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LearnMA5-13461
antibody from Invitrogen Antibodies
Targeting: CDKN1A
CAP20, CDKN1, CIP1, P21, p21CIP1, p21Cip1/Waf1, SDI1, WAF1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- MA5-13461 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- p21 Monoclonal Antibody (HJ21 (WA-1))
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- MA5-13461 targets p21WAF1 in IF and WB applications and shows reactivity with Human and Rat samples.
- Antibody clone number
- HJ21 (WA-1)
- Concentration
- 0.2 mg/mL
Submitted references Inhibition of NEDD8-activating enzyme induces rereplication and apoptosis in human tumor cells consistent with deregulating CDT1 turnover.
NEDD8-targeting drug MLN4924 elicits DNA rereplication by stabilizing Cdt1 in S phase, triggering checkpoint activation, apoptosis, and senescence in cancer cells.
Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11.
Cell proliferation inhibition and antitumor activity of novel alkyl series of diorganotin(IV) compounds.
Cyclin-dependent kinase inhibitors and basement membrane interact to regulate breast epithelial cell differentiation and acinar morphogenesis.
Involvement of apoptotic cell death and cell cycle perturbation in retinoic acid-induced cleft palate in mice.
Influence of endogenous glutathione level on X-ray induced cell cycle delay in human lymphocytes.
Chk1 is essential for tumor cell viability following activation of the replication checkpoint.
Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation.
Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells.
Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin).
Milhollen MA, Narayanan U, Soucy TA, Veiby PO, Smith PG, Amidon B
Cancer research 2011 Apr 15;71(8):3042-51
Cancer research 2011 Apr 15;71(8):3042-51
NEDD8-targeting drug MLN4924 elicits DNA rereplication by stabilizing Cdt1 in S phase, triggering checkpoint activation, apoptosis, and senescence in cancer cells.
Lin JJ, Milhollen MA, Smith PG, Narayanan U, Dutta A
Cancer research 2010 Dec 15;70(24):10310-20
Cancer research 2010 Dec 15;70(24):10310-20
Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11.
Kawauchi S, Kim J, Santos R, Wu HH, Lander AD, Calof AL
Development (Cambridge, England) 2009 May;136(9):1453-64
Development (Cambridge, England) 2009 May;136(9):1453-64
Cell proliferation inhibition and antitumor activity of novel alkyl series of diorganotin(IV) compounds.
Koch B, Baul TS, Chatterjee A
Journal of applied toxicology : JAT 2008 May;28(4):430-8
Journal of applied toxicology : JAT 2008 May;28(4):430-8
Cyclin-dependent kinase inhibitors and basement membrane interact to regulate breast epithelial cell differentiation and acinar morphogenesis.
Coppock HA, Gilham DE, Howell A, Clarke RB
Cell proliferation 2007 Oct;40(5):721-40
Cell proliferation 2007 Oct;40(5):721-40
Involvement of apoptotic cell death and cell cycle perturbation in retinoic acid-induced cleft palate in mice.
Okano J, Suzuki S, Shiota K
Toxicology and applied pharmacology 2007 May 15;221(1):42-56
Toxicology and applied pharmacology 2007 May 15;221(1):42-56
Influence of endogenous glutathione level on X-ray induced cell cycle delay in human lymphocytes.
Ray S, Chatterjee A
Cell proliferation 2006 Feb;39(1):37-47
Cell proliferation 2006 Feb;39(1):37-47
Chk1 is essential for tumor cell viability following activation of the replication checkpoint.
Cho SH, Toouli CD, Fujii GH, Crain C, Parry D
Cell cycle (Georgetown, Tex.) 2005 Jan;4(1):131-9
Cell cycle (Georgetown, Tex.) 2005 Jan;4(1):131-9
Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation.
White J, Stead E, Faast R, Conn S, Cartwright P, Dalton S
Molecular biology of the cell 2005 Apr;16(4):2018-27
Molecular biology of the cell 2005 Apr;16(4):2018-27
Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells.
Perego P, Gatti L, Righetti SC, Beretta GL, Carenini N, Corna E, Dal Bo L, Tinelli S, Colangelo D, Leone R, Apostoli P, Lombardi L, Beggiolin G, Piazzoni L, Zunino F
International journal of cancer 2003 Jul 10;105(5):617-24
International journal of cancer 2003 Jul 10;105(5):617-24
Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin).
Lu Y, Zi X, Zhao Y, Mascarenhas D, Pollak M
Journal of the National Cancer Institute 2001 Dec 19;93(24):1852-7
Journal of the National Cancer Institute 2001 Dec 19;93(24):1852-7
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Supportive validation
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot of p21WAF1 using p21WAF1 Monoclonal Antibody (MA5-13461) on PC12 Cells.
