Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11989-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11989-1-AP, RRID:AB_2290597
- Product name
- CD147 antibody
- Antibody type
- Polyclonal
- Description
- CD147 antibody (Cat. #11989-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CD147 deficiency in T cells prevents thymic involution by inhibiting the EMT process in TECs in the presence of TGFβ.
Resveratrol-induced apoptosis is associated with regulating the miR-492/CD147 pathway in malignant melanoma cells.
LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma.
α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling.
Effects of excess thromboxane A2 on placental development and nutrient transporters in a Mus musculus model of fetal growth restriction.
Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication.
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Triptolide inhibits the migration and invasion of human prostate cancer cells via Caveolin-1/CD147/MMPs pathway.
The fucosylated CD147 enhances the autophagy in epithelial ovarian cancer cells.
Inhibition of STAT3 reduces proliferation and invasion in salivary gland adenoid cystic carcinoma.
C4.4A as a biomarker of head and neck squamous cell carcinoma and correlated with epithelial mesenchymal transition.
Association Study between an SNP in CD147 and Its Expression With Acute Coronary Syndrome in a Jiangsu Chinese Population.
A chimeric antibody targeting CD147 inhibits hepatocellular carcinoma cell motility via FAK-PI3K-Akt-Girdin signaling pathway.
Clinical significance of Keap1 and Nrf2 in oral squamous cell carcinoma.
Association of increased ligand cyclophilin A and receptor CD147 with hypoxia, angiogenesis, metastasis and prognosis of tongue squamous cell carcinoma.
Chen R, Wang K, Feng Z, Zhang MY, Wu J, Geng JJ, Chen ZN
Cellular & molecular immunology 2021 Jan;18(1):171-181
Cellular & molecular immunology 2021 Jan;18(1):171-181
Resveratrol-induced apoptosis is associated with regulating the miR-492/CD147 pathway in malignant melanoma cells.
Zhao S, Tang L, Chen W, Su J, Li F, Chen X, Wu L
Naunyn-Schmiedeberg's archives of pharmacology 2021 Apr;394(4):797-807
Naunyn-Schmiedeberg's archives of pharmacology 2021 Apr;394(4):797-807
LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma.
Zhang W, Han L, Xing P, Liu B, Sun Z, Zhou W, Dong J
Naunyn-Schmiedeberg's archives of pharmacology 2020 Dec;393(12):2543-2551
Naunyn-Schmiedeberg's archives of pharmacology 2020 Dec;393(12):2543-2551
α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling.
Wang L, Li S, Yu X, Han Y, Wu Y, Wang S, Chen X, Zhang J, Wang S
Journal of physiology and biochemistry 2019 Jun;75(2):199-207
Journal of physiology and biochemistry 2019 Jun;75(2):199-207
Effects of excess thromboxane A2 on placental development and nutrient transporters in a Mus musculus model of fetal growth restriction.
Gibbins KJ, Gibson-Corley KN, Brown AS, Wieben M, Law RC, Fung CM
Biology of reproduction 2018 May 1;98(5):695-704
Biology of reproduction 2018 May 1;98(5):695-704
Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication.
Wang T, Wang B, Huang H, Zhang C, Zhu Y, Pei B, Cheng C, Sun L, Wang J, Jin Q, Zhao Z
PLoS pathogens 2017 Oct;13(10):e1006674
PLoS pathogens 2017 Oct;13(10):e1006674
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Zhai Y, Wu B, Li J, Yao XY, Zhu P, Chen ZN
Journal of molecular medicine (Berlin, Germany) 2016 Jan;94(1):71-82
Journal of molecular medicine (Berlin, Germany) 2016 Jan;94(1):71-82
Triptolide inhibits the migration and invasion of human prostate cancer cells via Caveolin-1/CD147/MMPs pathway.
Yuan S, Wang L, Chen X, Fan B, Yuan Q, Zhang H, Yang D, Wang S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1776-1782
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1776-1782
The fucosylated CD147 enhances the autophagy in epithelial ovarian cancer cells.
Hu Z, Cai M, Deng L, Zhu L, Gao J, Tan M, Liu J, Lin B
Oncotarget 2016 Dec 13;7(50):82921-82932
Oncotarget 2016 Dec 13;7(50):82921-82932
Inhibition of STAT3 reduces proliferation and invasion in salivary gland adenoid cystic carcinoma.
Bu LL, Deng WW, Huang CF, Liu B, Zhang WF, Sun ZJ
American journal of cancer research 2015;5(5):1751-61
American journal of cancer research 2015;5(5):1751-61
C4.4A as a biomarker of head and neck squamous cell carcinoma and correlated with epithelial mesenchymal transition.
Liu JF, Mao L, Bu LL, Ma SR, Huang CF, Zhang WF, Sun ZJ
American journal of cancer research 2015;5(12):3505-15
American journal of cancer research 2015;5(12):3505-15
Association Study between an SNP in CD147 and Its Expression With Acute Coronary Syndrome in a Jiangsu Chinese Population.
Yan J, Mao Y, Wang C, Wang Z
Medicine 2015 Oct;94(42):e1537
Medicine 2015 Oct;94(42):e1537
A chimeric antibody targeting CD147 inhibits hepatocellular carcinoma cell motility via FAK-PI3K-Akt-Girdin signaling pathway.
Wang Y, Yuan L, Yang XM, Wei D, Wang B, Sun XX, Feng F, Nan G, Wang Y, Chen ZN, Bian H
Clinical & experimental metastasis 2015 Jan;32(1):39-53
Clinical & experimental metastasis 2015 Jan;32(1):39-53
Clinical significance of Keap1 and Nrf2 in oral squamous cell carcinoma.
Huang CF, Zhang L, Ma SR, Zhao ZL, Wang WM, He KF, Zhao YF, Zhang WF, Liu B, Sun ZJ
PloS one 2013;8(12):e83479
PloS one 2013;8(12):e83479
Association of increased ligand cyclophilin A and receptor CD147 with hypoxia, angiogenesis, metastasis and prognosis of tongue squamous cell carcinoma.
Huang C, Sun Z, Sun Y, Chen X, Zhu X, Fan C, Liu B, Zhao Y, Zhang W
Histopathology 2012 Apr;60(5):793-803
Histopathology 2012 Apr;60(5):793-803
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 11989-1-AP(CD147 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CD147 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CD147. This antibody recognizes human antigen. The CD147 antibody has been validated for the following applications: ELISA, WB, IHC analysis.