Ab183440

antibody from Aladdin Scientific

Targeting: CD40 Bp50, p50, TNFRSF5

ELISA (Supportive data in Antibodypedia)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

Ab183440

Provider

Aladdin Scientific

Product name

Teneliximab (anti-CD40)

Antibody type

Recombinant

Description

Teneliximab (anti-CD40) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (anti-CD40) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell depletion.Purity>95% (SDS-PAGE&SEC)Endotoxin Level< 1.0EU/mg

Reactivity

Human

Conjugate

Unconjugated

Vial size

100_g,10mg,1mg,5mg

Concentration

Lot by Lot

Storage

Store at -80_ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.

ELISA

Supportive validation

Submitted by

Aladdin Scientific (provider)

Main image

Experimental details

Teneliximab (anti-CD40) (Ab183440) - ELISA Immobilized Recombinant Human CD40 Protein (rp144000) at 1.0 μg/mL can bind Teneliximab (anti-CD40) (Ab183440) with the EC50 of 11.50 ng/mL.​

Flow cytometry

Supportive validation

Submitted by

Aladdin Scientific (provider)

Main image

Experimental details

Teneliximab (anti-CD40) (Ab183440) - Flow Cytometry Flow Cytometry analysis of Raji cells labelling CD40 (red) with Teneliximab (anti-CD40) (Ab183440). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Supportive validation

Submitted by

Aladdin Scientific (provider)

Main image

Experimental details

Teneliximab (anti-CD40) (Ab183440) - Flow Cytometry Flow Cytometry analysis of U-2OS cells labelling CD40 (red) with Teneliximab (anti-CD40) (Ab183440). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.