Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN262947 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Selectin P Ligand (SELPLG) antibody
- Antibody type
- Monoclonal
- Description
- IgM purified
- Reactivity
- Human, Mouse
- Host
- Rat
- Isotype
- IgM
- Antibody clone number
- HECA-452
- Vial size
- 0.1 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Do not freeze.
Submitted references Therapeutic effects of combination using glucosamine plus tacrolimus (FK-506) on the development of atopic dermatitis-like skin lesions in NC/Nga mice.
Vitamins A and D are potent inhibitors of cutaneous lymphocyte-associated antigen expression.
The monoclonal antibody CHO-131 binds to a core 2 O-glycan terminated with sialyl-Lewis x, which is a functional glycan ligand for P-selectin.
The binding of T cell-expressed P-selectin glycoprotein ligand-1 to E- and P-selectin is differentially regulated.
ELAM-1 is an adhesion molecule for skin-homing T cells.
The cutaneous lymphocyte antigen is a skin lymphocyte homing receptor for the vascular lectin endothelial cell-leukocyte adhesion molecule 1.
A unique phenotype of skin-associated lymphocytes in humans. Preferential expression of the HECA-452 epitope by benign and malignant T cells at cutaneous sites.
High endothelial differentiation in human lymphoid and inflammatory tissues defined by monoclonal antibody HECA-452.
Kim CH, Cheong KA, Park CD, Lee AY
Scandinavian journal of immunology 2012 May;75(5):471-8
Scandinavian journal of immunology 2012 May;75(5):471-8
Vitamins A and D are potent inhibitors of cutaneous lymphocyte-associated antigen expression.
Yamanaka K, Dimitroff CJ, Fuhlbrigge RC, Kakeda M, Kurokawa I, Mizutani H, Kupper TS
The Journal of allergy and clinical immunology 2008 Jan;121(1):148-157.e3
The Journal of allergy and clinical immunology 2008 Jan;121(1):148-157.e3
The monoclonal antibody CHO-131 binds to a core 2 O-glycan terminated with sialyl-Lewis x, which is a functional glycan ligand for P-selectin.
Walcheck B, Leppanen A, Cummings RD, Knibbs RN, Stoolman LM, Alexander SR, Mattila PE, McEver RP
Blood 2002 Jun 1;99(11):4063-9
Blood 2002 Jun 1;99(11):4063-9
The binding of T cell-expressed P-selectin glycoprotein ligand-1 to E- and P-selectin is differentially regulated.
Borges E, Pendl G, Eytner R, Steegmaier M, Zöllner O, Vestweber D
The Journal of biological chemistry 1997 Nov 7;272(45):28786-92
The Journal of biological chemistry 1997 Nov 7;272(45):28786-92
ELAM-1 is an adhesion molecule for skin-homing T cells.
Picker LJ, Kishimoto TK, Smith CW, Warnock RA, Butcher EC
Nature 1991 Feb 28;349(6312):796-9
Nature 1991 Feb 28;349(6312):796-9
The cutaneous lymphocyte antigen is a skin lymphocyte homing receptor for the vascular lectin endothelial cell-leukocyte adhesion molecule 1.
Berg EL, Yoshino T, Rott LS, Robinson MK, Warnock RA, Kishimoto TK, Picker LJ, Butcher EC
The Journal of experimental medicine 1991 Dec 1;174(6):1461-6
The Journal of experimental medicine 1991 Dec 1;174(6):1461-6
A unique phenotype of skin-associated lymphocytes in humans. Preferential expression of the HECA-452 epitope by benign and malignant T cells at cutaneous sites.
Picker LJ, Michie SA, Rott LS, Butcher EC
The American journal of pathology 1990 May;136(5):1053-68
The American journal of pathology 1990 May;136(5):1053-68
High endothelial differentiation in human lymphoid and inflammatory tissues defined by monoclonal antibody HECA-452.
Duijvestijn AM, Horst E, Pals ST, Rouse BN, Steere AC, Picker LJ, Meijer CJ, Butcher EC
The American journal of pathology 1988 Jan;130(1):147-55
The American journal of pathology 1988 Jan;130(1):147-55
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
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- Experimental details
- IHC
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS