Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
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- Product number
- NBP2-47815-0.1mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Bax Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Bax Antibody (BAX/962) - Azide and BSA Free [NBP2-47815] - Human Melanoma stained with Bax Monoclonal Antibody (BAX/962).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Bax Antibody (BAX/962) - Azide and BSA Free [NBP2-47815] - Hodgkin's Lymphoma stained with Bax Monoclonal Antibody (BAX/962).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: Bax Antibody (BAX/962) - Azide and BSA Free [NBP2-47815] - Flow Cytometric Analysis of Jurkat cells using Bax Antibody (BAX/962) followed by Goat anti-mouse IgG-CF488 (Blue); Isotype Control (Red).