AFC-TAB-179

antibody from Creative Biolabs

Targeting: TNFRSF9 4-1BB, CD137, ILA

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Flow cytometry (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

AFC-TAB-179

Provider

Creative Biolabs

Product name

Afuco? Anti-TNFRSF9 ADCC Recombinant Antibody (Urelumab), ADCC Enhanced

Antibody type

Monoclonal

Description

This product is an ADCC enhanced antibody produced by our Afuco? platform. Recombinant monoclonal antibody to 4-1BB. Urelumab (ue rel' ue mab; also known as BMS-663513 and anti-4-1BB antibody) is a fully human IgG4 monoclonal antibody for the treatment of cancer and solid tumors. Urelumab targets the CD137 receptor. It specifically binds to and activates CD137-expressing immune cells, stimulating an immune response, in particular a cytotoxic T cell response, against tumor cells.

Reactivity

Human

Host

Human

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

Urelumab

Storage

Store at +4¡ãC short term (1-2 weeks). Aliquot and store at -20¡ãC long term. Avoid repeated freeze/thaw cycles.