orb44713

antibody from Biorbyt

Targeting: CD163 M130, MM130, SCARI1

Western blot (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

orb44713

Provider

Biorbyt

Proper citation

Biorbyt Cat#orb44713, RRID:AB_10990688

Product name

Anti-Hu CD163 Purified

Antibody type

Monoclonal

Description

Mouse monoclonal to CD163. CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold.

Reactivity

Human

Conjugate

Unconjugated

Antibody clone number

GHI/61

Vial size

0.1 mg

Concentration

1 mg/ml

Storage

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.