Antibody data
- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
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- Product number
- ABIN117900 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) antibody
- Antibody type
- Polyclonal
- Description
- Immunoaffinity purification.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antigen sequence
Synthetic peptide R-Y-D-S-L-G-L-L-E
-L-D-Q-R-T (correspond ing to aa 45
5-468 of 481)- Vial size
- 0.1 mg
- Storage
- Store undiluted at 2-8°C.
Submitted references Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta).
Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene.
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.
Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.
Peng XD, Xu PZ, Chen ML, Hahn-Windgassen A, Skeen J, Jacobs J, Sundararajan D, Chen WS, Crawford SE, Coleman KG, Hay N
Genes & development 2003 Jun 1;17(11):1352-65
Genes & development 2003 Jun 1;17(11):1352-65
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta).
Cho H, Mu J, Kim JK, Thorvaldsen JL, Chu Q, Crenshaw EB 3rd, Kaestner KH, Bartolomei MS, Shulman GI, Birnbaum MJ
Science (New York, N.Y.) 2001 Jun 1;292(5522):1728-31
Science (New York, N.Y.) 2001 Jun 1;292(5522):1728-31
Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene.
Altomare DA, Kozak CA, Sonoda G, Testa JR
Cytogenetics and cell genetics 1996;74(4):248-51
Cytogenetics and cell genetics 1996;74(4):248-51
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.
Cheng JQ, Ruggeri B, Klein WM, Sonoda G, Altomare DA, Watson DK, Testa JR
Proceedings of the National Academy of Sciences of the United States of America 1996 Apr 16;93(8):3636-41
Proceedings of the National Academy of Sciences of the United States of America 1996 Apr 16;93(8):3636-41
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.
Cheng JQ, Godwin AK, Bellacosa A, Taguchi T, Franke TF, Hamilton TC, Tsichlis PN, Testa JR
Proceedings of the National Academy of Sciences of the United States of America 1992 Oct 1;89(19):9267-71
Proceedings of the National Academy of Sciences of the United States of America 1992 Oct 1;89(19):9267-71
Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.
Staal SP
Proceedings of the National Academy of Sciences of the United States of America 1987 Jul;84(14):5034-7
Proceedings of the National Academy of Sciences of the United States of America 1987 Jul;84(14):5034-7
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