BS4316

antibody from Bioworld Technology, Inc
Targeting: ETS1 ETS-1, EWSR2, FLJ10768
Provider product page for BS4316
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS4316 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Ets 1 (phospho T38) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human ETS1 around the phosphorylation site of Threonine 38.
Description
Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1ÿ3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element. Evidence indicates that the DNA binding activity by Ets-1 is regulated at the level of phosphorylation.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ETS1 protein structure - BS4316 shown in red.