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- Antigen structure
- References [17]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 22474-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- FOXA2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FOXA2 antibody (Cat. #22474-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NatD epigenetically activates FOXA2 expression to promote breast cancer progression by facilitating MMP14 expression.
Fenofibrate Attenuates Renal Tubular Cell Apoptosis by Up-Regulating MCAD in Diabetic Kidney Disease.
FOXA2 and STAT5A regulate oncogenic activity of KIF5B-RET fusion.
METTL14 regulates chromatin bivalent domains in mouse embryonic stem cells.
Dopamine-related oxidative stress and mitochondrial dysfunction in dopaminergic neurons differentiated from deciduous teeth-derived stem cells of children with Down syndrome.
An artificial LAMA2-GelMA hydrogel microenvironment for the development of pancreatic endocrine progenitors.
Forkhead box A2 transcriptionally activates hsa-let-7 g to inhibit hypoxia-induced epithelial-mesenchymal transition by targeting c14orf28 in colorectal cancer.
Epigenetically silenced linc00261 contributes to the metastasis of hepatocellular carcinoma via inducing the deficiency of FOXA2 transcription.
Changes in the hepatic differentiation potential of human mesenchymal stem cells aged in vitro.
Mof acetyltransferase inhibition ameliorates glucose intolerance and islet dysfunction of type 2 diabetes via targeting pancreatic α-cells.
Functional hit 1 (FH1)-based rapid and efficient generation of functional hepatocytes from human mesenchymal stem cells: a novel strategy for hepatic differentiation.
Comparative cytotoxicity studies of halophenolic disinfection byproducts using human extended pluripotent stem cells.
Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer.
Azoramide protects iPSC-derived dopaminergic neurons with PLA2G6 D331Y mutation through restoring ER function and CREB signaling.
EGF suppresses the expression of miR-124a in pancreatic β cell lines via ETS2 activation through the MEK and PI3K signaling pathways.
Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.
Early prediction of the differentiation potential during the formation of human iPSC-derived embryoid bodies.
Xing M, Yao B, Xu J, Lu P, Li Q, Wu D, Chen B, Wei J, Su L, Zhao Q
iScience 2024 Feb 16;27(2):108840
iScience 2024 Feb 16;27(2):108840
Fenofibrate Attenuates Renal Tubular Cell Apoptosis by Up-Regulating MCAD in Diabetic Kidney Disease.
Tang C, Deng X, Qu J, Miao Y, Tian L, Zhang M, Li X, Sun B, Chen L
Drug design, development and therapy 2023;17:1503-1514
Drug design, development and therapy 2023;17:1503-1514
FOXA2 and STAT5A regulate oncogenic activity of KIF5B-RET fusion.
Lee MR, Shin JY, Kim MY, Kim JO, Jung CK, Kang J
American journal of cancer research 2023;13(2):638-653
American journal of cancer research 2023;13(2):638-653
METTL14 regulates chromatin bivalent domains in mouse embryonic stem cells.
Mu M, Li X, Dong L, Wang J, Cai Q, Hu Y, Wang D, Zhao P, Zhang L, Zhang D, Cheng S, Tan L, Wu F, Shi YG, Xu W, Shi Y, Shen H
Cell reports 2023 Jun 27;42(6):112650
Cell reports 2023 Jun 27;42(6):112650
Dopamine-related oxidative stress and mitochondrial dysfunction in dopaminergic neurons differentiated from deciduous teeth-derived stem cells of children with Down syndrome.
Sun X, Kato H, Sato H, Han X, Hirofuji Y, Kato TA, Sakai Y, Ohga S, Fukumoto S, Masuda K
FASEB bioAdvances 2022 Jul;4(7):454-467
FASEB bioAdvances 2022 Jul;4(7):454-467
An artificial LAMA2-GelMA hydrogel microenvironment for the development of pancreatic endocrine progenitors.
Huang Y, Xu Y, Zhu J, Wan J, Xiong Y, Jiang Z, Zhu S, Guo Q, Li Y, Lu Y, Yu B, Guo Y, Wang Z, Yang Y
Biomaterials 2022 Dec;291:121882
Biomaterials 2022 Dec;291:121882
Forkhead box A2 transcriptionally activates hsa-let-7 g to inhibit hypoxia-induced epithelial-mesenchymal transition by targeting c14orf28 in colorectal cancer.
Ouyang C, Fu Q, Xie Y, Xie J
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2022 Aug;23(3):188-194
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2022 Aug;23(3):188-194
Epigenetically silenced linc00261 contributes to the metastasis of hepatocellular carcinoma via inducing the deficiency of FOXA2 transcription.
Chen Z, Xiang L, Hu Z, Ou H, Liu X, Yu L, Chen W, Jiang L, Yu Q, Fang Y, Xu Y, Liu Q, Huang Y, Li X, Yang D
American journal of cancer research 2021;11(1):277-296
American journal of cancer research 2021;11(1):277-296
Changes in the hepatic differentiation potential of human mesenchymal stem cells aged in vitro.
Luo S, Xiao S, Ai Y, Wang B, Wang Y
Annals of translational medicine 2021 Nov;9(21):1628
Annals of translational medicine 2021 Nov;9(21):1628
Mof acetyltransferase inhibition ameliorates glucose intolerance and islet dysfunction of type 2 diabetes via targeting pancreatic α-cells.
Guo X, Cui C, Song J, He Q, Zang N, Hu H, Wang X, Li D, Wang C, Hou X, Li X, Liang K, Yan F, Chen L
Molecular and cellular endocrinology 2021 Nov 1;537:111425
Molecular and cellular endocrinology 2021 Nov 1;537:111425
Functional hit 1 (FH1)-based rapid and efficient generation of functional hepatocytes from human mesenchymal stem cells: a novel strategy for hepatic differentiation.
Luo S, Ai Y, Xiao S, Wang B, Wang Y
Annals of translational medicine 2021 Jul;9(13):1087
Annals of translational medicine 2021 Jul;9(13):1087
Comparative cytotoxicity studies of halophenolic disinfection byproducts using human extended pluripotent stem cells.
Liu Y, Zhu D, Zhao Z, Zhou Q, Pan Y, Shi W, Qiu J, Yang Y
Chemosphere 2021 Jan;263:127899
Chemosphere 2021 Jan;263:127899
Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer.
Teng S, Li YE, Yang M, Qi R, Huang Y, Wang Q, Zhang Y, Chen S, Li S, Lin K, Cao Y, Ji Q, Gu Q, Cheng Y, Chang Z, Guo W, Wang P, Garcia-Bassets I, Lu ZJ, Wang D
Cell research 2020 Jan;30(1):34-49
Cell research 2020 Jan;30(1):34-49
Azoramide protects iPSC-derived dopaminergic neurons with PLA2G6 D331Y mutation through restoring ER function and CREB signaling.
Ke M, Chong CM, Zeng H, Huang M, Huang Z, Zhang K, Cen X, Lu JH, Yao X, Qin D, Su H
Cell death & disease 2020 Feb 18;11(2):130
Cell death & disease 2020 Feb 18;11(2):130
EGF suppresses the expression of miR-124a in pancreatic β cell lines via ETS2 activation through the MEK and PI3K signaling pathways.
Yang L, Zhu Y, Kong D, Gong J, Yu W, Liang Y, Nie Y, Teng CB
International journal of biological sciences 2019;15(12):2561-2575
International journal of biological sciences 2019;15(12):2561-2575
Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.
Chen B, Yu J, Lu L, Dong F, Zhou F, Tao X, Sun E
Oncology letters 2019 May;17(5):4351-4360
Oncology letters 2019 May;17(5):4351-4360
Early prediction of the differentiation potential during the formation of human iPSC-derived embryoid bodies.
Guo NN, Liu LP, Zhang YX, Cai YT, Guo Y, Zheng YW, Li YM
Biochemical and biophysical research communications 2019 Aug 27;516(3):673-679
Biochemical and biophysical research communications 2019 Aug 27;516(3):673-679
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 22474-1-AP( FOXA2 Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-FOXA2 (IP:22474-1-AP, 3ug; Detection:22474-1-AP 1:300) with HepG2 cells lysate 1920ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FOXA2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human FOXA2. This antibody recognizes human antigen. The FOXA2 antibody has been validated for the following applications: ELISA, IP, WB, IHC analysis.
