ABIN359673
antibody from antibodies-online
Targeting: CDKN1A
CAP20, CDKN1, CIP1, P21, p21CIP1, p21Cip1/Waf1, SDI1, WAF1
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN359673 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The cyclin-dependent kinase inhibitor p21CIP/WAF is a positive regulator of insulin-like growth factor I-induced cell proliferation in MCF-7 human breast cancer cells.
Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter.
CDX2, a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene.
The association of cyclin A and cyclin kinase inhibitor p21 in response to gamma-irradiation requires the CDK2 binding region, but not the Cy motif.
Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners.
Dupont J, Karas M, LeRoith D
The Journal of biological chemistry 2003 Sep 26;278(39):37256-64
The Journal of biological chemistry 2003 Sep 26;278(39):37256-64
Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter.
Di Padova M, Bruno T, De Nicola F, Iezzi S, D'Angelo C, Gallo R, Nicosia D, Corbi N, Biroccio A, Floridi A, Passananti C, Fanciulli M
The Journal of biological chemistry 2003 Sep 19;278(38):36496-504
The Journal of biological chemistry 2003 Sep 19;278(38):36496-504
CDX2, a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene.
Bai YQ, Miyake S, Iwai T, Yuasa Y
Oncogene 2003 Sep 11;22(39):7942-9
Oncogene 2003 Sep 11;22(39):7942-9
The association of cyclin A and cyclin kinase inhibitor p21 in response to gamma-irradiation requires the CDK2 binding region, but not the Cy motif.
Fukuchi K, Nakamura K, Ichimura S, Tatsumi K, Gomi K
Biochimica et biophysica acta 2003 Oct 21;1642(3):163-71
Biochimica et biophysica acta 2003 Oct 21;1642(3):163-71
Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners.
Frouin I, Maga G, Denegri M, Riva F, Savio M, Spadari S, Prosperi E, Scovassi AI
The Journal of biological chemistry 2003 Oct 10;278(41):39265-8
The Journal of biological chemistry 2003 Oct 10;278(41):39265-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC