Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS7682 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CD82 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human CD82.
- Description
- The transmembrane 4 superfamily (TM4SF) is a family of leukocyte surface glycoproteins that presumably cross the cell membrane four times. These proteins may be involved in transmembrane signal transduction regulation of cell proliferation, differentiation and motility. Members of this family, which include CD9, CD37, CD53, CD63, CD82 and TAPA-1, share significant sequence homology and an extracellular N-glycosylated domain, implicating these proteins as metastasis suppressors. Only three members of this family have been correlated with metastasis: CD9, CD63 and CD82, also known as KAI 1. KAI 1 is evolutionarily conserved and expressed in a broad range of human tissues, but exhibits reduced expression in human cell lines derived from metastatic prostate tumors. It has been suggested that decreased KAI 1 expression may be involved in the malignant progression of prostate and perhaps other cancers.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of CD82 polyclonal antibody