Antibody data
- Antibody Data
- Antigen structure
- References [98]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
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- Product number
- 13801-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13801-1-AP, RRID:AB_2186881
- Product name
- PAI-1 antibody
- Antibody type
- Polyclonal
- Description
- PAI-1 antibody (Cat. #13801-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Adipose Mesenchymal Stem Cells Promote Wound Healing by Modulating Expression of SERPINE1 in Dermal Fibroblasts and Keratinocytes.
Diverse roles of SERPINE1 in regulating cellular proliferation and invasion.
Possible contribution of the STAT3 signaling pathway to disseminated intravascular coagulation (DIC) in mice with cecal ligation and puncture-induced sepsis.
From chronic gastritis to gastric cancer: Mendelian randomisation and multi-omics interrogation of leukaemia inhibitory factor receptor (LIFR), hepatocyte growth factor (HGF), serine protease inhibitor E1 (SERPINE1) and interleukin-10 receptor subunit beta (IL10RB).
Ovatodiolide overcomes cisplatin resistance in head and neck cancer by disrupting a novel oncogenic signature and cancer-associated fibroblast activation.
PAI-1 promotes thromboangiitis obliterans progression through NF-κB-NLRP3 pathway activation via HIF-1α-dependent signaling.
SERPINE1-Driven MAPK Activation Enhances Cuproptosis Resistance and Angiogenic Potential in Colorectal Cancer.
Identification of core cytotoxic T lymphocyte-related subtypes, establishment of a prognostic model, and analysis tumor microenvironment infiltration in HNSC.
Methionine drives lung adenocarcinoma progression via regulation of BACH1-SERPINE1.
Hypericin Nanoparticles-Associated Photodynamic Therapy Modulates the Biological Behavior of Hepatocellular Carcinoma by SERPINE1.
CircPRMT5, a Potential Salivary Biomarker, Facilitates the Progression of Head and Neck Squamous Cell Carcinoma via the IGF2BP3-SERPINE1 Pathway.
Integrated network pharmacology and experimental verification to reveal the mechanisms of curcumin in the treatment of colorectal cancer.
Shanling Jiangzhi Tea treats hyperuricemia by inhibition of COMT/MAOA signaling pathway and p53/SERPINE1/NLRP3 signaling pathway.
Proteomics of stress-induced cardiomyopathy: insights from differential expression, protein interaction networks, and functional pathway enrichment in an isoproterenol-induced TTC mouse model.
IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury.
Synergistic overcoming of cisplatin resistance in ovarian cancer by combined Astragalus Membranaceus and cisplatin treatment: network pharmacology and experimental validation.
Host cell and viral protease targets of human SERPINs identified by in silico docking.
Mechanism of action of Aloe vera against human papillomavirus-positive head and neck squamous cell carcinoma.
Isoimperatorin Reduces Synovial Inflammation and Fibrosis in Knee Osteoarthritis via the cAMP Signalling Pathway.
Peroxisome Proliferator-Activated Receptor Agonist IVA337 Alleviates Inflammation and Fibrosis in MASH by Restoring Lipid Homeostasis.
Vitamin C conveys geroprotection on primate ovaries.
Histone lactylation-induced GLI3 activation drives macrophage M1 polarization and exosomal SERPINE1 release in abdominal aortic aneurysm progression.
Repurposing of FDA-approved drugs by targeting SIRT2 to alleviate inflammatory response and kidney injury.
Identification of preventive biomarkers associated with circadian rhythms in traumatic brain injury-mediated depression: Expression of SERPINE1 protein and bioinformatics analysis.
RUNX1 promotes colorectal cancer progression by activating SERPINE1 transcription.
Mitomycin induced the senescence of alveolar epithelial cells by targeting peroxiredoxin I.
Inflammation-induced TET3/mir-3942 axis impedes the proliferation and invasion ability of trophoblast cells through destabilization of SERPINE1 in preeclampsia.
CRISPR screens and quantitative proteomics reveal remodeling of the aryl hydrocarbon receptor-driven proteome through PARP7 activity.
DHCR7 inhibition ameliorates MetALD and HCC in mice and human 3D liver spheroids.
A Sandwiched Patch for Prevention of Pelvic Adhesion After Uterine Operation.
Resolving the developmental mechanisms of cardiac microthrombosis of SARS-CoV-2 based on single-cell transcriptome analysis.
Effect of calcium concentration on metastasis of hepatocellular carcinoma cells cultured in alginate gel beads.
LARP6 regulates the mRNA translation of fibrogenic genes in liver fibrosis.
CMAP prediction and experimental validation of Forskolin as a podocyte protective and anti-proteinuric drug for nephrotoxic serum-treated mice.
3D-cultured DFAT spheroid-derived exosomes promote aged wound healing via modulation of the NF-κB/Serpine1 pathway.
Fatty acid synthesis promotes mtDNA release via ETS1-mediated oligomerization of VDAC1 facilitating endothelial dysfunction in sepsis-induced lung injury.
ETS1 suppresses hepatic stellate cell activation and liver fibrosis.
Identification of Shared Genes and Immune Profiling for Pathological Scar.
Integrative Multi-Omics Approaches Reveal Selectivity Profiles and Molecular Mechanisms of FIIN-2, a Covalent FGFR Inhibitor.
Orbital mesenchymal chondrosarcoma and its specific fusion gene HEY1-NCOA2.
Impact of Escherichia coli and Lipopolysaccharide on the MAPK Signaling Pathway, MMPs, TIMPs, and the uPA System in Bovine Mammary Epithelial Cells.
Mechanism of Zhenwu Decoction modulating TLR4/NF-κB/HIF-1α loop through miR-451 to delay renal fibrosis in type 2 CRS.
Interleukin-1 increases SERPINE1 expression in human granulosa-lutein cell via P50/P52 signaling pathways.
Urolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E-deficient mice.
Suppressing Expression of SERPINE1/PAI1 Through Activation of GPER1 Reduces Progression of Vulvar Carcinoma.
SETDB1 modulates the TGFβ response in Duchenne muscular dystrophy myotubes.
MiRNA-145-5p inhibits gastric cancer progression via the serpin family E member 1- extracellular signal-regulated kinase-1/2 axis.
Transcriptomics reveal a molecular signature in the progression of nonalcoholic steatohepatitis and identifies PAI‑1 and MMP‑9 as biomarkers in in vivo and in vitro studies.
Overexpression of Corin Ameliorates Kidney Fibrosis through Inhibition of Wnt/β-Catenin Signaling in Mice.
RUNX1 targeting AKT3 promotes alveolar hypercoagulation and fibrinolytic inhibition in LPS induced ARDS.
6-Gingerol ameliorates alveolar hypercoagulation and fibrinolytic inhibition in LPS-provoked ARDS via RUNX1/NF-κB signaling pathway.
Ginsenoside Rb1 prevents age-related endothelial senescence by modulating SIRT1/caveolin-1/enos signaling pathway.
Endothelial H(2)S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.
Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer.
A circular RNA activated by TGFβ promotes tumor metastasis through enhancing IGF2BP3-mediated PDPN mRNA stability.
PDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK pathway.
Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy.
Knockdown of G Protein-coupled Estrogen Receptor 1 (GPER1) Enhances Tumor-supportive Properties in Cervical Carcinoma Cells.
Novel Populations of Lung Capillary Endothelial Cells and Their Functional Significance.
miR-9 targeting RUNX1 improves LPS-induced alveolar hypercoagulation and fibrinolysis inhibition through NF-κB inactivation in ARDS.
RBM4 regulates cellular senescence via miR1244/SERPINE1 axis.
Exosomal circCNOT6L Regulates Astrocyte Apoptotic Signals Induced by Hypoxia Exposure Through miR99a-5p/SERPINE1 and Alleviates Ischemic Stroke Injury.
Derazantinib Inhibits the Bioactivity of Keloid Fibroblasts via FGFR Signaling.
A novel necroptosis-related gene index for predicting prognosis and a cold tumor immune microenvironment in stomach adenocarcinoma.
Identification of an unrecognized circRNA associated with development of renal fibrosis.
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho.
Elimination of senescent cells inhibits epithelial-mesenchymal transition of retinal pigment epithelial cells.
A SERPINE1-Based Immune Gene Signature Predicts Prognosis and Immunotherapy Response in Gastric Cancer.
Mesangial cell-derived tenascin-C contributes to mesangial cell proliferation and matrix protein production in IgA nephropathy.
Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration.
Krill Oil Turns Off TGF-β1 Profibrotic Signaling in the Prevention of Diabetic Nephropathy.
CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.
SIX5-activated LINC01468 promotes lung adenocarcinoma progression by recruiting SERBP1 to regulate SERPINE1 mRNA stability and recruiting USP5 to facilitate PAI1 protein deubiquitylation.
Loss of TARBP2 Drives the Progression of Hepatocellular Carcinoma via miR-145-SERPINE1 Axis.
Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling.
Aberrant elevation of GDF8 impairs granulosa cell glucose metabolism via upregulating SERPINE1 expression in patients with PCOS.
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
Systemic sclerosis biomarkers detection in the secretome of TGFβ1-activated primary human lung fibroblasts.
E4 engages uPAR and enolase-1 and activates urokinase to exert antifibrotic effects.
ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer.
Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
miR-18a Inhibits BMP4 and HIF-1α Normalizing Brain Arteriovenous Malformations.
A translational program that suppresses metabolism to shield the genome.
A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism.
Cross-Talk between Transforming Growth Factor-β and Periostin Can Be Targeted for Pulmonary Fibrosis.
Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway.
Transcriptome sequencing reveals fibrotic associated-genes involved in bovine mammary fibroblasts with Staphylococcus aureus.
Knockdown of TRIM27 expression suppresses the dysfunction of mesangial cells in lupus nephritis by FoxO1 pathway.
PAI-1 secreted from metastatic ovarian cancer cells triggers the tumor-promoting role of the mesothelium in a feedback loop to accelerate peritoneal dissemination.
Herba Artemisiae Capillaris Extract Prevents the Development of Streptozotocin-Induced Diabetic Nephropathy of Rat.
Changes in Corticotrope Gene Expression Upon Increased Expression of Peptidylglycine α-Amidating Monooxygenase.
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Hypoxia induces TFE3 expression in head and neck squamous cell carcinoma.
Development of a Biomimetic Chondroitin Sulfate-modified Hydrogel to Enhance the Metastasis of Tumor Cells.
Inhibition of mTOR reduce Stat3 and PAI related angiogenesis in salivary gland adenoid cystic carcinoma.
Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis.
Global secretome characterization of A549 human alveolar epithelial carcinoma cells during Mycoplasma pneumoniae infection.
Tryptase promotes atherosclerotic plaque haemorrhage in ApoE-/- mice.
Liang Y, Sun Q, Sun J, Xu M, Xu J, Yu Y
Stem cells international 2026;2026:5541440
Stem cells international 2026;2026:5541440
Diverse roles of SERPINE1 in regulating cellular proliferation and invasion.
Wang W, Zhao P, Wang T, Wu W, Li J, Huang Q, Mo J
International journal of oncology 2026 May;68(5)
International journal of oncology 2026 May;68(5)
Possible contribution of the STAT3 signaling pathway to disseminated intravascular coagulation (DIC) in mice with cecal ligation and puncture-induced sepsis.
Imbaby S, Machida T, Hattori K, Hiraide S, Yamamoto T, Kuroda A, Takahashi Y, Iizuka K, Yokoo H, Matsuda N, Hattori Y
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar;399(5):6609-6622
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar;399(5):6609-6622
From chronic gastritis to gastric cancer: Mendelian randomisation and multi-omics interrogation of leukaemia inhibitory factor receptor (LIFR), hepatocyte growth factor (HGF), serine protease inhibitor E1 (SERPINE1) and interleukin-10 receptor subunit beta (IL10RB).
Lu L, Li Q, Yang M, Peng H, Hu J, Chen J, Guo J
International journal of biological macromolecules 2026 Jan;337(Pt 2):149541
International journal of biological macromolecules 2026 Jan;337(Pt 2):149541
Ovatodiolide overcomes cisplatin resistance in head and neck cancer by disrupting a novel oncogenic signature and cancer-associated fibroblast activation.
Yang CH, Renantha RR, Hsu PC, Wu AT, Wu SY, Azizah N, Ritmaleni R, Chen JH, Lee JC, Fang CY, Lin KC
Journal of dental sciences 2026 Jan;21(1):282-293
Journal of dental sciences 2026 Jan;21(1):282-293
PAI-1 promotes thromboangiitis obliterans progression through NF-κB-NLRP3 pathway activation via HIF-1α-dependent signaling.
Xu X, Ge X, Ci H, Abulaihaiti M, Yang J, Li Y, Zhu F
Microvascular research 2026 Jan;163:104885
Microvascular research 2026 Jan;163:104885
SERPINE1-Driven MAPK Activation Enhances Cuproptosis Resistance and Angiogenic Potential in Colorectal Cancer.
Gao P, Li H, Luo J, Zhang C, Wei J, Li X, Ma H
Digestive diseases and sciences 2026 Feb 9;
Digestive diseases and sciences 2026 Feb 9;
Identification of core cytotoxic T lymphocyte-related subtypes, establishment of a prognostic model, and analysis tumor microenvironment infiltration in HNSC.
Jiang W, Liu Q, Chu H, Dai Y, Li Y, Wu C, Zuo N, Sun F, Hu X, Wei N, Fang Z, Hua H, Gao C, Liu S, Yang Q
Scientific reports 2026 Feb 18;16(1)
Scientific reports 2026 Feb 18;16(1)
Methionine drives lung adenocarcinoma progression via regulation of BACH1-SERPINE1.
Wen X, Hao S, Zhong M, Jiang P
Biochimica et biophysica acta. Molecular cell research 2026 Apr 17;1873(5):120151
Biochimica et biophysica acta. Molecular cell research 2026 Apr 17;1873(5):120151
Hypericin Nanoparticles-Associated Photodynamic Therapy Modulates the Biological Behavior of Hepatocellular Carcinoma by SERPINE1.
Yan X, Fan J, Qin W, Liao M, Li S, Suo L, Xie Y, Jiang X, Zou D, Liao W
International journal of nanomedicine 2025;20:3713-3730
International journal of nanomedicine 2025;20:3713-3730
CircPRMT5, a Potential Salivary Biomarker, Facilitates the Progression of Head and Neck Squamous Cell Carcinoma via the IGF2BP3-SERPINE1 Pathway.
Jiang S, Ou L, Wang Y, Su K, Chen Z, He L, Xu X, Cheng B, Xia J, Fan Z
International journal of nanomedicine 2025;20:1597-1613
International journal of nanomedicine 2025;20:1597-1613
Integrated network pharmacology and experimental verification to reveal the mechanisms of curcumin in the treatment of colorectal cancer.
Yuan Z, Hu J, Cai C, Liu F, Chen H, Zeng B
Frontiers in pharmacology 2025;16:1703562
Frontiers in pharmacology 2025;16:1703562
Shanling Jiangzhi Tea treats hyperuricemia by inhibition of COMT/MAOA signaling pathway and p53/SERPINE1/NLRP3 signaling pathway.
Chen HN, Wu HZ, Yang YF
Frontiers in endocrinology 2025;16:1623111
Frontiers in endocrinology 2025;16:1623111
Proteomics of stress-induced cardiomyopathy: insights from differential expression, protein interaction networks, and functional pathway enrichment in an isoproterenol-induced TTC mouse model.
Tian L, Liu B, Ren Y, Cui J, Pang Z
PeerJ 2025;13:e18984
PeerJ 2025;13:e18984
IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury.
Su H, Lin X, Paredong A, Yao C, Zhang Y, Geng M, Guan Y, Gong L, Jiang F, Lv Q, Shou S, Jin H
Frontiers in molecular biosciences 2025;12:1538526
Frontiers in molecular biosciences 2025;12:1538526
Synergistic overcoming of cisplatin resistance in ovarian cancer by combined Astragalus Membranaceus and cisplatin treatment: network pharmacology and experimental validation.
Wang F, Yue QF, Zhang Y, Lei FL
BMC complementary medicine and therapies 2025 Sep 30;25(1):337
BMC complementary medicine and therapies 2025 Sep 30;25(1):337
Host cell and viral protease targets of human SERPINs identified by in silico docking.
Rodriguez Galvan J, de Vries M, Belblidia S, Fisher A, Prescott RA, Crosse KM, Hearing P, Mangel WF, Duerr R, Dittmann M
The EMBO journal 2025 Oct;44(20):5755-5784
The EMBO journal 2025 Oct;44(20):5755-5784
Mechanism of action of Aloe vera against human papillomavirus-positive head and neck squamous cell carcinoma.
Zhu K, Han Y, Zhu Y, Zhu X, Huang S, Wang K
Oncology letters 2025 Oct;30(4):475
Oncology letters 2025 Oct;30(4):475
Isoimperatorin Reduces Synovial Inflammation and Fibrosis in Knee Osteoarthritis via the cAMP Signalling Pathway.
Jie L, Liu J, Zhu Z, Huang Z, Liu Y, Liu G, Shen X, Li Y, Shi X
Journal of cellular and molecular medicine 2025 Oct;29(19):e70880
Journal of cellular and molecular medicine 2025 Oct;29(19):e70880
Peroxisome Proliferator-Activated Receptor Agonist IVA337 Alleviates Inflammation and Fibrosis in MASH by Restoring Lipid Homeostasis.
Li N, Wu S, Li X, Yan M, Ding Y, Zhang L, Brenner DA, Liu X, Kisseleva T
The American journal of pathology 2025 Oct;195(10):1822-1838
The American journal of pathology 2025 Oct;195(10):1822-1838
Vitamin C conveys geroprotection on primate ovaries.
Jing Y, Lu H, Li J, He Z, Zhao L, Zhang C, Huang Z, Liu L, Sun S, Ma S, Rodriguez Esteban C, Fu X, Zhao G, Izpisua Belmonte JC, Zhang W, Qu J, Wang S, Liu GH
Cell stem cell 2025 Nov 6;32(11):1723-1740.e9
Cell stem cell 2025 Nov 6;32(11):1723-1740.e9
Histone lactylation-induced GLI3 activation drives macrophage M1 polarization and exosomal SERPINE1 release in abdominal aortic aneurysm progression.
Yuan K, Liu J, Chen G, Wang P, Wei L
Cell death discovery 2025 Nov 10;11(1):523
Cell death discovery 2025 Nov 10;11(1):523
Repurposing of FDA-approved drugs by targeting SIRT2 to alleviate inflammatory response and kidney injury.
Huang HJ, Lin YC, Ho LJ, Su RY, Liu WC, Chiu HW
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Nov 1;214:107296
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Nov 1;214:107296
Identification of preventive biomarkers associated with circadian rhythms in traumatic brain injury-mediated depression: Expression of SERPINE1 protein and bioinformatics analysis.
Cai Y, Huang G, Ren M, Zhang X, Yan T, Zhu L
International journal of biological macromolecules 2025 May;310(Pt 1):143229
International journal of biological macromolecules 2025 May;310(Pt 1):143229
RUNX1 promotes colorectal cancer progression by activating SERPINE1 transcription.
Yang Y, Deng S, Yin Q, Zhang T, Liu T, Wu D, Xu Y
Biochemical and biophysical research communications 2025 May 26;760:151732
Biochemical and biophysical research communications 2025 May 26;760:151732
Mitomycin induced the senescence of alveolar epithelial cells by targeting peroxiredoxin I.
Sun X, Wan X, Chen L, Cui Y, Chen X, Zhang J, Jiang X
Biochemical pharmacology 2025 Jun;236:116890
Biochemical pharmacology 2025 Jun;236:116890
Inflammation-induced TET3/mir-3942 axis impedes the proliferation and invasion ability of trophoblast cells through destabilization of SERPINE1 in preeclampsia.
Deng X, Zuo Q, Liu Y, Li M, Wu L, Jiang J, Rahman J, Sagnelli M, Zhang T, Sun L, Xu Y
Placenta 2025 Jun 26;167:193-203
Placenta 2025 Jun 26;167:193-203
CRISPR screens and quantitative proteomics reveal remodeling of the aryl hydrocarbon receptor-driven proteome through PARP7 activity.
Gorelik A, Paulo JA, Schroeter CB, Lad M, Shurr A, Mastrokalou C, Siddiqi S, Suyari O, Brognard J, Walter D, Matthews J, Palmer TM, Gygi SP, Ahel I
Proceedings of the National Academy of Sciences of the United States of America 2025 Jun 17;122(24):e2424985122
Proceedings of the National Academy of Sciences of the United States of America 2025 Jun 17;122(24):e2424985122
DHCR7 inhibition ameliorates MetALD and HCC in mice and human 3D liver spheroids.
Yamamoto G, Carvalho-Gontijo Weber R, Lee W, Zhang V, Jang H, Sakane S, Liu X, Kim HY, Brenner DA, Li N, Kisseleva T
JHEP reports : innovation in hepatology 2025 Jul;7(7):101415
JHEP reports : innovation in hepatology 2025 Jul;7(7):101415
A Sandwiched Patch for Prevention of Pelvic Adhesion After Uterine Operation.
Liang W, Chen D, Hou M, Yang W, Xie M, Zhong X
Journal of biomedical materials research. Part B, Applied biomaterials 2025 Jul;113(7):e35600
Journal of biomedical materials research. Part B, Applied biomaterials 2025 Jul;113(7):e35600
Resolving the developmental mechanisms of cardiac microthrombosis of SARS-CoV-2 based on single-cell transcriptome analysis.
Luo X, Zhang N, Liu Y, Du B, Wang X, Zhao T, Liu B, Zhao S, Qiu J, Wang G
Science China. Life sciences 2025 Jan;68(1):103-115
Science China. Life sciences 2025 Jan;68(1):103-115
Effect of calcium concentration on metastasis of hepatocellular carcinoma cells cultured in alginate gel beads.
Jia Y, Xu X, Liu Y, Shen H, Sun S, Sun G
Colloids and surfaces. B, Biointerfaces 2025 Jan;245:114201
Colloids and surfaces. B, Biointerfaces 2025 Jan;245:114201
LARP6 regulates the mRNA translation of fibrogenic genes in liver fibrosis.
Kim HY, Mizrahi O, Lee W, Rosenthal SB, Han C, Yee BA, Blue SM, Diaz J, Jonnalagadda J, Hokutan K, Jang H, Ma CT, Bobkov A, Sergienko E, Jackson MR, Stefanovic B, Kisseleva T, Yeo GW, Brenner DA
bioRxiv : the preprint server for biology 2025 Jan 18;
bioRxiv : the preprint server for biology 2025 Jan 18;
CMAP prediction and experimental validation of Forskolin as a podocyte protective and anti-proteinuric drug for nephrotoxic serum-treated mice.
Huang W, Yu P, Zhao X, Shi J, Jin X, Jin R, Dong S, Xia W, Zhu X, Wang J, Zhang H, Ren L, Shi S
Biochemical pharmacology 2025 Feb;232:116727
Biochemical pharmacology 2025 Feb;232:116727
3D-cultured DFAT spheroid-derived exosomes promote aged wound healing via modulation of the NF-κB/Serpine1 pathway.
Ma X, Wei W, Zeng H, Dong M
Tissue & cell 2025 Dec;97:103049
Tissue & cell 2025 Dec;97:103049
Fatty acid synthesis promotes mtDNA release via ETS1-mediated oligomerization of VDAC1 facilitating endothelial dysfunction in sepsis-induced lung injury.
He S, Pan T, Tian R, He Q, Cheng D, Qu H, Li R, Tan R
Cell death and differentiation 2025 Dec;32(12):2177-2192
Cell death and differentiation 2025 Dec;32(12):2177-2192
ETS1 suppresses hepatic stellate cell activation and liver fibrosis.
Lee W, Liu X, Rosenthal SB, Miciano C, Sakane S, Hokutan K, Dhar D, Kim HY, Brenner DA, Kisseleva T
JCI insight 2025 Dec 22;10(24)
JCI insight 2025 Dec 22;10(24)
Identification of Shared Genes and Immune Profiling for Pathological Scar.
Dou S, Deng Y, Wang D, Liu W
Journal of burn care & research : official publication of the American Burn Association 2025 Aug 30;46(4):870-885
Journal of burn care & research : official publication of the American Burn Association 2025 Aug 30;46(4):870-885
Integrative Multi-Omics Approaches Reveal Selectivity Profiles and Molecular Mechanisms of FIIN-2, a Covalent FGFR Inhibitor.
Fu Y, Zhu D, Chen X, Qu L, Guo M, Zhang S, Xu G, Chen Z, Li M, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2412578
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2412578
Orbital mesenchymal chondrosarcoma and its specific fusion gene HEY1-NCOA2.
Lin JQ, Liu X, Zhao JZ, Wang Q, Zhu LM, Lin TT
BMC ophthalmology 2025 Apr 29;25(1):258
BMC ophthalmology 2025 Apr 29;25(1):258
Impact of Escherichia coli and Lipopolysaccharide on the MAPK Signaling Pathway, MMPs, TIMPs, and the uPA System in Bovine Mammary Epithelial Cells.
Zhang Y, Ding Y, Liang J, Zhang K, Su H, Wang D, Zhang M, Zhao F, Sun Z, Wu Z, Wang F, Cao G, Zhang Y
International journal of molecular sciences 2025 Apr 20;26(8)
International journal of molecular sciences 2025 Apr 20;26(8)
Mechanism of Zhenwu Decoction modulating TLR4/NF-κB/HIF-1α loop through miR-451 to delay renal fibrosis in type 2 CRS.
Xu X, Wang Y, Song Q, Zheng H, Lv J, Fu Z, Mao X, Li Y, Wu H, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155632
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155632
Interleukin-1 increases SERPINE1 expression in human granulosa-lutein cell via P50/P52 signaling pathways.
Xiang Y, Liu S, Wan S, Chen Q, Song Y, Feng G, Zhang X, Bai L, Zhu Y
Molecular and cellular endocrinology 2024 Sep 15;591:112274
Molecular and cellular endocrinology 2024 Sep 15;591:112274
Urolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E-deficient mice.
Xu MY, Xu JJ, Kang LJ, Liu ZH, Su MM, Zhao WQ, Wang ZH, Sun L, Xiao JB, Evans PC, Tian XY, Wang L, Huang Y, Liang XM, Weng JP, Xu SW
Acta pharmacologica Sinica 2024 Nov;45(11):2277-2289
Acta pharmacologica Sinica 2024 Nov;45(11):2277-2289
Suppressing Expression of SERPINE1/PAI1 Through Activation of GPER1 Reduces Progression of Vulvar Carcinoma.
Doelker T, Gallwas J, Gründker C
Cancer genomics & proteomics 2024 Nov-Dec;21(6):566-579
Cancer genomics & proteomics 2024 Nov-Dec;21(6):566-579
SETDB1 modulates the TGFβ response in Duchenne muscular dystrophy myotubes.
Granados A, Zamperoni M, Rapone R, Moulin M, Boyarchuk E, Bouyioukos C, Del Maestro L, Joliot V, Negroni E, Mohamed M, Piquet S, Bigot A, Le Grand F, Albini S, Ait-Si-Ali S
Science advances 2024 May 3;10(18):eadj8042
Science advances 2024 May 3;10(18):eadj8042
MiRNA-145-5p inhibits gastric cancer progression via the serpin family E member 1- extracellular signal-regulated kinase-1/2 axis.
Bai HX, Qiu XM, Xu CH, Guo JQ
World journal of gastrointestinal oncology 2024 May 15;16(5):2123-2140
World journal of gastrointestinal oncology 2024 May 15;16(5):2123-2140
Transcriptomics reveal a molecular signature in the progression of nonalcoholic steatohepatitis and identifies PAI‑1 and MMP‑9 as biomarkers in in vivo and in vitro studies.
Zhao Y, Yakufu M, Ma C, Wang B, Yang J, Hu J
Molecular medicine reports 2024 Jan;29(1)
Molecular medicine reports 2024 Jan;29(1)
Overexpression of Corin Ameliorates Kidney Fibrosis through Inhibition of Wnt/β-Catenin Signaling in Mice.
Su X, Li S, Zhang Y, Tie X, Feng R, Guo X, Qiao X, Wang L
The American journal of pathology 2024 Jan;194(1):101-120
The American journal of pathology 2024 Jan;194(1):101-120
RUNX1 targeting AKT3 promotes alveolar hypercoagulation and fibrinolytic inhibition in LPS induced ARDS.
Xiao C, Liu J, Cheng Y, Wu Y, Li Q, Chen X, Yuan J, Dong Q, Li L, Liu Y, Shen F
Respiratory research 2024 Jan 24;25(1):54
Respiratory research 2024 Jan 24;25(1):54
6-Gingerol ameliorates alveolar hypercoagulation and fibrinolytic inhibition in LPS-provoked ARDS via RUNX1/NF-κB signaling pathway.
Li Q, Xiao C, Gu J, Chen X, Yuan J, Li S, Li W, Gao D, Li L, Liu Y, Shen F
International immunopharmacology 2024 Feb 15;128:111459
International immunopharmacology 2024 Feb 15;128:111459
Ginsenoside Rb1 prevents age-related endothelial senescence by modulating SIRT1/caveolin-1/enos signaling pathway.
Zhou B, Sh G, Xie D, Zhao X, Hao B, Liu D, Wang M, Wu L, Lin L, Qian X
Heliyon 2024 Feb 15;10(3):e24586
Heliyon 2024 Feb 15;10(3):e24586
Endothelial H(2)S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.
Chen X, Wang H, Wu C, Li X, Huang X, Ren Y, Pu Q, Cao Z, Tang X, Ding BS
Redox biology 2024 Apr;70:103038
Redox biology 2024 Apr;70:103038
Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer.
Dashzeveg NK, Jia Y, Zhang Y, Gerratana L, Patel P, Shajahan A, Dandar T, Ramos EK, Almubarak HF, Adorno-Cruz V, Taftaf R, Schuster EJ, Scholten D, Sokolowski MT, Reduzzi C, El-Shennawy L, Hoffmann AD, Manai M, Zhang Q, D'Amico P, Azadi P, Colley KJ, Platanias LC, Shah AN, Gradishar WJ, Cristofanilli M, Muller WA, Cobb BA, Liu H
Cancer discovery 2023 Sep 6;13(9):2050-2071
Cancer discovery 2023 Sep 6;13(9):2050-2071
A circular RNA activated by TGFβ promotes tumor metastasis through enhancing IGF2BP3-mediated PDPN mRNA stability.
Li K, Guo J, Ming Y, Chen S, Zhang T, Ma H, Fu X, Wang J, Liu W, Peng Y
Nature communications 2023 Oct 28;14(1):6876
Nature communications 2023 Oct 28;14(1):6876
PDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK pathway.
Ma Z, Ding Y, Ding X, Mou H, Mo R, Tan Q
Cell death discovery 2023 Nov 25;9(1):424
Cell death discovery 2023 Nov 25;9(1):424
Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy.
Wang Y, He X, Xue M, Sun W, He Q, Jin J
Free radical research 2023 May-Jun;57(6-12):413-429
Free radical research 2023 May-Jun;57(6-12):413-429
Knockdown of G Protein-coupled Estrogen Receptor 1 (GPER1) Enhances Tumor-supportive Properties in Cervical Carcinoma Cells.
Ruckriegl S, Loris J, Wert K, Bauerschmitz G, Gallwas J, Gründker C
Cancer genomics & proteomics 2023 May-Jun;20(3):281-297
Cancer genomics & proteomics 2023 May-Jun;20(3):281-297
Novel Populations of Lung Capillary Endothelial Cells and Their Functional Significance.
James J, Dekan A, Niihori M, McClain N, Varghese M, Bharti D, Lawal OS, Padilla-Rodrigez M, Yi D, Dai Z, Gusev O, Rafikova O, Rafikov R
Research square 2023 May 3;
Research square 2023 May 3;
miR-9 targeting RUNX1 improves LPS-induced alveolar hypercoagulation and fibrinolysis inhibition through NF-κB inactivation in ARDS.
Xiao C, Li Q, Xiao J, Chen X, Yuan J, Li S, Li W, Gao D, Li L, Liu Y, Shen F
International immunopharmacology 2023 Jul;120:110318
International immunopharmacology 2023 Jul;120:110318
RBM4 regulates cellular senescence via miR1244/SERPINE1 axis.
Wang L, Zhang X, Sheng J, Chen L, Zhi L, Zheng Q, Qi Y, Wang L, Zhang J, Zhao J, Wang Y, Liu SX, Sun MZ, Zhang W
Cell death & disease 2023 Jan 13;14(1):27
Cell death & disease 2023 Jan 13;14(1):27
Exosomal circCNOT6L Regulates Astrocyte Apoptotic Signals Induced by Hypoxia Exposure Through miR99a-5p/SERPINE1 and Alleviates Ischemic Stroke Injury.
He W, Gu L, Yang J, Zhang R, Long J, Peng W, Liang B, Zhu L, Lv M, Nan A, Su L
Molecular neurobiology 2023 Dec;60(12):7118-7135
Molecular neurobiology 2023 Dec;60(12):7118-7135
Derazantinib Inhibits the Bioactivity of Keloid Fibroblasts via FGFR Signaling.
Xu S, Zhu Y, Wang P, Qi S, Shu B
Biomedicines 2023 Dec 5;11(12)
Biomedicines 2023 Dec 5;11(12)
A novel necroptosis-related gene index for predicting prognosis and a cold tumor immune microenvironment in stomach adenocarcinoma.
Khan M, Lin J, Wang B, Chen C, Huang Z, Tian Y, Yuan Y, Bu J
Frontiers in immunology 2022;13:968165
Frontiers in immunology 2022;13:968165
Identification of an unrecognized circRNA associated with development of renal fibrosis.
Zhu Y, Yan W, Xu S, Yu X, Sun S, Zhang S, Zhao R, Tao J, Li Y, Li C
Frontiers in genetics 2022;13:964840
Frontiers in genetics 2022;13:964840
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho.
Zhou W, Chen MM, Liu HL, Si ZL, Wu WH, Jiang H, Wang LX, Vaziri ND, An XF, Su K, Chen C, Tan NH, Zhang ZH
Acta pharmacologica Sinica 2022 Oct;43(10):2609-2623
Acta pharmacologica Sinica 2022 Oct;43(10):2609-2623
Elimination of senescent cells inhibits epithelial-mesenchymal transition of retinal pigment epithelial cells.
Gao F, Wang L, Wu B, Ou Q, Tian H, Xu J, Jin C, Zhang J, Wang J, Lu L, Xu GT
Experimental eye research 2022 Oct;223:109207
Experimental eye research 2022 Oct;223:109207
A SERPINE1-Based Immune Gene Signature Predicts Prognosis and Immunotherapy Response in Gastric Cancer.
Xu X, Zhang L, Qian Y, Fang Q, Xiao Y, Chen G, Cai G, Abula A, Wang Z, Zhai E, Chen J, Cai S, Wu H
Pharmaceuticals (Basel, Switzerland) 2022 Nov 14;15(11)
Pharmaceuticals (Basel, Switzerland) 2022 Nov 14;15(11)
Mesangial cell-derived tenascin-C contributes to mesangial cell proliferation and matrix protein production in IgA nephropathy.
Yan M, Liu S, Zhang M, Lai L, Xie Q, Hao CM
Nephrology (Carlton, Vic.) 2022 May;27(5):458-466
Nephrology (Carlton, Vic.) 2022 May;27(5):458-466
Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration.
Guo Y, Chomiak AA, Hong Y, Lowe CC, Kopsidas CA, Chan WC, Andrade J, Pan H, Zhou X, Monuki ES, Feng Y
iScience 2022 Jul 15;25(7):104519
iScience 2022 Jul 15;25(7):104519
Krill Oil Turns Off TGF-β1 Profibrotic Signaling in the Prevention of Diabetic Nephropathy.
Sun X, Yang Y, Sun X, Meng H, Hao W, Yin J, Ma F, Guo X, Du L, Sun L, Wu H
Journal of agricultural and food chemistry 2022 Aug 17;70(32):9865-9876
Journal of agricultural and food chemistry 2022 Aug 17;70(32):9865-9876
CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.
Cui H, Xie N, Banerjee S, Dey T, Liu RM, Antony VB, Sanders YY, Adams TS, Gomez JL, Thannickal VJ, Kaminski N, Liu G
American journal of respiratory and critical care medicine 2022 Aug 15;206(4):459-475
American journal of respiratory and critical care medicine 2022 Aug 15;206(4):459-475
SIX5-activated LINC01468 promotes lung adenocarcinoma progression by recruiting SERBP1 to regulate SERPINE1 mRNA stability and recruiting USP5 to facilitate PAI1 protein deubiquitylation.
Yuan Y, Zhou D, Chen F, Yang Z, Gu W, Zhang K
Cell death & disease 2022 Apr 6;13(4):312
Cell death & disease 2022 Apr 6;13(4):312
Loss of TARBP2 Drives the Progression of Hepatocellular Carcinoma via miR-145-SERPINE1 Axis.
Li LM, Chen C, Ran RX, Huang JT, Sun HL, Zeng C, Zhang Z, Zhang W, Liu SM
Frontiers in oncology 2021;11:620912
Frontiers in oncology 2021;11:620912
Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling.
Xu X, Sun X, Wan X, Chen X, Jiang X
Toxicology letters 2021 Nov 1;352:61-69
Toxicology letters 2021 Nov 1;352:61-69
Aberrant elevation of GDF8 impairs granulosa cell glucose metabolism via upregulating SERPINE1 expression in patients with PCOS.
Bai L, Wang W, Xiang Y, Wang S, Wan S, Zhu Y
Molecular therapy. Nucleic acids 2021 Mar 5;23:294-309
Molecular therapy. Nucleic acids 2021 Mar 5;23:294-309
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
Miao Z, Ding Y, Bi Y, Chen M, Cao X, Wang F
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2021 Jun;54(3):411-419
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2021 Jun;54(3):411-419
Systemic sclerosis biomarkers detection in the secretome of TGFβ1-activated primary human lung fibroblasts.
Kendall RT, Renaud L, Baatz JE, Malaab M, Nguyen XX, Feghali-Bostwick CA
Journal of proteomics 2021 Jun 30;242:104243
Journal of proteomics 2021 Jun 30;242:104243
E4 engages uPAR and enolase-1 and activates urokinase to exert antifibrotic effects.
Sharma S, Watanabe T, Nishimoto T, Takihara T, Mlakar L, Nguyen XX, Sanderson M, Su Y, Chambers RA, Feghali-Bostwick C
JCI insight 2021 Dec 22;6(24)
JCI insight 2021 Dec 22;6(24)
ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer.
Taftaf R, Liu X, Singh S, Jia Y, Dashzeveg NK, Hoffmann AD, El-Shennawy L, Ramos EK, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Zhang Y, Davis AA, Reduzzi C, Cao Y, D'Amico P, Shen Y, Cristofanilli M, Muller WA, Varadan V, Liu H
Nature communications 2021 Aug 11;12(1):4867
Nature communications 2021 Aug 11;12(1):4867
Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
Mao Y, Li W, Hua B, Gu X, Pan W, Chen Q, Xu B, Wang Z, Lu C
BioMed research international 2020;2020:2406159
BioMed research international 2020;2020:2406159
miR-18a Inhibits BMP4 and HIF-1α Normalizing Brain Arteriovenous Malformations.
Marín-Ramos NI, Thein TZ, Ghaghada KB, Chen TC, Giannotta SL, Hofman FM
Circulation research 2020 Oct 9;127(9):e210-e231
Circulation research 2020 Oct 9;127(9):e210-e231
A translational program that suppresses metabolism to shield the genome.
Balukoff NC, Ho JJD, Theodoridis PR, Wang M, Bokros M, Llanio LM, Krieger JR, Schatz JH, Lee S
Nature communications 2020 Nov 13;11(1):5755
Nature communications 2020 Nov 13;11(1):5755
A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism.
Ho JJD, Balukoff NC, Theodoridis PR, Wang M, Krieger JR, Schatz JH, Lee S
Nature communications 2020 May 29;11(1):2677
Nature communications 2020 May 29;11(1):2677
Cross-Talk between Transforming Growth Factor-β and Periostin Can Be Targeted for Pulmonary Fibrosis.
Nanri Y, Nunomura S, Terasaki Y, Yoshihara T, Hirano Y, Yokosaki Y, Yamaguchi Y, Feghali-Bostwick C, Ajito K, Murakami S, Conway SJ, Izuhara K
American journal of respiratory cell and molecular biology 2020 Feb;62(2):204-216
American journal of respiratory cell and molecular biology 2020 Feb;62(2):204-216
Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway.
Chen ZQ, Sun XH, Li XJ, Xu ZC, Yang Y, Lin ZY, Xiao HM, Zhang M, Quan SJ, Huang HQ
Acta pharmacologica Sinica 2020 Dec;41(12):1587-1596
Acta pharmacologica Sinica 2020 Dec;41(12):1587-1596
Transcriptome sequencing reveals fibrotic associated-genes involved in bovine mammary fibroblasts with Staphylococcus aureus.
Miao Z, Ding Y, Zhao N, Chen X, Cheng H, Wang J, Liu Y, Wang F
The international journal of biochemistry & cell biology 2020 Apr;121:105696
The international journal of biochemistry & cell biology 2020 Apr;121:105696
Knockdown of TRIM27 expression suppresses the dysfunction of mesangial cells in lupus nephritis by FoxO1 pathway.
Liu J, Feng X, Tian Y, Wang K, Gao F, Yang L, Li H, Tian Y, Yang R, Zhao L, Miao X, Huang J, Liu Q, Zhang W, Li Y, Wang C, Duan H, Liu S
Journal of cellular physiology 2019 Jul;234(7):11555-11566
Journal of cellular physiology 2019 Jul;234(7):11555-11566
PAI-1 secreted from metastatic ovarian cancer cells triggers the tumor-promoting role of the mesothelium in a feedback loop to accelerate peritoneal dissemination.
Peng Y, Kajiyama H, Yuan H, Nakamura K, Yoshihara M, Yokoi A, Fujikake K, Yasui H, Yoshikawa N, Suzuki S, Senga T, Shibata K, Kikkawa F
Cancer letters 2019 Feb 1;442:181-192
Cancer letters 2019 Feb 1;442:181-192
Herba Artemisiae Capillaris Extract Prevents the Development of Streptozotocin-Induced Diabetic Nephropathy of Rat.
Geng J, Yu X, Liu C, Sun C, Guo M, Li Z, Jin Y, Zou Y, Yu J
Evidence-based complementary and alternative medicine : eCAM 2018;2018:5180165
Evidence-based complementary and alternative medicine : eCAM 2018;2018:5180165
Changes in Corticotrope Gene Expression Upon Increased Expression of Peptidylglycine α-Amidating Monooxygenase.
Mains RE, Blaby-Haas C, Rheaume BA, Eipper BA
Endocrinology 2018 Jul 1;159(7):2621-2639
Endocrinology 2018 Jul 1;159(7):2621-2639
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Sun D, Liu Y, Wang H, Deng F, Zhang Y, Zhao S, Ma X, Wu H, Sun G
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
Hypoxia induces TFE3 expression in head and neck squamous cell carcinoma.
Sun ZJ, Yu GT, Huang CF, Bu LL, Liu JF, Ma SR, Zhang WF, Liu B, Zhang L
Oncotarget 2016 Mar 8;7(10):11651-63
Oncotarget 2016 Mar 8;7(10):11651-63
Development of a Biomimetic Chondroitin Sulfate-modified Hydrogel to Enhance the Metastasis of Tumor Cells.
Liu Y, Wang S, Sun D, Liu Y, Liu Y, Wang Y, Liu C, Wu H, Lv Y, Ren Y, Guo X, Sun G, Ma X
Scientific reports 2016 Jul 19;6:29858
Scientific reports 2016 Jul 19;6:29858
Inhibition of mTOR reduce Stat3 and PAI related angiogenesis in salivary gland adenoid cystic carcinoma.
Yu GT, Bu LL, Zhao YY, Liu B, Zhang WF, Zhao YF, Zhang L, Sun ZJ
American journal of cancer research 2014;4(6):764-75
American journal of cancer research 2014;4(6):764-75
Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis.
Liu Z, Gao Y, Hao F, Lou X, Zhang X, Li Y, Wu D, Xiao T, Yang L, Li Q, Qiu X, Wang E
Molecular biology reports 2014 Nov;41(11):7507-23
Molecular biology reports 2014 Nov;41(11):7507-23
Global secretome characterization of A549 human alveolar epithelial carcinoma cells during Mycoplasma pneumoniae infection.
Li S, Li X, Wang Y, Yang J, Chen Z, Shan S
BMC microbiology 2014 Feb 7;14:27
BMC microbiology 2014 Feb 7;14:27
Tryptase promotes atherosclerotic plaque haemorrhage in ApoE-/- mice.
Zhi X, Xu C, Zhang H, Tian D, Li X, Ning Y, Yin L
PloS one 2013;8(4):e60960
PloS one 2013;8(4):e60960
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 13801-1-AP(SERPINE1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- IP Result of anti-SERPINE1 (IP:13801-1-AP, 3ug; Detection:13801-1-AP 1:300) with SH-SY5Y cells lysate 2000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 13801-1-AP(SERPINE1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The PAI-1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PAI-1. This antibody recognizes human,mouse,rat antigen. The PAI-1 antibody has been validated for the following applications: ELISA, IHC, WB, IP analysis.