AGTO-G083P

antibody from Creative Biolabs

Targeting: CD72 CD72b, LYB2

No application information provided.

Antibody Data

Product number

AGTO-G083P

Provider

Creative Biolabs

Product name

Anti-CD72 immunotoxin J3-109 (IgG)-PAP

Antibody type

Monoclonal

Description

This immunotoxin was achieved by conjugating/fusing the Anti-CD72 monoclonal antibody to Pokeweed antiviral protein. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells and the toxin enters cells by receptor-mediated endocytosis. Then PAP is introduced into the cytoplasm where it eventually causes cell death by inactivating ribosomes. It was designed for treatment of acute lymphoblastic leukemias (ALL).

Reactivity

Human

Host

Mouse