Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 305311 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#305311, RRID:AB_314519
- Product name
- APC anti-human CD83
- Antibody type
- Monoclonal
- Antigen
- CD83
- Description
- CD83 is a 43 kD single chain type I glycoprotein also known as HB15. A member of the immunoglobulin superfamily, CD83 is expressed on a subset of dendritic cells, Langerhans cells, and weakly on activated lymphocytes. Although CD83 is thought to play a role in antigen presentation and/or lymphocyte activation, the precise function of this protein is unknown. CD83 is considered to be a useful marker for mature dendritic cells.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 25 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references Serum from patients with SLE instructs monocytes to promote IgG and IgA plasmablast differentiation.
Joo H, Coquery C, Xue Y, Gayet I, Dillon SR, Punaro M, Zurawski G, Banchereau J, Pascual V, Oh S
The Journal of experimental medicine 2012 Jul 2;209(7):1335-48
The Journal of experimental medicine 2012 Jul 2;209(7):1335-48
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Monocytes-derived dendritic cells (induced with GM-CSF+IL-4+TNF-?) stained with HB15e APC
- Conjugate
- Red dye