, Piekarowicz K, Filipczak D, Rzepecki R
Cells 2019 Mar 13;8(3)
Cells 2019 Mar 13;8(3)
Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane.
Blenski M, Kehlenbach RH
International journal of molecular sciences 2019 Jan 15;20(2)
International journal of molecular sciences 2019 Jan 15;20(2)
Nuclear envelope assembly defects link mitotic errors to chromothripsis.
Liu S, Kwon M, Mannino M, Yang N, Renda F, Khodjakov A, Pellman D
Nature 2018 Sep;561(7724):551-555
Nature 2018 Sep;561(7724):551-555
Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression.
Smith ER, Meng Y, Moore R, Tse JD, Xu AG, Xu XX
BMC cell biology 2017 Jan 14;18(1):8
BMC cell biology 2017 Jan 14;18(1):8
The effect of the lamin A and its mutants on nuclear structure, cell proliferation, protein stability, and mobility in embryonic cells.
Piekarowicz K, Machowska M, Dratkiewicz E, Lorek D, Madej-Pilarczyk A, Rzepecki R
Chromosoma 2017 Aug;126(4):501-517
Chromosoma 2017 Aug;126(4):501-517
DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes.
Samwer M, Schneider MWG, Hoefler R, Schmalhorst PS, Jude JG, Zuber J, Gerlich DW
Cell 2017 Aug 24;170(5):956-972.e23
Cell 2017 Aug 24;170(5):956-972.e23
Emery-Dreifuss muscular dystrophy mutations impair TRC40-mediated targeting of emerin to the inner nuclear membrane.
Pfaff J, Rivera Monroy J, Jamieson C, Rajanala K, Vilardi F, Schwappach B, Kehlenbach RH
Journal of cell science 2016 Feb 1;129(3):502-16
Journal of cell science 2016 Feb 1;129(3):502-16
Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence.
Lenain C, Gusyatiner O, Douma S, van den Broek B, Peeper DS
Carcinogenesis 2015 Nov;36(11):1263-74
Carcinogenesis 2015 Nov;36(11):1263-74
MacroH2A1 associates with nuclear lamina and maintains chromatin architecture in mouse liver cells.
Fu Y, Lv P, Yan G, Fan H, Cheng L, Zhang F, Dang Y, Wu H, Wen B
Scientific reports 2015 Nov 25;5:17186
Scientific reports 2015 Nov 25;5:17186
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10351-1-AP(EMD antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using EMD antibody 10351-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of EMD antibody (10351-1-AP for IP and Detection) with mouse skeletal muscle tissue lysate.
- Sample type
- tissue
