Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 22765-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SPRY4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SPRY4 antibody (Cat. #22765-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Coupling HDAC4 with transcriptional factor MEF2D abrogates SPRY4-mediated suppression of ERK activation and elicits hepatocellular carcinoma drug resistance.
SPRY4 regulates trophoblast proliferation and apoptosis via regulating IFN-γ-induced STAT1 expression and activation in recurrent miscarriage.
SPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells.
AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cells.
Ma Q, Xu Q, Zhao J, Zhang W, Wang Q, Fang J, Lu Z, Liu J, Ma L
Cancer letters 2021 Nov 1;520:243-254
Cancer letters 2021 Nov 1;520:243-254
SPRY4 regulates trophoblast proliferation and apoptosis via regulating IFN-γ-induced STAT1 expression and activation in recurrent miscarriage.
Qin S, Zhang Y, Zhang J, Tian F, Sun L, He X, Ma X, Zhang J, Liu XR, Zeng W, Lin Y
American journal of reproductive immunology (New York, N.Y. : 1989) 2020 Jun;83(6):e13234
American journal of reproductive immunology (New York, N.Y. : 1989) 2020 Jun;83(6):e13234
SPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells.
Li J, Li N, Chen Y, Hui S, Fan J, Ye B, Fan Z, Zhang J, Zhao RC, Zhuang Q
Cell death & disease 2019 Oct 23;10(11):805
Cell death & disease 2019 Oct 23;10(11):805
AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cells.
Taniguchi H, Yamada T, Wang R, Tanimura K, Adachi Y, Nishiyama A, Tanimoto A, Takeuchi S, Araujo LH, Boroni M, Yoshimura A, Shiotsu S, Matsumoto I, Watanabe S, Kikuchi T, Miura S, Tanaka H, Kitazaki T, Yamaguchi H, Mukae H, Uchino J, Uehara H, Takayama K, Yano S
Nature communications 2019 Jan 16;10(1):259
Nature communications 2019 Jan 16;10(1):259
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 22765-1-AP( SPRY4 Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SPRY4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SPRY4. This antibody recognizes human antigen. The SPRY4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.