CABT-BL8274

antibody from Creative Diagnostics

Targeting: SLAMF1 CD150, SLAM

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-BL8274

Provider

Creative Diagnostics

Product name

Anti-SLAMF1 Monoclonal antibody, clone 0E2 [FITC]

Antibody type

Monoclonal

Description

CD150, designated SLAM (Signaling Lymphocyte Activation Molecule) or CDw150, belongs to the immunoglobulin gene superfamily and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells.

Reactivity

Mouse

Host

Rat

Conjugate

Green dye

Isotype

IgG

Antibody clone number

0.00E+00

Vial size

25 ug