Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 12118-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12118-1-AP, RRID:AB_10664925
- Product name
- ETS1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ETS1 antibody (Cat. #12118-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Elucidate senescence-related gene signature and immune infiltration landscape in abdominal aortic aneurysm.
IL-22/IL-22R signaling attenuates mitochondrial damage in PCOS by modulating granulosa cell lipid metabolism through ETS1.
ZBP1 Mediates Renal Tubular Injury in Diabetic Nephropathy Through RIPK3-mediated Necroptosis.
miR-495-3p promotes chronic obstructive pulmonary disease by activating ferroptosis in lung epithelial cells through regulation of the ETS1/GPX4 axis.
H3K18 lactylation-mediated Ythdf2 activation restrains mouse female germline stem cell proliferation via promoting Ets1 mRNA degradation.
PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1.
Anoikis-related biomarkers PARP1 and SDCBP as diagnostic and therapeutic targets for asthma.
HDAC8 Enhances the Function of HIF-2α by Deacetylating ETS1 to Decrease the Sensitivity of TKIs in ccRCC.
Disruption of blood-brain barrier and endothelial-to-mesenchymal transition are attenuated by Astragalus polysaccharides mediated through upregulation of ETS1 expression in experimental autoimmune encephalomyelitis.
Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.
Cellular senescence-Related genes define the immune microenvironment and molecular characteristics in severe asthma patients.
METTL14 promotes neuroblastoma formation by inhibiting YWHAH via an m6A-YTHDF1-dependent mechanism.
Inhibition of Foxp3 expression in the placenta of mice infected intraperitoneally by toxoplasma gondii tachyzoites: insights into the PPARγ/miR-7b-5p/Sp1 signaling pathway.
Mutation of the ETS1 3'UTR interacts with miR-216a-3p to regulate granulosa cell apoptosis in sheep.
HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.
The RNF26/CBX7 axis modulates the TNF pathway to promote cell proliferation and regulate sensitivity to TKIs in ccRCC.
The histone demthylase KDM3A protects the myocardium from ischemia/reperfusion injury via promotion of ETS1 expression.
rSjP40 Inhibited the Activity of Collagen Type I Promoter via Ets-1 in HSCs.
HIV reprograms host m(6)Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1.
p120 inhibits LPS/TNFα-induced endothelial Ang2 synthesis and release in an NF-κB independent fashion.
DOT1L promotes angiogenesis through cooperative regulation of VEGFR2 with ETS-1.
Li J, Ying R, Luo J, Guo X, Zhang M
PloS one 2026;21(1):e0340976
PloS one 2026;21(1):e0340976
IL-22/IL-22R signaling attenuates mitochondrial damage in PCOS by modulating granulosa cell lipid metabolism through ETS1.
Luo M, Chen Y, Chen H, Wen Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Mar 17;75(1)
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Mar 17;75(1)
ZBP1 Mediates Renal Tubular Injury in Diabetic Nephropathy Through RIPK3-mediated Necroptosis.
Hu Z, Ma Y, Wang Y, Wang J, Liu X, Chen C, Zhu W, Qi X, Wu Y
Inflammation 2026 Jan 3;49(1):24
Inflammation 2026 Jan 3;49(1):24
miR-495-3p promotes chronic obstructive pulmonary disease by activating ferroptosis in lung epithelial cells through regulation of the ETS1/GPX4 axis.
Chen H, Tu Y, Wang L, Zhu S
Molecular biology reports 2026 Apr 25;53(1)
Molecular biology reports 2026 Apr 25;53(1)
H3K18 lactylation-mediated Ythdf2 activation restrains mouse female germline stem cell proliferation via promoting Ets1 mRNA degradation.
Wu Y, Xu B, Peng Y, Lin S, Du W, Liu R, Zhang S, Wu J, Zou K, Zhao X
Clinical epigenetics 2025 May 27;17(1):84
Clinical epigenetics 2025 May 27;17(1):84
PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1.
Hong J, Sui P, Li Y, Xu KY, Lee JH, Wang J, Chen S, Zhang P, Wingate N, Noor A, Yuan Y, Hromas R, Zhou H, Hamamoto K, Su R, Yin CC, Ye F, Quesada AE, Chen J, Huang S, Zhou D, You MJ, Yang FC, Wang J, Xu M
Cell stem cell 2025 Mar 6;32(3):463-478.e6
Cell stem cell 2025 Mar 6;32(3):463-478.e6
Anoikis-related biomarkers PARP1 and SDCBP as diagnostic and therapeutic targets for asthma.
Yang LJ, Song NN, Deng NS, Zhu MJ, Li QQ, Huang SS, Shi X, Hu ZH, Nie HX
Scientific reports 2025 Jul 9;15(1):24779
Scientific reports 2025 Jul 9;15(1):24779
HDAC8 Enhances the Function of HIF-2α by Deacetylating ETS1 to Decrease the Sensitivity of TKIs in ccRCC.
Qian K, Li W, Ren S, Peng W, Qing B, Liu X, Wei X, Zhu L, Wang Y, Jin X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2401142
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2401142
Disruption of blood-brain barrier and endothelial-to-mesenchymal transition are attenuated by Astragalus polysaccharides mediated through upregulation of ETS1 expression in experimental autoimmune encephalomyelitis.
Lu Q, Ma J, Zhao Y, Ding G, Wang Y, Qiao X, Cheng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117521
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117521
Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.
Yang M, Chen Y, Huang X, Shen F, Meng Y
Experimental cell research 2024 Feb 15;435(2):113945
Experimental cell research 2024 Feb 15;435(2):113945
Cellular senescence-Related genes define the immune microenvironment and molecular characteristics in severe asthma patients.
Lin Q, Zheng Z, Ni H, Xu Y, Nie H
Gene 2024 Aug 15;919:148502
Gene 2024 Aug 15;919:148502
METTL14 promotes neuroblastoma formation by inhibiting YWHAH via an m6A-YTHDF1-dependent mechanism.
Wang J, Yin H, Li G, Wu D, Xu Y, Chen Y, Wang X, Xing Y, Zhang T, Fei D, Yang P, Fang F, Tao Y, Li X, Yu J, Yang Y, Li Z, Shi L, Zhang Z, Pan J
Cell death discovery 2024 Apr 22;10(1):186
Cell death discovery 2024 Apr 22;10(1):186
Inhibition of Foxp3 expression in the placenta of mice infected intraperitoneally by toxoplasma gondii tachyzoites: insights into the PPARγ/miR-7b-5p/Sp1 signaling pathway.
Zhong Y, Qin C, Wang Q, Ding M, Qiu C, Xu Y, Chen J
Parasites & vectors 2024 Apr 17;17(1):189
Parasites & vectors 2024 Apr 17;17(1):189
Mutation of the ETS1 3'UTR interacts with miR-216a-3p to regulate granulosa cell apoptosis in sheep.
Yang F, Liu Y, Wang P, Wang X, Chu M, Wang P
Theriogenology 2023 Oct 15;210:133-142
Theriogenology 2023 Oct 15;210:133-142
HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
Ma H, Qi G, Han F, Gai P, Peng J, Kong B
Cell communication and signaling : CCS 2023 Jun 16;21(1):144
Cell communication and signaling : CCS 2023 Jun 16;21(1):144
ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.
Yang M, Chen Y, Huang X, Shen F, Meng Y
Lung 2023 Aug;201(4):425-441
Lung 2023 Aug;201(4):425-441
The RNF26/CBX7 axis modulates the TNF pathway to promote cell proliferation and regulate sensitivity to TKIs in ccRCC.
Liu W, Wang H, Jian C, Li W, Ye K, Ren J, Zhu L, Wang Y, Jin X, Yi L
International journal of biological sciences 2022;18(5):2132-2145
International journal of biological sciences 2022;18(5):2132-2145
The histone demthylase KDM3A protects the myocardium from ischemia/reperfusion injury via promotion of ETS1 expression.
Guo X, Zhang BF, Zhang J, Liu G, Hu Q, Chen J
Communications biology 2022 Mar 25;5(1):270
Communications biology 2022 Mar 25;5(1):270
rSjP40 Inhibited the Activity of Collagen Type I Promoter via Ets-1 in HSCs.
Li J, Zhang J, Zhang B, Chen L, Chen G, Zhu D, Chen J, Duan L, Duan Y
Frontiers in cell and developmental biology 2021;9:765616
Frontiers in cell and developmental biology 2021;9:765616
HIV reprograms host m(6)Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1.
Zhang Q, Kang Y, Wang S, Gonzalez GM, Li W, Hui H, Wang Y, Rana TM
Nature communications 2021 Sep 20;12(1):5543
Nature communications 2021 Sep 20;12(1):5543
p120 inhibits LPS/TNFα-induced endothelial Ang2 synthesis and release in an NF-κB independent fashion.
Li R, Liu Y, Li L, Zhang R, Tang Y
Cytokine 2019 Nov;123:154786
Cytokine 2019 Nov;123:154786
DOT1L promotes angiogenesis through cooperative regulation of VEGFR2 with ETS-1.
Duan Y, Wu X, Zhao Q, Gao J, Huo D, Liu X, Ye Z, Dong X, Fu Z, Shang Y, Xuan C
Oncotarget 2016 Oct 25;7(43):69674-69687
Oncotarget 2016 Oct 25;7(43):69674-69687
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The ETS1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ETS1. This antibody recognizes human, mouse, rat antigen. The ETS1 antibody has been validated for the following applications: ELISA, WB analysis.