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- References [24]
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- Product number
- 13019-3-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13019-3-AP, RRID:AB_2199414
- Product name
- TFAP2A,AP-2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TFAP2A,AP-2 antibody (Cat. #13019-3-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references DEAF1 confers resistance to adriamycin-induced apoptosis and pyroptosis in multiple myeloma.
TFAP2A regulates SGPP2 transcription to promote lipid accumulation and activate the Wnt/β-catenin signaling pathway to promote malignant progression in lung adenocarcinoma.
The role of autophagy in intervertebral disc degeneration and the regulation mechanism of AP-2α on autophagy.
Silencing of lncRNA TFAP2A-AS1 attenuates the development of acute coronary syndrome by inhibiting TFAP2A expression.
Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation.
Mapping the Subtype-Specific PARP1 ADP-ribosylated Proteome in Breast Cancer Cells.
HNRNPC promotes progression of non-small cell lung cancer by maintaining TFAP2A mRNA stability.
Erzhi pill promotes norepinephrine synthesis in locus coeruleus through ERβ-TFAP2A-TH plays a neuroprotective role.
Super-enhancers orchestrate transcriptional dysregulation and metabolic reprogramming in uveal melanoma.
TFAP2A upregulates FAM83A to suppress ferroptosis and diminish cisplatin sensitivity in non-small cell lung cancer.
FOXP1 is a Transcription Factor for the Alzheimer's Disease Risk Gene SORL1.
CircRNA hsa_ circ_0009022 inhibits colorectal cancer progression by sponging miR-576-5p and complexing with FMRP.
Overcoming Cancer Persister Cells by Stabilizing the ATF4 Promoter G-quadruplex.
Dahuang Huanglian Xiexin Decoction ameliorates obesity via modulating adipocyte differentiation and lipid degradation through inhibiting endoplasmic reticulum stress.
Transcriptional and post-transcriptional regulation of CARMN and its anti-tumor function in cervical cancer through autophagic flux blockade and MAPK cascade inhibition.
Polymorphism rs2327430 in TCF21 predicts the risk and prognosis of gastric cancer by affecting the binding between TFAP2A and TCF21.
miR-1293 suppresses osteosarcoma progression by modulating drug sensitivity in response to cisplatin treatment.
Macroscopic inhibition of DNA damage repair pathways by targeting AP-2α with LEI110 eradicates hepatocellular carcinoma.
Alarmin S100A8 imparts chemoresistance of esophageal cancer by reprogramming cancer-associated fibroblasts.
Cajaninstilbene acid ameliorates depression-like behaviors in mice by suppressing TLR4/NF-κB mediated neuroinflammation and promoting autophagy.
The m6A modification-mediated OGDHL exerts a tumor suppressor role in ccRCC by downregulating FASN to inhibit lipid synthesis and ERK signaling.
TFAP2A potentiates lung adenocarcinoma metastasis by a novel miR-16 family/TFAP2A/PSG9/TGF-β signaling pathway.
Regulation of DEK expression by AP-2α and methylation level of DEK promoter in hepatocellular carcinoma.
Hepatitis B virus X protein promotes human hepatoma cell growth via upregulation of transcription factor AP2α and sphingosine kinase 1.
Deng Z, Wei Y, Liu S, Chen L, Wang X, Liu Z, Liu L, Wang Y, Lv X, Sun S, Ni H, Gu C, Yang Y
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Mar;85:101344
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Mar;85:101344
TFAP2A regulates SGPP2 transcription to promote lipid accumulation and activate the Wnt/β-catenin signaling pathway to promote malignant progression in lung adenocarcinoma.
Li Q, Li J, Zhang C, Deng Y, Yang B, Ma L, Liu Y, Wang C, Xu L, Mei J
Journal of translational medicine 2026 Mar 4;24(1)
Journal of translational medicine 2026 Mar 4;24(1)
The role of autophagy in intervertebral disc degeneration and the regulation mechanism of AP-2α on autophagy.
He J, Li W, Chen F, Yin G, Tang L, Fan Q
The international journal of biochemistry & cell biology 2026 Jan;190:106876
The international journal of biochemistry & cell biology 2026 Jan;190:106876
Silencing of lncRNA TFAP2A-AS1 attenuates the development of acute coronary syndrome by inhibiting TFAP2A expression.
Huang S, Guan F, Ye F, Ye B, Han S, Chen H
Biomedical reports 2026 Feb;24(2):20
Biomedical reports 2026 Feb;24(2):20
Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation.
Guo W, Zhang C, Zhou Q, Chen T, Xu X, Zhang J, Yu X, Wu H, Zhang X, Ma L, Qian K, Klionsky DJ, Kang R, Kroemer G, Yu Y, Tang D, Wang J
Developmental cell 2025 Sep 8;60(17):2294-2312.e11
Developmental cell 2025 Sep 8;60(17):2294-2312.e11
Mapping the Subtype-Specific PARP1 ADP-ribosylated Proteome in Breast Cancer Cells.
Koul S, Kwon M, Tapadar P, Dai Y, Nandu T, Huang D, Camacho CV, Kraus WL
bioRxiv : the preprint server for biology 2025 Sep 30;
bioRxiv : the preprint server for biology 2025 Sep 30;
HNRNPC promotes progression of non-small cell lung cancer by maintaining TFAP2A mRNA stability.
Liao M, Li C, Yang R, Li J, Wu K, Zhang J, Zhu Q, Shi Y, Zhang X
Cancer cell international 2025 Mar 8;25(1):85
Cancer cell international 2025 Mar 8;25(1):85
Erzhi pill promotes norepinephrine synthesis in locus coeruleus through ERβ-TFAP2A-TH plays a neuroprotective role.
Xue A, Zhao D, Xu H, Lei X, Li D, Ren Y, Zhou Q, Qiu Q, Cai L, Zhang Y, Zhang N
Journal of ethnopharmacology 2025 Jun 26;350:120015
Journal of ethnopharmacology 2025 Jun 26;350:120015
Super-enhancers orchestrate transcriptional dysregulation and metabolic reprogramming in uveal melanoma.
Pan H, Shao W, Wang H, Ge S, Zhang L, Xu X, Wang Y, Zhuang A
Communications biology 2025 Jun 23;8(1):951
Communications biology 2025 Jun 23;8(1):951
TFAP2A upregulates FAM83A to suppress ferroptosis and diminish cisplatin sensitivity in non-small cell lung cancer.
Sun Q, Qu W, Wang Y, Yang K, Weng Y
Cell division 2025 Jul 11;20(1):19
Cell division 2025 Jul 11;20(1):19
FOXP1 is a Transcription Factor for the Alzheimer's Disease Risk Gene SORL1.
Fu X, Quan S, Liang W, Li Y, Cai H, Ren Z, Xu Y, Wang Z, Jia L
Journal of neurochemistry 2025 Feb;169(2):e70011
Journal of neurochemistry 2025 Feb;169(2):e70011
CircRNA hsa_ circ_0009022 inhibits colorectal cancer progression by sponging miR-576-5p and complexing with FMRP.
Guo J, Wang Y, Yang Y, Feng S, Cai J, Fan S, Wang J, Li N, Qian X, Zhu H
Tissue & cell 2025 Aug;95:102924
Tissue & cell 2025 Aug;95:102924
Overcoming Cancer Persister Cells by Stabilizing the ATF4 Promoter G-quadruplex.
Xiao C, Li Y, Liu Y, Dong R, He X, Lin Q, Zang X, Wang K, Xia Y, Kong L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(35):e2401748
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(35):e2401748
Dahuang Huanglian Xiexin Decoction ameliorates obesity via modulating adipocyte differentiation and lipid degradation through inhibiting endoplasmic reticulum stress.
Hao L, Li M, Gu H, Li J
Prostaglandins & other lipid mediators 2024 Oct;174:106874
Prostaglandins & other lipid mediators 2024 Oct;174:106874
Transcriptional and post-transcriptional regulation of CARMN and its anti-tumor function in cervical cancer through autophagic flux blockade and MAPK cascade inhibition.
Zhang X, Yan W, Jin H, Yu B, Zhang H, Ding B, Chen X, Zhang Y, Xia Q, Meng D, Hu J, Liu H, Nie Y, Liu F, Zheng Y, Lu Y, Wang J, Du M, Wang M, Yu EY, Li X, Wang S
Journal of experimental & clinical cancer research : CR 2024 Nov 19;43(1):305
Journal of experimental & clinical cancer research : CR 2024 Nov 19;43(1):305
Polymorphism rs2327430 in TCF21 predicts the risk and prognosis of gastric cancer by affecting the binding between TFAP2A and TCF21.
Zhou X, Shen K, Cao S, Li P, Xiao J, Dong J, Cheng Q, Hu L, Xu Z, Yang L
Cancer cell international 2024 May 7;24(1):159
Cancer cell international 2024 May 7;24(1):159
miR-1293 suppresses osteosarcoma progression by modulating drug sensitivity in response to cisplatin treatment.
Wang T, Huang J, Chen G, Fu J, Li T, Zou X, Yi H
International immunopharmacology 2024 Mar 30;130:111702
International immunopharmacology 2024 Mar 30;130:111702
Macroscopic inhibition of DNA damage repair pathways by targeting AP-2α with LEI110 eradicates hepatocellular carcinoma.
Wang C, Zhao Z, Zhao Y, Zhao J, Xia L, Xia Q
Communications biology 2024 Mar 19;7(1):342
Communications biology 2024 Mar 19;7(1):342
Alarmin S100A8 imparts chemoresistance of esophageal cancer by reprogramming cancer-associated fibroblasts.
Chen X, Cheng G, Zhu L, Liu T, Yang X, Liu R, Ou Z, Zhang S, Tan W, Lin D, Wu C
Cell reports. Medicine 2024 Jun 18;5(6):101576
Cell reports. Medicine 2024 Jun 18;5(6):101576
Cajaninstilbene acid ameliorates depression-like behaviors in mice by suppressing TLR4/NF-κB mediated neuroinflammation and promoting autophagy.
Tao X, Zhou Y, Wang Z, Wang L, Xia T, Yan M, Chang Q
Behavioural brain research 2024 Aug 5;471:115142
Behavioural brain research 2024 Aug 5;471:115142
The m6A modification-mediated OGDHL exerts a tumor suppressor role in ccRCC by downregulating FASN to inhibit lipid synthesis and ERK signaling.
Shi J, Miao D, Lv Q, Wang K, Wang Q, Liang H, Yang H, Xiong Z, Zhang X
Cell death & disease 2023 Aug 25;14(8):560
Cell death & disease 2023 Aug 25;14(8):560
TFAP2A potentiates lung adenocarcinoma metastasis by a novel miR-16 family/TFAP2A/PSG9/TGF-β signaling pathway.
Xiong Y, Feng Y, Zhao J, Lei J, Qiao T, Zhou Y, Lu Q, Jiang T, Jia L, Han Y
Cell death & disease 2021 Apr 6;12(4):352
Cell death & disease 2021 Apr 6;12(4):352
Regulation of DEK expression by AP-2α and methylation level of DEK promoter in hepatocellular carcinoma.
Qiao MX, Li C, Zhang AQ, Hou LL, Yang J, Hu HG
Oncology reports 2016 Oct;36(4):2382-90
Oncology reports 2016 Oct;36(4):2382-90
Hepatitis B virus X protein promotes human hepatoma cell growth via upregulation of transcription factor AP2α and sphingosine kinase 1.
Lu ZP, Xiao ZL, Yang Z, Li J, Feng GX, Chen FQ, Li YH, Feng JY, Gao YE, Ye LH, Zhang XD
Acta pharmacologica Sinica 2015 Oct;36(10):1228-36
Acta pharmacologica Sinica 2015 Oct;36(10):1228-36
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TFAP2A,AP-2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TFAP2A,AP-2. This antibody recognizes human, mouse, rat antigen. The TFAP2A,AP-2 antibody has been validated for the following applications: ELISA, WB analysis.
