ABIN94206

antibody from antibodies-online

Targeting: CD6 Tp120

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN94206

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN94206, RRID:AB_10784238

Product name

anti-CD6 (CD6) antibody

Antibody type

Monoclonal

Antigen

Human CD6 antigen purified by immunoaffinity chromatography from HBP-ALL cellsfollowed by preparative SDS-PAGE of non-boiled non-reduced sample (excised piece of gelcorresponding to the 100 kDa zone).

Description

Purified from ascites by protein-A affinity chromatography.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

MEM-98

Vial size

0.1 mg

Concentration

1 mg/ml

Storage

4°C

References

Submitted references

Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse.

Castro MA, Oliveira MI, Nunes RJ, Fabre S, Barbosa R, Peixoto A, Brown MH, Parnes JR, Bismuth G, Moreira A, Rocha B, Carmo AM
Journal of immunology (Baltimore, Md. : 1950) 2007 Apr 1;178(7):4351-61

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CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76.

Hassan NJ, Simmonds SJ, Clarkson NG, Hanrahan S, Puklavec MJ, Bomb M, Barclay AN, Brown MH
Molecular and cellular biology 2006 Sep;26(17):6727-38