Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
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- Product number
- NBP2-32942-0.1mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal CD6 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CD6 Antibody (3F7B5) [NBP2-32942] - Formalin-fixed, paraffin-embedded human tonsil (10X) stained with CD6 MAb (3F7B5).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CD6 Antibody (3F7B5) [NBP2-32942] - Formalin-fixed, paraffin-embedded human tonsil (20X) stained with CD6 MAb (3F7B5).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: CD6 Antibody (3F7B5) [NBP2-32942] - Flow Cytometric Analysis of MOLT-4 cells. CD6 Antibody (3F7B5) followed by goat anti-Mouse IgG-CF488 (Blue); Isotype control (Red).