Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN1881730 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Retinoblastoma 1 (RB1) (Ser608), (AA 586-615) antibody
- Antibody type
- Polyclonal
- Antigen
- This RB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-615 amino acids from human RB1.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Ser608,AA 586-615
- Antibody clone number
- RB7977
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references Direct binding of apoptosis signal-regulating kinase 1 to retinoblastoma protein: novel links between apoptotic signaling and cell cycle machinery.
ORF73 of herpesvirus saimiri, a viral homolog of Kaposi's sarcoma-associated herpesvirus, modulates the two cellular tumor suppressor proteins p53 and pRb.
Aberrant expression of pRb and p16(INK4), alone or in combination, indicates poor outcome after resection in patients with colorectal carcinoma.
Dasgupta P, Betts V, Rastogi S, Joshi B, Morris M, Brennan B, Ordonez-Ercan D, Chellappan S
The Journal of biological chemistry 2004 Sep 10;279(37):38762-9
The Journal of biological chemistry 2004 Sep 10;279(37):38762-9
ORF73 of herpesvirus saimiri, a viral homolog of Kaposi's sarcoma-associated herpesvirus, modulates the two cellular tumor suppressor proteins p53 and pRb.
Borah S, Verma SC, Robertson ES
Journal of virology 2004 Oct;78(19):10336-47
Journal of virology 2004 Oct;78(19):10336-47
Aberrant expression of pRb and p16(INK4), alone or in combination, indicates poor outcome after resection in patients with colorectal carcinoma.
Cui X, Shirai Y, Wakai T, Yokoyama N, Hirano S, Hatakeyama K
Human pathology 2004 Oct;35(10):1189-95
Human pathology 2004 Oct;35(10):1189-95
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Rb Antibody (S608) (ABIN1881730) western blot analysis in Daudi,Raji cell line lysates (35 μg/lane). This demonstrates the Rb antibody detected the Rb protein (arrow).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Rb Antibody (S608) (ABIN1881730) western blot analysis in Daudi,Raji cell line lysates (35 μg/lane). This demonstrates the Rb antibody detected the Rb protein (arrow).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Rb Antibody (S608) (ABIN1881730) western blot analysis in Daudi,Raji cell line lysates (35 μg/lane). This demonstrates the Rb antibody detected the Rb protein (arrow).