333610

antibody from BioLegend

Targeting: CD163 M130, MM130, SCARI1

Antibody data

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Validation data

Product number: 333610 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#333610, RRID:AB_2074533
Product name: APC anti-human CD163
Antibody type: Monoclonal
Antigen: CD163
Description: CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, Hemoglobin-Haptoglobin Complex Receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kuffer cells, monocytes, subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP) resulting in soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammation diseases.
Reactivity: Human, Simian
Host: Mouse
Conjugate: Red dye
Isotype: IgG
Vial size: 100 tests
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

CD163 protein structure - 333610 shown in red.