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- Antigen structure
- References [14]
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- Validations
- Immunohistochemistry [2]
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- Product number
- 17609-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17609-1-AP, RRID:AB_2305350
- Product name
- AKT2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AKT2 antibody (Cat. #17609-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Phosphorylated YBX2 is stabilized to promote glycolysis in brown adipocytes.
Simiao Wan and its ingredients alleviate type 2 diabetes mellitus via IRS1/AKT2/FOXO1/GLUT2 signaling.
miR-29b-3p Increases Radiosensitivity in Stemness Cancer Cells via Modulating Oncogenes Axis.
Akt3-mTOR regulates hippocampal neurogenesis in adult mouse.
Effects of CDKN2B-AS1 on cellular proliferation, invasion and AKT3 expression are attenuated by miR-424-5p in a model of ovarian endometriosis.
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues.
PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.
Regulation of MicroRNA-497-Targeting AKT2 Influences Tumor Growth and Chemoresistance to Cisplatin in Lung Cancer.
AKT2 drives cancer progression and is negatively modulated by miR-124 in human lung adenocarcinoma.
l-Theanine regulates glucose, lipid, and protein metabolism via insulin and AMP-activated protein kinase signaling pathways.
Hypoxia induces tumor cell growth and angiogenesis in non-small cell lung carcinoma via the Akt-PDK1-HIF1α-YKL-40 pathway.
Estrogen regulates miRNA expression: implication of estrogen receptor and miR-124/AKT2 in tumor growth and angiogenesis.
MicroRNA-137 Contributes to Dampened Tumorigenesis in Human Gastric Cancer by Targeting AKT2.
Zhao Q, Yu C, Xu X, Jin W, Zhang Z, Huang H, Gao Y, Pan D
iScience 2023 Oct 20;26(10):108091
iScience 2023 Oct 20;26(10):108091
Simiao Wan and its ingredients alleviate type 2 diabetes mellitus via IRS1/AKT2/FOXO1/GLUT2 signaling.
Xia T, Xu WJ, Hu YN, Luo ZY, He W, Liu CS, Tan XM
Frontiers in nutrition 2022;9:1012961
Frontiers in nutrition 2022;9:1012961
miR-29b-3p Increases Radiosensitivity in Stemness Cancer Cells via Modulating Oncogenes Axis.
Pan D, Du Y, Li R, Shen A, Liu X, Li C, Hu B
Frontiers in cell and developmental biology 2021;9:741074
Frontiers in cell and developmental biology 2021;9:741074
Akt3-mTOR regulates hippocampal neurogenesis in adult mouse.
Zhang T, Ding H, Wang Y, Yuan Z, Zhang Y, Chen G, Xu Y, Chen L
Journal of neurochemistry 2021 Nov;159(3):498-511
Journal of neurochemistry 2021 Nov;159(3):498-511
Effects of CDKN2B-AS1 on cellular proliferation, invasion and AKT3 expression are attenuated by miR-424-5p in a model of ovarian endometriosis.
Wang S, Yi M, Zhang X, Zhang T, Jiang L, Cao L, Zhou Y, Fang X
Reproductive biomedicine online 2021 Jun;42(6):1057-1066
Reproductive biomedicine online 2021 Jun;42(6):1057-1066
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Luo X, Cao M, Gao F, He X
Experimental hematology & oncology 2021 Jun 4;10(1):35
Experimental hematology & oncology 2021 Jun 4;10(1):35
Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues.
Xu Y, Shi T, Cui X, Yan L, Wang Q, Xu X, Zhao Q, Xu X, Tang QQ, Tang H, Pan D
The EMBO journal 2021 Dec 15;40(24):e108069
The EMBO journal 2021 Dec 15;40(24):e108069
PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.
Yan L, Jin W, Zhao Q, Cui X, Shi T, Xu Y, Li F, Jin W, Zhang Z, Zhang Z, Tang QQ, Pan D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Aug;8(16):e2102060
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Aug;8(16):e2102060
Regulation of MicroRNA-497-Targeting AKT2 Influences Tumor Growth and Chemoresistance to Cisplatin in Lung Cancer.
Wang L, Ji XB, Wang LH, Qiu JG, Zhou FM, Liu WJ, Wan DD, Lin MC, Liu LZ, Zhang JY, Jiang BH
Frontiers in cell and developmental biology 2020;8:840
Frontiers in cell and developmental biology 2020;8:840
AKT2 drives cancer progression and is negatively modulated by miR-124 in human lung adenocarcinoma.
Liu T, Zhu J, Du W, Ning W, Zhang Y, Zeng Y, Liu Z, Huang JA
Respiratory research 2020 Sep 1;21(1):227
Respiratory research 2020 Sep 1;21(1):227
l-Theanine regulates glucose, lipid, and protein metabolism via insulin and AMP-activated protein kinase signaling pathways.
Lin L, Zeng L, Liu A, Peng Y, Yuan D, Zhang S, Li Y, Chen J, Xiao W, Gong Z
Food & function 2020 Feb 26;11(2):1798-1809
Food & function 2020 Feb 26;11(2):1798-1809
Hypoxia induces tumor cell growth and angiogenesis in non-small cell lung carcinoma via the Akt-PDK1-HIF1α-YKL-40 pathway.
Miao Y, Wang W, Dong Y, Hu J, Wei K, Yang S, Lai X, Tang H
Translational cancer research 2020 Apr;9(4):2904-2918
Translational cancer research 2020 Apr;9(4):2904-2918
Estrogen regulates miRNA expression: implication of estrogen receptor and miR-124/AKT2 in tumor growth and angiogenesis.
Jiang CF, Li DM, Shi ZM, Wang L, Liu MM, Ge X, Liu X, Qian YC, Wen YY, Zhen LL, Lin J, Liu LZ, Jiang BH
Oncotarget 2016 Jun 14;7(24):36940-36955
Oncotarget 2016 Jun 14;7(24):36940-36955
MicroRNA-137 Contributes to Dampened Tumorigenesis in Human Gastric Cancer by Targeting AKT2.
Wu L, Chen J, Ding C, Wei S, Zhu Y, Yang W, Zhang X, Wei X, Han D
PloS one 2015;10(6):e0130124
PloS one 2015;10(6):e0130124
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 17609-1-AP(AKT2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AKT2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AKT2. This antibody recognizes human,mouse,rat antigen. The AKT2 antibody has been validated for the following applications: ELISA, IHC analysis.
