Explore
Validate
Learn
Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- NB110-59935 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-59935, RRID:AB_892323
- Product name
- Mouse Monoclonal CD163 Antibody
- Antibody type
- Monoclonal
- Description
- Tissue culture supernatant. This CD163 molecule is a type I membrane protein also known as M130 antigen, Ber-Mac3, Ki-M8 or SM4. CD163 protein is restricted in its expression to the monocytic/macrophage lineage. It is reported to be present on all circulating monocytes and most tissue macrophages except those found in the mantle zone and germinal centers of lymphoid follicles, interdigitating reticulum cells, and Langerhans cells. Multinucleated cells within inflammatory lesions are reported not to express CD163 protein. The protein is upregulated by glucocorticoids and is downregulated by immunosuppressant cyclosporin A and phorbol esters.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.5 ml
- Storage
- Store at 4C. Do not freeze.
Submitted references An image dataset related to automated macrophage detection in immunostained lymphoma tissue samples.
Lack of CD8+ T-cell co-localization with Kaposi's sarcoma-associated herpesvirus infected cells in Kaposi's sarcoma tumors.
The Presence of Cyclooxygenase 2, Tumor-Associated Macrophages, and Collagen Alignment as Prognostic Markers for Invasive Breast Carcinoma Patients.
Signal Transducer and Activator of Transcription 3 for the Differentiation of Hepatocellular Carcinoma from Cirrhosis.
The clinical importance of tumour-infiltrating macrophages and dendritic cells in periampullary adenocarcinoma differs by morphological subtype.
Increased FcγRIIB dominance contributes to the emergence of resistance to therapeutic antibodies in chronic lymphocytic leukaemia patients.
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients.
Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and fibrosis in chronic hepatitis C.
Unicommissural aortic valves: gross, histological, and immunohistochemical analysis of 52 cases (1978-2008).
Macrophage secretory products induce an inflammatory phenotype in hepatocytes.
Wagner M, Reinke S, Hänsel R, Klapper W, Braumann UD
GigaScience 2020 Mar 1;9(3)
GigaScience 2020 Mar 1;9(3)
Lack of CD8+ T-cell co-localization with Kaposi's sarcoma-associated herpesvirus infected cells in Kaposi's sarcoma tumors.
Lidenge SJ, Tso FY, Ngalamika O, Kolape J, Ngowi JR, Mwaiselage J, Wood C, West JT
Oncotarget 2020 Apr 28;11(17):1556-1572
Oncotarget 2020 Apr 28;11(17):1556-1572
The Presence of Cyclooxygenase 2, Tumor-Associated Macrophages, and Collagen Alignment as Prognostic Markers for Invasive Breast Carcinoma Patients.
Esbona K, Yi Y, Saha S, Yu M, Van Doorn RR, Conklin MW, Graham DS, Wisinski KB, Ponik SM, Eliceiri KW, Wilke LG, Keely PJ
The American journal of pathology 2018 Mar;188(3):559-573
The American journal of pathology 2018 Mar;188(3):559-573
Signal Transducer and Activator of Transcription 3 for the Differentiation of Hepatocellular Carcinoma from Cirrhosis.
Li YP, Wang WZ, Chen XQ, Li LB, Liang ZY, Ru K, Li JN
Chinese medical journal 2017 Nov 20;130(22):2686-2690
Chinese medical journal 2017 Nov 20;130(22):2686-2690
The clinical importance of tumour-infiltrating macrophages and dendritic cells in periampullary adenocarcinoma differs by morphological subtype.
Lundgren S, Karnevi E, Elebro J, Nodin B, Karlsson MCI, Eberhard J, Leandersson K, Jirström K
Journal of translational medicine 2017 Jul 3;15(1):152
Journal of translational medicine 2017 Jul 3;15(1):152
Increased FcγRIIB dominance contributes to the emergence of resistance to therapeutic antibodies in chronic lymphocytic leukaemia patients.
Burgess M, Mapp S, Mazzieri R, Cheung C, Chambers L, Mattarollo SR, Mollee P, Gill D, Saunders NA
Oncogene 2017 Apr 27;36(17):2366-2376
Oncogene 2017 Apr 27;36(17):2366-2376
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients.
Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, Sosman JA, McDermott DF, Powderly JD, Gettinger SN, Kohrt HE, Horn L, Lawrence DP, Rost S, Leabman M, Xiao Y, Mokatrin A, Koeppen H, Hegde PS, Mellman I, Chen DS, Hodi FS
Nature 2014 Nov 27;515(7528):563-7
Nature 2014 Nov 27;515(7528):563-7
Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and fibrosis in chronic hepatitis C.
Gadd VL, Melino M, Roy S, Horsfall L, O'Rourke P, Williams MR, Irvine KM, Sweet MJ, Jonsson JR, Clouston AD, Powell EE
Liver international : official journal of the International Association for the Study of the Liver 2013 Apr;33(4):569-79
Liver international : official journal of the International Association for the Study of the Liver 2013 Apr;33(4):569-79
Unicommissural aortic valves: gross, histological, and immunohistochemical analysis of 52 cases (1978-2008).
Fealey ME, Edwards WD, Miller DV, Maleszewski JJ
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2012 Jul-Aug;21(4):324-33
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2012 Jul-Aug;21(4):324-33
Macrophage secretory products induce an inflammatory phenotype in hepatocytes.
Melino M, Gadd VL, Walker GV, Skoien R, Barrie HD, Jothimani D, Horsfall L, Jones A, Sweet MJ, Thomas GP, Clouston AD, Jonsson JR, Powell EE
World journal of gastroenterology 2012 Apr 21;18(15):1732-44
World journal of gastroenterology 2012 Apr 21;18(15):1732-44
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CD163 Antibody (10D6) [NB110-59935] - Human tonsil.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CD163 Antibody (10D6) [NB110-59935] - Human lymph node stained with CD163 antibody showing cytoplasmic staining in non-germinal center cells. Image from verified customer review.
