Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL8275 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-SLAMF1 Monoclonal antibody, clone 0E2 [PE]
- Antibody type
- Monoclonal
- Description
- CD150, designated SLAM (Signaling Lymphocyte Activation Molecule) or CDw150, belongs to the immunoglobulin gene superfamily and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Yellow dye
- Isotype
- IgG
- Antibody clone number
- 0.00E+00
- Vial size
- 25 ug
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