BS6852

antibody from Bioworld Technology, Inc

Targeting: SELPLG CD162, PSGL-1

Immunocytochemistry

Immunohistochemistry

Antibody data

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Validation data

Product number: BS6852 - Provider product page
Provider: Bioworld Technology, Inc
Product name: SELPLG polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human SELPLG.
Description: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
Reactivity: Human
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SELPLG protein structure - BS6852 shown in red.