Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NBP1-19773 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-19773, RRID:AB_1642775
- Product name
- Rabbit Polyclonal Serpin E1/PAI-1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. PAI-1 (N315) pAb detects endogenous levels of PAI-1 protein.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Non-invasive detection of local tissue responses to predict pressure ulcer development in mouse models.
Low-Intensity Focused Ultrasound-Responsive Phase-Transitional Nanoparticles for Thrombolysis without Vascular Damage: A Synergistic Nonpharmaceutical Strategy.
Achyranthes bidentata polypeptide k improves long-term neurological outcomes through reducing downstream microvascular thrombosis in experimental ischemic stroke.
TDP-43 knockdown causes innate immune activation via protein kinase R in astrocytes.
VHL status regulates transforming growth factor-β signaling pathways in renal cell carcinoma.
BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor.
Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome.
Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits.
Transforming growth factor-β promotes aggressiveness and invasion of clear cell renal cell carcinoma.
The use of external mesh reinforcement to reduce intimal hyperplasia and preserve the structure of human saphenous veins.
Urokinase, urokinase receptor, and plasminogen activator inhibitor-1 expression on podocytes in immunoglobulin A glomerulonephritis.
Let-7g improves multiple endothelial functions through targeting transforming growth factor-beta and SIRT-1 signaling.
Role of hemodynamic forces in the ex vivo arterialization of human saphenous veins.
Atorvastatin-loaded hydrogel affects the smooth muscle cells of human veins.
Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotype.
Kimura N, Nakagami G, Minematsu T, Sanada H
Journal of tissue viability 2020 Feb;29(1):51-57
Journal of tissue viability 2020 Feb;29(1):51-57
Low-Intensity Focused Ultrasound-Responsive Phase-Transitional Nanoparticles for Thrombolysis without Vascular Damage: A Synergistic Nonpharmaceutical Strategy.
Zhong Y, Zhang Y, Xu J, Zhou J, Liu J, Ye M, Zhang L, Qiao B, Wang ZG, Ran HT, Guo D
ACS nano 2019 Mar 26;13(3):3387-3403
ACS nano 2019 Mar 26;13(3):3387-3403
Achyranthes bidentata polypeptide k improves long-term neurological outcomes through reducing downstream microvascular thrombosis in experimental ischemic stroke.
Cheng Q, Tong F, Shen Y, He C, Wang C, Ding F
Brain research 2019 Mar 1;1706:166-176
Brain research 2019 Mar 1;1706:166-176
TDP-43 knockdown causes innate immune activation via protein kinase R in astrocytes.
LaRocca TJ, Mariani A, Watkins LR, Link CD
Neurobiology of disease 2019 Dec;132:104514
Neurobiology of disease 2019 Dec;132:104514
VHL status regulates transforming growth factor-β signaling pathways in renal cell carcinoma.
Mallikarjuna P, Sitaram RT, Landström M, Ljungberg B
Oncotarget 2018 Mar 27;9(23):16297-16310
Oncotarget 2018 Mar 27;9(23):16297-16310
BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor.
Priyadarshini R, Hussain M, Attri P, Kaur E, Tripathi V, Priya S, Dhapola P, Saha D, Madhavan V, Chowdhury S, Sengupta S
Cell reports 2018 Jul 24;24(4):947-961.e7
Cell reports 2018 Jul 24;24(4):947-961.e7
Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome.
Hiebert P, Wietecha MS, Cangkrama M, Haertel E, Mavrogonatou E, Stumpe M, Steenbock H, Grossi S, Beer HD, Angel P, Brinckmann J, Kletsas D, Dengjel J, Werner S
Developmental cell 2018 Jul 16;46(2):145-161.e10
Developmental cell 2018 Jul 16;46(2):145-161.e10
Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits.
Gerenu G, Martisova E, Ferrero H, Carracedo M, Rantamäki T, Ramirez MJ, Gil-Bea FJ
Biochimica et biophysica acta. Molecular basis of disease 2017 Apr;1863(4):991-1001
Biochimica et biophysica acta. Molecular basis of disease 2017 Apr;1863(4):991-1001
Transforming growth factor-β promotes aggressiveness and invasion of clear cell renal cell carcinoma.
Sitaram RT, Mallikarjuna P, Landström M, Ljungberg B
Oncotarget 2016 Jun 14;7(24):35917-35931
Oncotarget 2016 Jun 14;7(24):35917-35931
The use of external mesh reinforcement to reduce intimal hyperplasia and preserve the structure of human saphenous veins.
Longchamp A, Alonso F, Dubuis C, Allagnat F, Berard X, Meda P, Saucy F, Corpataux JM, Déglise S, Haefliger JA
Biomaterials 2014 Mar;35(9):2588-99
Biomaterials 2014 Mar;35(9):2588-99
Urokinase, urokinase receptor, and plasminogen activator inhibitor-1 expression on podocytes in immunoglobulin A glomerulonephritis.
Lee JH, Oh MH, Park JS, Na GJ, Gil HW, Yang JO, Lee EY, Hong SY
The Korean journal of internal medicine 2014 Mar;29(2):176-82
The Korean journal of internal medicine 2014 Mar;29(2):176-82
Let-7g improves multiple endothelial functions through targeting transforming growth factor-beta and SIRT-1 signaling.
Liao YC, Wang YS, Guo YC, Lin WL, Chang MH, Juo SH
Journal of the American College of Cardiology 2014 Apr 29;63(16):1685-94
Journal of the American College of Cardiology 2014 Apr 29;63(16):1685-94
Role of hemodynamic forces in the ex vivo arterialization of human saphenous veins.
Berard X, Déglise S, Alonso F, Saucy F, Meda P, Bordenave L, Corpataux JM, Haefliger JA
Journal of vascular surgery 2013 May;57(5):1371-82
Journal of vascular surgery 2013 May;57(5):1371-82
Atorvastatin-loaded hydrogel affects the smooth muscle cells of human veins.
Dubuis C, May L, Alonso F, Luca L, Mylonaki I, Meda P, Delie F, Jordan O, Déglise S, Corpataux JM, Saucy F, Haefliger JA
The Journal of pharmacology and experimental therapeutics 2013 Dec;347(3):574-81
The Journal of pharmacology and experimental therapeutics 2013 Dec;347(3):574-81
Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotype.
Cao Y, Szabolcs A, Dutta SK, Yaqoob U, Jagavelu K, Wang L, Leof EB, Urrutia RA, Shah VH, Mukhopadhyay D
The Journal of biological chemistry 2010 Oct 8;285(41):31840-8
The Journal of biological chemistry 2010 Oct 8;285(41):31840-8
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Serpin E1/PAI-1 Antibody [NBP1-19773] - Extracts from Jurkat cells.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Serpin E1/PAI-1 Antibody [NBP1-19773] - Staining of PAI1/Serpine 1 in mouse pancreas.