10422-1-AP

antibody from Proteintech Group

Targeting: SOX10 DOM, WS2E, WS4

Provider product page for 10422-1-AP

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [39]
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Product number: 10422-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#10422-1-AP, RRID:AB_2195371
Product name: SOX10 antibody
Antibody type: Polyclonal
Description: SOX10 antibody (Cat. #10422-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

SOX10 protein structure - 10422-1-AP shown in red.

Submitted references The SOX10-ACAT2-Cholesterol Synthesis Axis Is Required for Melanoma Proliferation.

Wang L, Dai C, Yang J, Ma Y, Ding X, Fan X
International journal of biological sciences 2026;22(4):1717-1732

Loss of SPECC1L in cranial neural crest cells results in increased hedgehog signaling and frontonasal dysplasia.

Tran AJ, Hufft-Martinez BM, Thalman DN, Maili L, McKinney SA, Goering JP, Trainor PA, Saadi I
Frontiers in physiology 2026;17:1751758

Decoding the Mechanisms of Pigment Reduction and Skin Rejuvenation Induced by Picosecond Laser: Insights From a Porcine Model.

Wang H, Li X, Xu Y, Tang H, Zeng W, Wen X
Lasers in surgery and medicine 2026 Feb;58(2):120-134

Wnt3a Inhibits Inflammatory Responses and Improves Survival in Immortalised Schwann Cells.

Zheng J, Zhang Y, Nan G
Journal of inflammation research 2025;18:17715-17730

Elevated ESM1 facilitates peripheral nerve regeneration via enhancing Schwann cell activity and developing a pro-regenerative microenvironment.

Ren Z, Miao Y, Zhang Y, Zhao L
Experimental neurology 2025 Sep 22;395:115476

Loss of SPECC1L in cranial neural crest cells results in increased hedgehog signaling and frontonasal dysplasia.

Tran AJ, Hufft-Martinez BM, Thalman DN, Maili L, McKinney S, Goering JP, Trainor PA, Saadi I
bioRxiv : the preprint server for biology 2025 Nov 23;

Flow Cytometric Analysis and Sorting of Murine Enteric Nervous System Cells: An Optimized Protocol.

Karkala F, de Bosscher I, Windster JD, Stroebel S, van Zanten L, Alves MM, Sacchetti A
International journal of molecular sciences 2025 May 18;26(10)

VGLL fusions define a new class of intraparenchymal central nervous system schwannoma.

Schmid S, Mirchia K, Tietze A, Liu I, Siewert C, Nückles J, Schittenhelm J, Behling F, Snuderl M, Hartmann C, Brandner S, Paine SML, Korshunov A, Hasselblatt M, Coras R, Epari S, Stadelmann C, Zechel S, Simon M, Wilson Y, Gianno F, Lucas CG Jr, Zherebitskiy V, Kaimaktchiev VB, Robinson L, Aldape K, Hoving EW, Tops BBJ, Perera AA, Göller P, Hernáiz Driever P, Wesseling P, Koch A, Perry A, Sahm F, Jones DTW, Capper D
Neuro-oncology 2025 May 15;27(4):1031-1045

H3K27 Trimethylation-Mediated Downregulation of miR-216a-3p in Sensory Neurons Regulates Neuropathic Pain Behaviors via Targeting STIM1.

Sun Y, Tao Y, Cao J, Zhang Y, Huang Z, Wang S, Lu W, Zhu Q, Shan L, Jiang D, Zhang Y, Tao J
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Jan 1;45(1)

Inhibition of the FEN1-PBX1 axis elicits cellular senescence in breast cancer via the increased intracellular reactive oxygen species levels.

Wu M, Wu B, Huang X, Wang Z, Zhu M, Zhu Y, Yu L, Liu J
Journal of translational medicine 2025 Feb 28;23(1):248

A Rapid Method to Immortalize Schwann Cells.

Zhang Y, Zheng J, Yao Y, He L, Liang S, Nan G
Pediatric discovery 2025 Dec;3(4):e70034

Transcript Imbalance from TENM4 Exon Skipping: Effects on Epilepsy and Genetic Pleiotropy.

Suzuki Y, Uehara DT, Enokido Y, Kawai T, Nomura N, Yamada K, Takanashi JI, Miyahara H, Inazawa J, Hayashi S
Molecular neurobiology 2025 Dec 26;63(1):324

Valproic acid boosts hair follicle stem cell resilience to oxygen-glucose deprivation through autophagy induction and AKT/mTOR suppression.

Keshavarzi F, Salehi MS, Pandamooz S, Dastghaib S, Siri M, Dianatpour M, Borhani-Haghighi A, Mostafavi-Pour Z, Mokarram P
Scientific reports 2025 Dec 10;16(1):2253

Valproic acid and/or rapamycin preconditioning protects hair follicle stem cells from oxygen glucose serum deprivation-induced oxidative injury via activating Nrf2 pathway.

Keshavarzi F, Salehi MS, Pandamooz S, Zare R, Zamani M, Mostafavi-Pour Z, Pooneh Mokarram P
Molecular biology research communications 2024;13(3):103-116

Directing Rat Hair Follicle Stem Cells Toward Neuronal Lineage With Enhanced Trophic Factor Expression.

Pandamooz S, Chavoshinezhad S, Mostaghel M, Rasekh A, Ghorbani N, Dara M, Pandamooz T, Tanideh N, Salehi MS
Advanced biomedical research 2024;13:84

Gut-induced alpha-Synuclein and Tau propagation initiate Parkinson's and Alzheimer's disease co-pathology and behavior impairments.

Xiang J, Tang J, Kang F, Ye J, Cui Y, Zhang Z, Wang J, Wu S, Ye K
Neuron 2024 Nov 6;112(21):3585-3601.e5

Mechanisms of PM(10) Disruption of the Nrf2 Pathway in Cornea.

Somayajulu M, Muhammed FS, Wright R, McClellan SA, Hazlett LD
International journal of molecular sciences 2024 Mar 28;25(7)

The role of serum/glucocorticoid-regulated kinase 1 in brain function following cerebral ischemia.

Wu CY, Zhang Y, Xu L, Huang Z, Zou P, Clemons GA, Li C, Citadin CT, Zhang Q, Lee RH
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Jul;44(7):1145-1162

Hypoxic Preconditioning Prevents Oxidative Stress-Induced Cell Death in Human Hair Follicle Stem Cells.

Salehi MS, Changiz Khani F, Ansari S, Mokhtari MJ, Dara M, Bayat M, Hooshmandi E, Ashjazadeh N, Borhani-Haghighi A, Ünal G, Pandamooz S
Iranian journal of biotechnology 2024 Jul;22(3):e3888

Identification of key regulatory genes involved in myelination after spinal cord injury by GSEA analysis.

Lv Y, Ji L, Dai H, Qiu S, Wang Y, Teng C, Yu B, Mi D, Yao C
Experimental neurology 2024 Dec;382:114966

Combination Therapy with Platelet-Rich Plasma and Epidermal Neural Crest Stem Cells Increases Treatment Efficacy in Vascular Dementia.

Akbari S, Haghani M, Ghobadi M, Hooshmandi E, Haghighi AB, Salehi MS, Pandamooz S, Azarpira N, Afshari A, Zabihi S, Nemati M, Bayat M
Stem cells international 2023;2023:3784843

A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia.

Laddach A, Chng SH, Lasrado R, Progatzky F, Shapiro M, Erickson A, Sampedro Castaneda M, Artemov AV, Bon-Frauches AC, Amaniti EM, Kleinjung J, Boeing S, Ultanir S, Adameyko I, Pachnis V
Nature communications 2023 Sep 22;14(1):5904

Oxytocin Receptor Expression in Hair Follicle Stem Cells: A Promising Model for Biological and Therapeutic Discovery in Neuropsychiatric Disorders.

Pandamooz S, Salehi MS, Jurek B, Meinung CP, Azarpira N, Dianatpour M, Neumann ID
Stem cell reviews and reports 2023 Oct;19(7):2510-2524

Combined use of hair follicle stem cells and CEPO (carbamylated erythropoietin)-Fc in a rat model of chronic cerebral hypoperfusion: A behavioral, electrophysiological, and molecular study.

Hooshmandi E, Akbari S, Pandamooz S, Ghobadi M, Ghasemi R, Maghsoudi N, Rai SN, Borhani-Haghighi A, Salehi MS, Azarpira N, YousefiNejad A, Haghani M, Bayat M
Behavioural brain research 2023 Oct 2;454:114655

Treatment with injectable platelet-rich fibrin in a rat model of melasma.

Liang ZX, Wang MR, Xiang XJ, Zhao Y
European journal of dermatology : EJD 2023 Oct 1;33(5):487-494

Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination.

Li L, Li D, Sun D, Zhang X, Lei W, Wu M, Huang Q, Nian X, Dai W, Lu X, Zhou Z, Zhu Y, Xiao Y, Zhang L, Mo W, Liu Z, Zhang L
Developmental cell 2023 Nov 6;58(21):2275-2291.e6

From Hair to the Brain: The Short-Term Therapeutic Potential of Human Hair Follicle-Derived Stem Cells and Their Conditioned Medium in a Rat Model of Stroke.

Karimi-Haghighi S, Pandamooz S, Jurek B, Fattahi S, Safari A, Azarpira N, Dianatpour M, Hooshmandi E, Bayat M, Owjfard M, Zafarmand SS, Mostaghel M, Mousavi SM, Jashire Nezhad N, Eraghi V, Fadakar N, Rahimi Jaberi A, Garcia-Esperon C, Spratt N, Levi C, Salehi MS, Borhani-Haghighi A
Molecular neurobiology 2023 May;60(5):2587-2601

The beneficial effects of chick embryo extract preconditioning on hair follicle stem cells: A promising strategy to generate Schwann cells.

Pandamooz S, Jurek B, Dianatpour M, Haerteis S, Limm K, Oefner PJ, Dargahi L, Borhani-Haghighi A, Miyan JA, Salehi MS
Cell proliferation 2023 Jul;56(7):e13397

Schwann cell-encapsulated chitosan-collagen hydrogel nerve conduit promotes peripheral nerve regeneration in rodent sciatic nerve defect models.

Takeya H, Itai S, Kimura H, Kurashina Y, Amemiya T, Nagoshi N, Iwamoto T, Sato K, Shibata S, Matsumoto M, Onoe H, Nakamura M
Scientific reports 2023 Jul 24;13(1):11932

Baicalein attenuates bleomycin-induced lung fibroblast senescence and lung fibrosis through restoration of Sirt3 expression.

Ji-Hong Y, Yu M, Ling-Hong Y, Jing-Jing G, Ling-Li X, Lv W, Yong-Mei J
Pharmaceutical biology 2023 Dec;61(1):288-297

miR-140 and miR-200 regulate the migratory heterogeneity of location-specific Schwann cell population.

Chen Q, Miao Y, Xu Z, Zhang R, Yi S
Journal of neurochemistry 2023 Aug;166(4):692-704

NeuroD4 converts glioblastoma cells into neuron-like cells through the SLC7A11-GSH-GPX4 antioxidant axis.

Wang H, Zhao P, Zhang Y, Chen Z, Bao H, Qian W, Wu J, Xing Z, Hu X, Jin K, Zhuge Q, Yang J
Cell death discovery 2023 Aug 15;9(1):297

Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes.

Redhead Y, Gibbins D, Lana-Elola E, Watson-Scales S, Dobson L, Krause M, Liu KJ, Fisher EMC, Green JBA, Tybulewicz VLJ
Development (Cambridge, England) 2023 Apr 15;150(8)

Machine learning-based identification of SOX10 as an immune regulator of macrophage in gliomas.

Xiao G, Wang K, Wang Z, Dai Z, Liang X, Ye W, Luo P, Zhang J, Liu Z, Cheng Q, Peng R
Frontiers in immunology 2022;13:1007461

Therapeutic potential of hair follicle-derived stem cell intranasal transplantation in a rat model of ischemic stroke.

Mousavi SM, Akbarpour B, Karimi-Haghighi S, Pandamooz S, Belém-Filho IJA, Masís-Calvo M, Salimi H, Lashanizadegan R, Pouramini A, Owjfard M, Hooshmandi E, Bayat M, Zafarmand SS, Dianatpour M, Salehi MS, Borhani-Haghighi A
BMC neuroscience 2022 Jul 25;23(1):47

TAZ inhibits acinar cell differentiation but promotes immature ductal cell proliferation in adult mouse salivary glands.

Miyachi Y, Nishio M, Otani J, Matsumoto S, Kikuchi A, Mak TW, Maehama T, Suzuki A
Genes to cells : devoted to molecular & cellular mechanisms 2021 Sep;26(9):714-726

Regulation of intestinal immunity and tissue repair by enteric glia.

Progatzky F, Shapiro M, Chng SH, Garcia-Cassani B, Classon CH, Sevgi S, Laddach A, Bon-Frauches AC, Lasrado R, Rahim M, Amaniti EM, Boeing S, Shah K, Entwistle LJ, Suárez-Bonnet A, Wilson MS, Stockinger B, Pachnis V
Nature 2021 Nov;599(7883):125-130

MicroRNA-22 contributes to dexamethasone-induced osteoblast differentiation inhibition and dysfunction through targeting caveolin-3 expression in osteoblastic cells.

Li P, Mao W, Zhang S, Zhang L, Chen Z, Lu Z
Experimental and therapeutic medicine 2021 Apr;21(4):336

MESP2 variants contribute to conotruncal heart defects by inhibiting cardiac neural crest cell proliferation.

Zhang E, Yang J, Liu Y, Hong N, Xie H, Fu Q, Li F, Chen S, Yu Y, Sun K
Journal of molecular medicine (Berlin, Germany) 2020 Jul;98(7):1035-1048

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