ABIN401251

antibody from antibodies-online

Targeting: SFRP1 FRP, FRP-1, SARP2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN401251

Provider

antibodies-online

Product name

anti-Secreted Frizzled-Related Protein 1 (SFRP1) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide corresponding to a 12 amino acid region of Human Sfrp1 protein

Description

Immunoaffinity Chromatography

Reactivity

Human, Mouse, Rat, Bovine

Host

Rabbit

Isotype

IgG

Vial size

0.1 mg

Concentration

0.56 mg/mL (by UV absorbance at 280 nm)

Storage

Store undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Evaluation of SFRP1 as a candidate for human retinal dystrophies.

Garcia-Hoyos M, Cantalapiedra D, Arroyo C, Esteve P, Rodríguez J, Riveiro R, Trujillo MJ, Ramos C, Bovolenta P, Ayuso C
Molecular vision 2004 Jun 28;10:426-31

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Secreted frizzled-related protein 1 (SFRP1) protects fibroblasts from ceramide-induced apoptosis.

Han X, Amar S
The Journal of biological chemistry 2004 Jan 23;279(4):2832-40

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Human secreted frizzled-related protein is down-regulated and induces apoptosis in human cervical cancer.

Ko J, Ryu KS, Lee YH, Na DS, Kim YS, Oh YM, Kim IS, Kim JW
Experimental cell research 2002 Nov 1;280(2):280-7

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Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules.

Chong JM, Uren A, Rubin JS, Speicher DW
The Journal of biological chemistry 2002 Feb 15;277(7):5134-44

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Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling.

Uren A, Reichsman F, Anest V, Taylor WG, Muraiso K, Bottaro DP, Cumberledge S, Rubin JS
The Journal of biological chemistry 2000 Feb 11;275(6):4374-82

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Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action.

Finch PW, He X, Kelley MJ, Uren A, Schaudies RP, Popescu NC, Rudikoff S, Aaronson SA, Varmus HE, Rubin JS
Proceedings of the National Academy of Sciences of the United States of America 1997 Jun 24;94(13):6770-5

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SARPs: a family of secreted apoptosis-related proteins.

Melkonyan HS, Chang WC, Shapiro JP, Mahadevappa M, Fitzpatrick PA, Kiefer MC, Tomei LD, Umansky SR
Proceedings of the National Academy of Sciences of the United States of America 1997 Dec 9;94(25):13636-41

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A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.

Rattner A, Hsieh JC, Smallwood PM, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J
Proceedings of the National Academy of Sciences of the United States of America 1997 Apr 1;94(7):2859-63