Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 310939 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#310939, RRID:AB_2562827
- Product name
- Purified anti-human CD69 (MaxPar® Ready)
- Antibody type
- Monoclonal
- Antigen
- 0
- Description
- CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.
- Reactivity
- Human, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- FN50
- Vial size
- 100 µg
- Concentration
- 1 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human PBMCs were incubated for 6 hours in media alone (bottom) or with PMA and Ionomycin (top) in the presence of monensin and brefeldin A. Cells were then fixed, permeabilized, and stained with 154Sm-anti-CD45 (HI30) and 162Dy-anti-CD69 (FN50).
- Conjugate
- Unconjugated