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- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 66121-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- Alpha Galactosidase A antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated Alpha Galactosidase A antibody (Cat. #66121-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2B2C5
- Vial size
- 20ul, 150ul
Submitted references Signal Peptide Engineering and Codon Optimization to Enhance α-Gal A Activity for rAAV Gene Therapy of Fabry Disease.
The mTORC2 subunit RICTOR drives breast cancer progression by promoting ganglioside biosynthesis through transcriptional and epigenetic mechanisms.
A Common PD-Risk GBA1 Variant Disrupts LIMP2 Interaction, Impairs Glucocerebrosidase Function, and Drives Lysosomal and Mitochondrial Dysfunction.
Comparative Evaluation of AAV8 and AAV9 Gene Therapy in Fabry Knockout (Gla(-/y)) and Symptomatic (G3S(Tg/+)Gla(-/y)) Murine Models.
Antigen-display exosomes provide adjuvant-free protection against SARS-CoV-2 disease at nanogram levels of spike protein.
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.
He S, Yang L, Wan K, Zheng Z, Leng M, Gan C, Liu Y, Xiao L, Ye J, Chen Z, Zhou J, Valencia CA, Abuammah A, Chow HY, Dong B, Chen Y
Journal of inherited metabolic disease 2026 Mar;49(2):e70168
Journal of inherited metabolic disease 2026 Mar;49(2):e70168
The mTORC2 subunit RICTOR drives breast cancer progression by promoting ganglioside biosynthesis through transcriptional and epigenetic mechanisms.
Ansari MN, Jha SK, Khan A, Rajput K, Pandey N, Jain D, Tripathi R, Medatwal N, Sharma P, Datta S, Kar A, Pani T, Ali SA, Cholke K, Rana K, Snijesh VP, Mukherjee G, Deo SVS, Basak S, Mishra A, Prabhu JS, Mukhopadhyay A, Bajaj A, Dasgupta U
PLoS biology 2025 Sep;23(9):e3003362
PLoS biology 2025 Sep;23(9):e3003362
A Common PD-Risk GBA1 Variant Disrupts LIMP2 Interaction, Impairs Glucocerebrosidase Function, and Drives Lysosomal and Mitochondrial Dysfunction.
Davis OB, Kung JE, Davis SS, Ghosh R, Andrews SV, Gould NS, Kluss JH, Thomsen E, Agam M, Coan JP, Maloney MT, Nguyen AH, Nguyen HN, Propson NE, Lozano EI, Yuan T, Xa K, Sperberg RAP, Jain S, Lawrence R, Ullman JC, Balasundar S, Benton HP, Petkovic M, Qerqez AN, Wang X, Zhu S, Di Paolo G, Kariolis MS, Mahon CS, Arguello A, Vocadlo DJ, Cookson MR, Suh JH, Rougé L, Henry AG
bioRxiv : the preprint server for biology 2025 Sep 2;
bioRxiv : the preprint server for biology 2025 Sep 2;
Comparative Evaluation of AAV8 and AAV9 Gene Therapy in Fabry Knockout (Gla(-/y)) and Symptomatic (G3S(Tg/+)Gla(-/y)) Murine Models.
Chang FP, Lee YT, Liu PH, Chen PS, Chen YR, Niu DM
Genes 2025 Jun 29;16(7)
Genes 2025 Jun 29;16(7)
Antigen-display exosomes provide adjuvant-free protection against SARS-CoV-2 disease at nanogram levels of spike protein.
Guo C, Sachithanandham J, Zhong W, Craney M, Villano J, Pekosz A, Gould SJ
bioRxiv : the preprint server for biology 2024 Jan 5;
bioRxiv : the preprint server for biology 2024 Jan 5;
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.
Boland S, Swarup S, Ambaw YA, Malia PC, Richards RC, Fischer AW, Singh S, Aggarwal G, Spina S, Nana AL, Grinberg LT, Seeley WW, Surma MA, Klose C, Paulo JA, Nguyen AD, Harper JW, Walther TC, Farese RV Jr
Nature communications 2022 Oct 7;13(1):5924
Nature communications 2022 Oct 7;13(1):5924
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 66121-1-Ig(GLA antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Alpha galactosidase A antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human Alpha galactosidase A. This antibody recognizes human antigen. The Alpha galactosidase A antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
