ABIN1881744

antibody from antibodies-online

Targeting: RFFL CARP-2, CARP2, fring, rififylin, RNF189, RNF34L

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN1881744

Provider

antibodies-online

Product name

anti-Ring Finger and FYVE-Like Domain Containing 1 (RFFL) (C-Term), (AA 265-294) antibody

Antibody type

Polyclonal

Antigen

This RFFL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the C-terminal region of human RFFL.

Description

This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Reactivity

Human

Host

Rabbit

Epitope

C-Term,AA 265-294

Antibody clone number

RB40306

Vial size

400 μL

Concentration

0.5 mg/mL

References

Submitted references

Common variants at ten loci influence QT interval duration in the QTGEN Study.

Newton-Cheh C, Eijgelsheim M, Rice KM, de Bakker PI, Yin X, Estrada K, Bis JC, Marciante K, Rivadeneira F, Noseworthy PA, Sotoodehnia N, Smith NL, Rotter JI, Kors JA, Witteman JC, Hofman A, Heckbert SR, O'Donnell CJ, Uitterlinden AG, Psaty BM, Lumley T, Larson MG, Stricker BH
Nature genetics 2009 Apr;41(4):399-406

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CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation.

Liao W, Xiao Q, Tchikov V, Fujita K, Yang W, Wincovitch S, Garfield S, Conze D, El-Deiry WS, Schütze S, Srinivasula SM
Current biology : CB 2008 May 6;18(9):641-9

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

RFFL Antibody (C-term) (ABIN1881744) western blot analysis in A2058 cell line lysates (35 μg/lane). This demonstrates the RFFL antibody detected the RFFL protein (arrow).