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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Chromatin Immunoprecipitation [1]
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Validation data
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- Product number
- HPA068898 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA068898, RRID:AB_2686054
- Product name
- Anti-SOX10
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SOX10, Gene description: SRY (sex determining region Y)-box 10, Alternative Gene Names: DOM, WS2E, WS4, Validated applications: IHC, ICC, ChIP, Uniprot ID: P56693, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Modeling primary microcephaly with human brain organoids reveals fundamental roles of CIT kinase activity
Schwann cell precursors represent a neural crest‐like state with biased multipotency
Pallavicini G, Moccia A, Iegiani G, Parolisi R, Peirent E, Berto G, Lorenzati M, Tshuva R, Ferraro A, Balzac F, Turco E, Salvi S, Myklebust H, Wang S, Eisenberg J, Chitale M, Girgla N, Boda E, Reiner O, Buffo A, Di Cunto F, Bielas S
Journal of Clinical Investigation 2024;134(21)
Journal of Clinical Investigation 2024;134(21)
Schwann cell precursors represent a neural crest‐like state with biased multipotency
Kastriti M, Faure L, Von Ahsen D, Bouderlique T, Boström J, Solovieva T, Jackson C, Bronner M, Meijer D, Hadjab S, Lallemend F, Erickson A, Kaucka M, Dyachuk V, Perlmann T, Lahti L, Krivanek J, Brunet J, Fried K, Adameyko I
The EMBO Journal 2022;41(17)
The EMBO Journal 2022;41(17)
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human cerebral cortex and liver tissues using HPA068898 antibody. Corresponding SOX10 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- ChIP-Exo-Seq composite graph for Anti-SOX10 (HPA068898, Lot 000049962) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.
