Antibody data

Product number
NBP2-75734-20ug - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal OCT2 Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. OCT2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. OCT2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of OCT2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of OCT2. Several studies of OCT2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for OCT2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
Reactivity
Human
Host
Mouse
Isotype
IgG
Vial size
20 ug
Concentration
0.2 mg/ml
Storage
Store at 4C.
POU2F2 protein structure - NBP2-75734-20ug shown in red.