14-6997-81

antibody from Invitrogen Antibodies
Targeting: BAX BCL2L4
Provider product page for 14-6997-81
Western blot

Antibody data

Product number
14-6997-81 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-Bax Monoclonal Antibody (6A7), eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The 6A7 antibody reacts with mouse, rat, monkey and human Bax (20 kDa). The 6A7 antibody shows no cross-reaction with Bcl-2 or Bcl-xL proteins. Bcl-2, Bax, and Bcl-xL are members of a protein family that regulates apoptosis; while several family members including Bcl-2 and Bcl-xL inhibit apoptosis, overexpression of Bax promotes programmed cell death. A human Bax protein peptide sequence, aa 12-24, was used as immunogen. Applications Reported: The 6A7 antibody has been reported for use in immunoblotting (WB). Applications Tested: The 6A7 antibody has been tested by Western Blot and can be used at approximately 1 µg/mL. It is recommended that the reagent be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human, Mouse, Rat
Host
Mouse
Isotype
IgG
Antibody clone number
6A7
Vial size
50 µg
Concentration
0.5 mg/mL
Storage
4° C
BAX protein structure - 14-6997-81 shown in red.