orb137661

antibody from Biorbyt
Targeting: ICAM3 CD50, CDW50, ICAM-R
Provider product page for orb137661
Western blot
ELISA
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry
Flow cytometry

Antibody data

Product number
orb137661 - Provider product page
Provider
Biorbyt
Product name
Mouse anti ICAM-3
Antibody type
Monoclonal
Description
Mouse monoclonal to ICAM-3. Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a type I transmembrane glycoprotein, which normally contain 2-9 immunoglobulin-like C2-type domains, and binds to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM-3 has previously been implicated in apoptotic cell clearance, although its precise role in the clearance process is ill defined.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Antibody clone number
BH10
Vial size
0.1 mg
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
ICAM3 protein structure - orb137661 shown in red.