Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 311502 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#311502, RRID:AB_314881
- Product name
- Purified anti-human 4-1BB Ligand (CD137L)
- Antibody type
- Monoclonal
- Antigen
- CD137L (4-1BB Ligand)
- Description
- 4-1BB ligand, also known as CDw137L, is a 97 kD member of the TNF superfamily mainly expressed on APCs, activated B and T cells. It has been reported to be important in T cell proliferation and cytokine production through interaction with 4-1BB receptor. 4-1BB ligand appears to be able to act as a costimulatory molecule without the engagement of other costimulatory molecules such as CD28.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references Induction of proliferation and monocytic differentiation of human CD34+ cells by CD137 ligand signaling.
Jiang D, Yue PS, Drenkard D, Schwarz H
Stem cells (Dayton, Ohio) 2008 Sep;26(9):2372-81
Stem cells (Dayton, Ohio) 2008 Sep;26(9):2372-81
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- HuT 78 (T lymphoma cell line)stained with purified 5F4, thendetected with biotinylated antimouseIgG followed by Sav-PE
- Conjugate
- Unconjugated