Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- AF2335 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal Aminopeptidase N/CD13 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse Aminopeptidase N/CD13 in direct ELISAs and Western blots.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Precapillary sphincters maintain perfusion in the cerebral cortex.
GPR124 facilitates pericyte polarization and migration by regulating the formation of filopodia during ischemic injury.
Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL.
Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell.
Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury.
Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2.
Required growth facilitators propel axon regeneration across complete spinal cord injury.
Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function.
Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
Thalidomide Reduces Hemorrhage of Brain Arteriovenous Malformations in a Mouse Model.
Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling.
Prostacyclin prevents pericyte loss and demyelination induced by lysophosphatidylcholine in the central nervous system.
Adiponectin expression protects against angiotensin II-mediated inflammation and accelerated atherosclerosis.
Pericyte loss influences Alzheimer-like neurodegeneration in mice.
Grubb S, Cai C, Hald BO, Khennouf L, Murmu RP, Jensen AGK, Fordsmann J, Zambach S, Lauritzen M
Nature communications 2020 Jan 20;11(1):395
Nature communications 2020 Jan 20;11(1):395
GPR124 facilitates pericyte polarization and migration by regulating the formation of filopodia during ischemic injury.
Chen DY, Sun NH, Lu YP, Hong LJ, Cui TT, Wang CK, Chen XH, Wang SS, Feng LL, Shi WX, Fukunaga K, Chen Z, Lu YM, Han F
Theranostics 2019;9(20):5937-5955
Theranostics 2019;9(20):5937-5955
Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL.
Rajani RM, Ratelade J, Domenga-Denier V, Hase Y, Kalimo H, Kalaria RN, Joutel A
Acta neuropathologica communications 2019 Nov 21;7(1):187
Acta neuropathologica communications 2019 Nov 21;7(1):187
Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell.
Ayyaz A, Kumar S, Sangiorgi B, Ghoshal B, Gosio J, Ouladan S, Fink M, Barutcu S, Trcka D, Shen J, Chan K, Wrana JL, Gregorieff A
Nature 2019 May;569(7754):121-125
Nature 2019 May;569(7754):121-125
Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury.
Bellver-Landete V, Bretheau F, Mailhot B, Vallières N, Lessard M, Janelle ME, Vernoux N, Tremblay MÈ, Fuehrmann T, Shoichet MS, Lacroix S
Nature communications 2019 Jan 31;10(1):518
Nature communications 2019 Jan 31;10(1):518
Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2.
Hendrikx S, Coso S, Prat-Luri B, Wetterwald L, Sabine A, Franco CA, Nassiri S, Zangger N, Gerhardt H, Delorenzi M, Petrova TV
Cell reports 2019 Jan 29;26(5):1227-1241.e6
Cell reports 2019 Jan 29;26(5):1227-1241.e6
Required growth facilitators propel axon regeneration across complete spinal cord injury.
Anderson MA, O'Shea TM, Burda JE, Ao Y, Barlatey SL, Bernstein AM, Kim JH, James ND, Rogers A, Kato B, Wollenberg AL, Kawaguchi R, Coppola G, Wang C, Deming TJ, He Z, Courtine G, Sofroniew MV
Nature 2018 Sep;561(7723):396-400
Nature 2018 Sep;561(7723):396-400
Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function.
Koizumi K, Hattori Y, Ahn SJ, Buendia I, Ciacciarelli A, Uekawa K, Wang G, Hiller A, Zhao L, Voss HU, Paul SM, Schaffer C, Park L, Iadecola C
Nature communications 2018 Sep 19;9(1):3816
Nature communications 2018 Sep 19;9(1):3816
Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
Ma Q, Zhao Z, Sagare AP, Wu Y, Wang M, Owens NC, Verghese PB, Herz J, Holtzman DM, Zlokovic BV
Molecular neurodegeneration 2018 Oct 19;13(1):57
Molecular neurodegeneration 2018 Oct 19;13(1):57
Thalidomide Reduces Hemorrhage of Brain Arteriovenous Malformations in a Mouse Model.
Zhu W, Chen W, Zou D, Wang L, Bao C, Zhan L, Saw D, Wang S, Winkler E, Li Z, Zhang M, Shen F, Shaligram S, Lawton M, Su H
Stroke 2018 May;49(5):1232-1240
Stroke 2018 May;49(5):1232-1240
Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling.
Nikolakopoulou AM, Zhao Z, Montagne A, Zlokovic BV
PloS one 2017;12(4):e0176225
PloS one 2017;12(4):e0176225
Prostacyclin prevents pericyte loss and demyelination induced by lysophosphatidylcholine in the central nervous system.
Muramatsu R, Kuroda M, Matoba K, Lin H, Takahashi C, Koyama Y, Yamashita T
The Journal of biological chemistry 2015 May 1;290(18):11515-25
The Journal of biological chemistry 2015 May 1;290(18):11515-25
Adiponectin expression protects against angiotensin II-mediated inflammation and accelerated atherosclerosis.
van Stijn CM, Kim J, Barish GD, Tietge UJ, Tangirala RK
PloS one 2014;9(1):e86404
PloS one 2014;9(1):e86404
Pericyte loss influences Alzheimer-like neurodegeneration in mice.
Sagare AP, Bell RD, Zhao Z, Ma Q, Winkler EA, Ramanathan A, Zlokovic BV
Nature communications 2013;4:2932
Nature communications 2013;4:2932
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Aminopeptidase N/CD13 in Mouse Kidney. Aminopeptidase N/CD13 in Mouse Kidney.