Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- ELISA [1]
- Flow cytometry [3]
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Validation data
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- Product number
- Ab176429 - Provider product page
- Provider
- Aladdin Scientific
- Product name
- Inotuzumab (anti-CD22)
- Antibody type
- Recombinant
- Description
- Inotuzumab (anti-CD22) is a humanized IgG4, _ antibody that targets human CD22. Inotuzumab (anti-CD22) can be linked to a toxic agent ozogamicin as an antibody-drug conjugate (ADC). Inotuzumab (anti-CD22) can be used for the research of acute lymphoblastic leukemia and non-Hodgkin lymphoma.Purity>95% (SDS-PAGE&SEC)Endotoxin Level< 1.0EU/mg
- Reactivity
- Human
- Conjugate
- Unconjugated
- Vial size
- 100_g,10mg,1mg,5mg
- Concentration
- Lot by Lot
- Storage
- Store at -80_ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
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Supportive validation
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Inotuzumab (anti-CD22) (Ab176429) - ELISA Immobilized Recombinant Human Siglec-2/CD22 Protein (rp169575) at 1.0 μg/mL can bind Inotuzumab (anti-CD22) (Ab176429) with the EC₅₀ of 20.07 ng/mL.
Supportive validation
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Inotuzumab (anti-CD22) (Ab176429) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD22 with Inotuzumab (anti-CD22) (Ab176429) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156250).
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Inotuzumab (anti-CD22) (Ab176429) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD22 (red) with Inotuzumab (anti-CD22) (Ab176429) conjugated with biotin and detected with SA-PE (rp156250). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Inotuzumab (anti-CD22) (Ab176429) - Flow Cytometry Flow Cytometry analysis of Ramos cells labelling CD22 (red) with Inotuzumab (anti-CD22) (Ab176429). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.