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- References [22]
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- Product number
- 66085-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66085-1-Ig, RRID:AB_11232033
- Product name
- HDAC1 antibody
- Antibody type
- Monoclonal
- Description
- HDAC1 antibody (Cat. #66085-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4C4G7
- Vial size
- 20ul, 150ul
Submitted references Yes-associated protein induces age-dependent inflammatory signaling in the pulmonary endothelium.
The noncanonical function of liver-type phosphofructokinase potentiates the efficacy of HDAC inhibitors in cancer.
Yes-associated Protein Induces Age-dependent Inflammatory Signaling in the Pulmonary Endothelium.
A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine.
Exosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity.
Anaerobic metabolism promotes breast cancer survival via Histone-3 Lysine-18 lactylation mediating PPARD axis.
Potential mechanisms for chorioamniotic membrane rupture after subchorionic hematoma.
YTHDF2 upregulation and subcellular localization dictate CD8 T cell polyfunctionality in anti-tumor immunity.
Repressing iron overload ameliorates central post-stroke pain via the Hdac2-Kv1.2 axis in a rat model of hemorrhagic stroke.
VPA improves ferroptosis in tubular epithelial cells after cisplatin-induced acute kidney injury.
Anti-Colorectal Cancer Activity of Solasonin from Solanum nigrum L. via Histone Deacetylases-Mediated p53 Acetylation Pathway.
Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.
HDAC1 suppresses radiotherapy sensitivity in cervical cancer via regulating HIF-1α/VEGF signaling pathway.
10-Hydroxydec-2-Enoic Acid Reduces Hydroxyl Free Radical-Induced Damage to Vascular Smooth Muscle Cells by Rescuing Protein and Energy Metabolism.
Fetal macrophages assist in the repair of ruptured amnion through the induction of epithelial-mesenchymal transition.
LncRNA NORAD Promotes Vascular Endothelial Cell Injury and Atherosclerosis Through Suppressing VEGF Gene Transcription via Enhancing H3K9 Deacetylation by Recruiting HDAC6.
Physalin B attenuates liver fibrosis via suppressing LAP2α-HDAC1-mediated deacetylation of the transcription factor GLI1 and hepatic stellate cell activation.
CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis.
Catalytic-independent neuroprotection by SIRT1 is mediated through interaction with HDAC1.
Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner.
ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin.
The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer.
Emin MT, Dubuisson AM, Sujin Kumar P, Knutsen C, Alvira CM, Hough RF
American journal of physiology. Lung cellular and molecular physiology 2025 Sep 1;329(3):L315-L322
American journal of physiology. Lung cellular and molecular physiology 2025 Sep 1;329(3):L315-L322
The noncanonical function of liver-type phosphofructokinase potentiates the efficacy of HDAC inhibitors in cancer.
Shang T, Jiang T, Tan J, Jiang H, Xu M, Pan Y, Lin Y, Cui X, Tian C, Feng H, Chen Y, Pei M, Geng X, Cheng S, Tan Y, Wang H, Dong L
Signal transduction and targeted therapy 2025 Oct 14;10(1):341
Signal transduction and targeted therapy 2025 Oct 14;10(1):341
Yes-associated Protein Induces Age-dependent Inflammatory Signaling in the Pulmonary Endothelium.
Emin MT, Dubuisson AM, Kumar PS, Knutsen C, Alvira CM, Hough RF
bioRxiv : the preprint server for biology 2025 May 16;
bioRxiv : the preprint server for biology 2025 May 16;
A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine.
Zhang P, Zhang Z, Wang Y, Du W, Song X, Lai W, Wang H, Zhu B, Xiong J
EMBO reports 2025 Mar;26(6):1528-1565
EMBO reports 2025 Mar;26(6):1528-1565
Exosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity.
Can C, Yang X, Jia H, Wu H, Guo X, Wei Y, Jia Z, Liu W, Zhang A, He N, Zhang H, Ma D
Molecular cancer 2025 Jan 6;24(1):4
Molecular cancer 2025 Jan 6;24(1):4
Anaerobic metabolism promotes breast cancer survival via Histone-3 Lysine-18 lactylation mediating PPARD axis.
Xu Y, Meng W, Dai Y, Xu L, Ding N, Zhang J, Zhuang X
Cell death discovery 2025 Feb 8;11(1):54
Cell death discovery 2025 Feb 8;11(1):54
Potential mechanisms for chorioamniotic membrane rupture after subchorionic hematoma.
Yasuda E, Kawamura Y, Ueda Y, Takakura M, Matsuzaka Y, Matsuzaka S, Inohaya A, Chigusa Y, Mandai M, Mogami H
American journal of obstetrics and gynecology 2025 Aug;233(2):125.e1-125.e18
American journal of obstetrics and gynecology 2025 Aug;233(2):125.e1-125.e18
YTHDF2 upregulation and subcellular localization dictate CD8 T cell polyfunctionality in anti-tumor immunity.
Zhang H, Luo X, Yang W, Wu Z, Zhao Z, Pei X, Zhang X, Chen C, Lei JH, Shi Q, Zhao Q, Chen Y, Wu W, Zeng Z, Ju HQ, Qiu M, Liu J, Shen B, Chen M, Chen J, Deng CX, Xu RH, Hou J
Nature communications 2024 Nov 5;15(1):9559
Nature communications 2024 Nov 5;15(1):9559
Repressing iron overload ameliorates central post-stroke pain via the Hdac2-Kv1.2 axis in a rat model of hemorrhagic stroke.
Fang H, Li M, Yang J, Ma S, Zhang L, Yang H, Tang Q, Cao J, Yang W
Neural regeneration research 2024 Dec 1;19(12):2708-2722
Neural regeneration research 2024 Dec 1;19(12):2708-2722
VPA improves ferroptosis in tubular epithelial cells after cisplatin-induced acute kidney injury.
Li Y, Li K, Zhao W, Wang H, Xue X, Chen X, Li W, Xu P, Wang K, Liu P, Tian X, Fu R
Frontiers in pharmacology 2023;14:1147772
Frontiers in pharmacology 2023;14:1147772
Anti-Colorectal Cancer Activity of Solasonin from Solanum nigrum L. via Histone Deacetylases-Mediated p53 Acetylation Pathway.
Lan X, Lu M, Fang X, Cao Y, Sun M, Shan M, Gao W, Wang Y, Yu W, Luo H
Molecules (Basel, Switzerland) 2023 Sep 15;28(18)
Molecules (Basel, Switzerland) 2023 Sep 15;28(18)
Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.
Dai Y, Wei T, Huang Y, Bei Y, Lin H, Shen Z, Yu L, Yang M, Xu H, He W, Lin Z, Dai H
Cellular and molecular life sciences : CMLS 2023 Sep 10;80(10):289
Cellular and molecular life sciences : CMLS 2023 Sep 10;80(10):289
HDAC1 suppresses radiotherapy sensitivity in cervical cancer via regulating HIF-1α/VEGF signaling pathway.
Liu L, Gu K, Hua D
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Nov 15;69(11):132-140
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Nov 15;69(11):132-140
10-Hydroxydec-2-Enoic Acid Reduces Hydroxyl Free Radical-Induced Damage to Vascular Smooth Muscle Cells by Rescuing Protein and Energy Metabolism.
Fan P, Sha F, Ma C, Wei Q, Zhou Y, Shi J, Fu J, Zhang L, Han B, Li J
Frontiers in nutrition 2022;9:873892
Frontiers in nutrition 2022;9:873892
Fetal macrophages assist in the repair of ruptured amnion through the induction of epithelial-mesenchymal transition.
Kawamura Y, Mogami H, Yasuda E, Takakura M, Matsuzaka Y, Ueda Y, Inohaya A, Kawasaki K, Chigusa Y, Mandai M, Kondoh E
Science signaling 2022 Sep 13;15(751):eabi5453
Science signaling 2022 Sep 13;15(751):eabi5453
LncRNA NORAD Promotes Vascular Endothelial Cell Injury and Atherosclerosis Through Suppressing VEGF Gene Transcription via Enhancing H3K9 Deacetylation by Recruiting HDAC6.
Kai H, Wu Q, Yin R, Tang X, Shi H, Wang T, Zhang M, Pan C
Frontiers in cell and developmental biology 2021;9:701628
Frontiers in cell and developmental biology 2021;9:701628
Physalin B attenuates liver fibrosis via suppressing LAP2α-HDAC1-mediated deacetylation of the transcription factor GLI1 and hepatic stellate cell activation.
Zhu X, Ye S, Yu D, Zhang Y, Li J, Zhang M, Leng Y, Yang T, Luo J, Chen X, Zhang H, Kong L
British journal of pharmacology 2021 Sep;178(17):3428-3447
British journal of pharmacology 2021 Sep;178(17):3428-3447
CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis.
Zhang X, Lu J, Zhang Q, Luo Q, Liu B
Biological research 2021 Mar 23;54(1):11
Biological research 2021 Mar 23;54(1):11
Catalytic-independent neuroprotection by SIRT1 is mediated through interaction with HDAC1.
Pfister JA, Ma C, D'Mello SR
PloS one 2019;14(4):e0215208
PloS one 2019;14(4):e0215208
Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner.
Datta M, Staszewski O, Raschi E, Frosch M, Hagemeyer N, Tay TL, Blank T, Kreutzfeldt M, Merkler D, Ziegler-Waldkirch S, Matthias P, Meyer-Luehmann M, Prinz M
Immunity 2018 Mar 20;48(3):514-529.e6
Immunity 2018 Mar 20;48(3):514-529.e6
ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin.
Li L, Liu X, He L, Yang J, Pei F, Li W, Liu S, Chen Z, Xie G, Xu B, Ting X, Zhang Z, Jin T, Liu X, Zhang W, Yuan S, Yang Z, Wu C, Zhang Y, Yang X, Yi X, Liang J, Shang Y, Sun L
Nature communications 2017 Sep 25;8(1):691
Nature communications 2017 Sep 25;8(1):691
The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer.
Li W, Zhang Z, Liu X, Cheng X, Zhang Y, Han X, Zhang Y, Liu S, Yang J, Xu B, He L, Sun L, Liang J, Shang Y
The Journal of clinical investigation 2017 Sep 1;127(9):3421-3440
The Journal of clinical investigation 2017 Sep 1;127(9):3421-3440
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HDAC1 antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human HDAC1. This antibody recognizes human antigen. The HDAC1 antibody has been validated for the following applications: ELISA, WB analysis.
