333607

antibody from BioLegend
Targeting: CD163 M130, MM130, SCARI1
Provider product page for 333607

Antibody data

Product number
333607 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#333607, RRID:AB_1134006
Product name
PerCP/Cy5.5 anti-human CD163
Antibody type
Monoclonal
Antigen
CD163
Description
CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, Hemoglobin-Haptoglobin Complex Receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kuffer cells, monocytes, subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP) resulting in soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammation diseases.
Reactivity
Human, Simian
Host
Mouse
Conjugate
Far-Red dye
Isotype
IgG
Vial size
25 Tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
CD163 protein structure - 333607 shown in red.