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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN350344 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350344, RRID:AB_10781362
- Product name
- anti-Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the VHS domain of human GGA3 conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat, mouse, chicken.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100 μL
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references The consensus coding sequences of human breast and colorectal cancers.
GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination.
Autoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif.
GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors.
Sorting of mannose 6-phosphate receptors mediated by the GGAs.
Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE
Science (New York, N.Y.) 2006 Oct 13;314(5797):268-74
Science (New York, N.Y.) 2006 Oct 13;314(5797):268-74
GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination.
Shiba Y, Katoh Y, Shiba T, Yoshino K, Takatsu H, Kobayashi H, Shin HW, Wakatsuki S, Nakayama K
The Journal of biological chemistry 2004 Feb 20;279(8):7105-11
The Journal of biological chemistry 2004 Feb 20;279(8):7105-11
Autoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif.
Doray B, Bruns K, Ghosh P, Kornfeld SA
Proceedings of the National Academy of Sciences of the United States of America 2002 Jun 11;99(12):8072-7
Proceedings of the National Academy of Sciences of the United States of America 2002 Jun 11;99(12):8072-7
GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors.
Takatsu H, Yoshino K, Toda K, Nakayama K
The Biochemical journal 2002 Jul 15;365(Pt 2):369-78
The Biochemical journal 2002 Jul 15;365(Pt 2):369-78
Sorting of mannose 6-phosphate receptors mediated by the GGAs.
Puertollano R, Aguilar RC, Gorshkova I, Crouch RJ, Bonifacino JS
Science (New York, N.Y.) 2001 Jun 1;292(5522):1712-6
Science (New York, N.Y.) 2001 Jun 1;292(5522):1712-6
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