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- Product number
- Ab176610 - Provider product page
- Provider
- Aladdin Scientific
- Product name
- Itolizumab (anti-CD6)
- Antibody type
- Recombinant
- Description
- Itolizumab (anti-CD6) is a humanized recombinant anti-CD6 monoclonal antibody (MAb) targeting the extracellular SRCR distal domain 1 of CD6. Itolizumab (anti-CD6) reduces T-cell proliferation and inhibits the production of pro-inflammatory cytokines, such as INF-_, TNF_ and IL-6. Itolizumab (anti-CD6) can be used in the research of psoriasis, rheumatoid arthritis (RA), COVID-19.Purity>95% (SDS-PAGE&SEC)Endotoxin Level< 1.0EU/mg
- Reactivity
- Human, Mouse, Rat
- Conjugate
- Unconjugated
- Vial size
- 100_g,10mg,1mg,5mg
- Concentration
- Lot by Lot
- Storage
- Store at -80_ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
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Supportive validation
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Itolizumab (anti-CD6) (Ab176610) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD6 with Itolizumab (anti-CD6) (Ab176610) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156250).
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Itolizumab (anti-CD6) (Ab176610) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD6 (red) with Itolizumab (anti-CD6) (Ab176610) conjugated with biotin and detected with SA-PE (rp156250). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Itolizumab (anti-CD6) (Ab176610) - Flow Cytometry Flow Cytometry analysis of MOLT-4 cells labelling CD6 (red) with Itolizumab (anti-CD6) (Ab176610). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Itolizumab (anti-CD6) (Ab176610) - Flow Cytometry Flow Cytometry analysis of Jurkat cells labelling CD6 (red) with Itolizumab (anti-CD6) (Ab176610). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
