Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 10917-2-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10917-2-AP, RRID:AB_2108279
- Product name
- GATA1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GATA1 antibody (Cat. #10917-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Biomimetic Nanotechnology Overcoming the Blood-Testis Barrier for Testicular Protection in Chemotherapy.
Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis-Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish.
BMSC-derived exosomal ANTXR1 inhibits erythroid differentiation by suppressing the TLR4/MyD88/NF-κB signaling pathway.
Regulating mitochondrial oxidative phosphorylation and MAPK signaling: wedelolactone as a novel therapeutic for radiation-induced thrombocytopenia.
Ribosomal protein deficiencies linked to Diamond-Blackfan anemia induce distinctive alterations of ATF4 expression.
Differential effect of cancer-associated fibroblast-derived extracellular vesicles on cisplatin resistance in oral squamous cell carcinoma via miR-876-3p.
Superenhancer-driven circRNA Myst4 involves in pulmonary artery smooth muscle cell ferroptosis in pulmonary hypertension.
Harmine promotes megakaryocyte differentiation and thrombopoiesis by activating the Rac1/Cdc42/JNK pathway through a potential target of 5-HTR2A.
Alnustone promotes megakaryocyte differentiation and platelet production via the interleukin-17A/interleukin-17A receptor/Src/RAC1/MEK/ERK signaling pathway.
BF170 hydrochloride enhances the emergence of hematopoietic stem and progenitor cells.
Xanthotoxin, a novel inducer of platelet formation, promotes thrombocytopoiesis via IL-1R1 and MEK/ERK signaling.
FLI1 Induces Megakaryopoiesis Gene Expression Through WAS/WIP-Dependent and Independent Mechanisms; Implications for Wiskott-Aldrich Syndrome.
Proof of Gene Doping in a Mouse Model with a Human Erythropoietin Gene Transferred Using an Adenoviral Vector.
GATA1 promotes colorectal cancer cell proliferation, migration and invasion via activating AKT signaling pathway.
microRNA-23a, -27a and -24 synergistically regulate JAK1/Stat3 cascade and serve as novel therapeutic targets in human acute erythroid leukemia.
The transcription factor GATA1 and the histone methyltransferase SET7 interact to promote VEGF-mediated angiogenesis and tumor growth and predict clinical outcome of breast cancer.
An C, Sun J, Ma A, Mei Q, Liu B, Lu L, Yang Y, Yu W, Song T, Gao Q, Shi L, Yue Q, Wei H, Zhao X
Biomaterials research 2026;30:0314
Biomaterials research 2026;30:0314
Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis-Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish.
Shi J, Lai F, Shen Z, Zhang X, Wang H, Liu W, Wang Y, Li K, Li G, Fang Y, Liu JX
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(12):e13762
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(12):e13762
BMSC-derived exosomal ANTXR1 inhibits erythroid differentiation by suppressing the TLR4/MyD88/NF-κB signaling pathway.
Chen D, Lin L, Wu Y, Huang K, Zhang H, Chen Q
Scientific reports 2026 Apr 16;
Scientific reports 2026 Apr 16;
Regulating mitochondrial oxidative phosphorylation and MAPK signaling: wedelolactone as a novel therapeutic for radiation-induced thrombocytopenia.
Li Z, Li Q, Wu S, Mei X, Qi X, Liu S, Qiao G, Shen H, Luo J, Zeng J, Huang F, Li R, Wang L
Frontiers in pharmacology 2025;16:1508215
Frontiers in pharmacology 2025;16:1508215
Ribosomal protein deficiencies linked to Diamond-Blackfan anemia induce distinctive alterations of ATF4 expression.
Lorenzo-Martín LF, Robles-Valero J, Ramírez-Cota R, Gaspar SG, Fuentes P, Gentilella A, Bustelo XR, Dosil M
iScience 2025 Apr 18;28(4):112138
iScience 2025 Apr 18;28(4):112138
Differential effect of cancer-associated fibroblast-derived extracellular vesicles on cisplatin resistance in oral squamous cell carcinoma via miR-876-3p.
Kang SH, Oh SY, Lee KY, Lee HJ, Kim MS, Kwon TG, Kim JW, Lee ST, Choi SY, Hong SH
Theranostics 2024;14(2):460-479
Theranostics 2024;14(2):460-479
Superenhancer-driven circRNA Myst4 involves in pulmonary artery smooth muscle cell ferroptosis in pulmonary hypertension.
He S, Bai J, Zhang L, Yuan H, Ma C, Wang X, Guan X, Mei J, Zhu X, Xin W, Zhu D
iScience 2024 Oct 18;27(10):110900
iScience 2024 Oct 18;27(10):110900
Harmine promotes megakaryocyte differentiation and thrombopoiesis by activating the Rac1/Cdc42/JNK pathway through a potential target of 5-HTR2A.
Liu X, Lai J, Zhang X, Wu A, Zhou L, Li Y, Huang Q, Huang X, Li H, Lan C, Liu J, Huang F, Wu J
Phytotherapy research : PTR 2024 Nov;38(11):5134-5149
Phytotherapy research : PTR 2024 Nov;38(11):5134-5149
Alnustone promotes megakaryocyte differentiation and platelet production via the interleukin-17A/interleukin-17A receptor/Src/RAC1/MEK/ERK signaling pathway.
Li Y, Lai J, Ran M, Yi T, Zhou L, Luo J, Liu X, Tang X, Huang M, Xie X, Li H, Yang Y, Zou W, Wu J
European journal of pharmacology 2024 May 15;971:176548
European journal of pharmacology 2024 May 15;971:176548
BF170 hydrochloride enhances the emergence of hematopoietic stem and progenitor cells.
Liu W, Ding Y, Shen Z, Xu C, Yi W, Wang D, Zhou Y, Zon LI, Liu JX
Development (Cambridge, England) 2024 Jul 1;151(13)
Development (Cambridge, England) 2024 Jul 1;151(13)
Xanthotoxin, a novel inducer of platelet formation, promotes thrombocytopoiesis via IL-1R1 and MEK/ERK signaling.
Lai J, Li Y, Ran M, Huang Q, Huang F, Zhu L, Wu Y, Zou W, Xie X, Tang Y, Yang F, Wu A, Ge G, Wu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114811
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114811
FLI1 Induces Megakaryopoiesis Gene Expression Through WAS/WIP-Dependent and Independent Mechanisms; Implications for Wiskott-Aldrich Syndrome.
Wang C, Sample KM, Gajendran B, Kapranov P, Liu W, Hu A, Zacksenhaus E, Li Y, Hao X, Ben-David Y
Frontiers in immunology 2021;12:607836
Frontiers in immunology 2021;12:607836
Proof of Gene Doping in a Mouse Model with a Human Erythropoietin Gene Transferred Using an Adenoviral Vector.
Sugasawa T, Nakano T, Fujita SI, Matsumoto Y, Ishihara G, Aoki K, Yanazawa K, Ono S, Tamai S, Manevich L, Ueda H, Ishibashi N, Tamai K, Kanki Y, Yoshida Y, Watanabe K, Takemasa T, Kawakami Y, Takekoshi K
Genes 2021 Aug 16;12(8)
Genes 2021 Aug 16;12(8)
GATA1 promotes colorectal cancer cell proliferation, migration and invasion via activating AKT signaling pathway.
Yu J, Liu M, Liu H, Zhou L
Molecular and cellular biochemistry 2019 Jul;457(1-2):191-199
Molecular and cellular biochemistry 2019 Jul;457(1-2):191-199
microRNA-23a, -27a and -24 synergistically regulate JAK1/Stat3 cascade and serve as novel therapeutic targets in human acute erythroid leukemia.
Su R, Dong L, Zou D, Zhao H, Ren Y, Li F, Yi P, Li L, Zhu Y, Ma Y, Wang J, Wang F, Yu J
Oncogene 2016 Nov 17;35(46):6001-6014
Oncogene 2016 Nov 17;35(46):6001-6014
The transcription factor GATA1 and the histone methyltransferase SET7 interact to promote VEGF-mediated angiogenesis and tumor growth and predict clinical outcome of breast cancer.
Zhang Y, Liu J, Lin J, Zhou L, Song Y, Wei B, Luo X, Chen Z, Chen Y, Xiong J, Xu X, Ding L, Ye Q
Oncotarget 2016 Mar 1;7(9):9859-75
Oncotarget 2016 Mar 1;7(9):9859-75
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 10917-2-AP(GATA1 antibody) at dilution of 1:1200
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The GATA1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GATA1. This antibody recognizes human,mouse,rat antigen. The GATA1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.