BS7682

antibody from Bioworld Technology, Inc
Targeting: CD82 IA4, KAI1, R2, ST6, TSPAN27
Provider product page for BS7682
Western blot
Immunohistochemistry

Antibody data

Product number
BS7682 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CD82 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CD82.
Description
The transmembrane 4 superfamily (TM4SF) is a family of leukocyte surface glycoproteins that presumably cross the cell membrane four times. These proteins may be involved in transmembrane signal transduction regulation of cell proliferation, differentiation and motility. Members of this family, which include CD9, CD37, CD53, CD63, CD82 and TAPA-1, share significant sequence homology and an extracellular N-glycosylated domain, implicating these proteins as metastasis suppressors. Only three members of this family have been correlated with metastasis: CD9, CD63 and CD82, also known as KAI 1. KAI 1 is evolutionarily conserved and expressed in a broad range of human tissues, but exhibits reduced expression in human cell lines derived from metastatic prostate tumors. It has been suggested that decreased KAI 1 expression may be involved in the malignant progression of prostate and perhaps other cancers.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CD82 protein structure - BS7682 shown in red.